Positive and Negative Interactions between Classical Antibacterial, Antibiotics, Antifungals and Natural Products

Dear Colleagues,

The increasing resistance of pathogenic bacteria and fungi to well-known antibiotics and synthetic chemotherapeutics is becoming a global healthcare concern. Therefore, there is a great need to develop strategies that are effective in the inhibition of the selection of resistant strains.

Many natural products and their constituents exhibit synergistic interactions with classical antimicrobial agents already approved for clinical use. Despite this, treating bacterial or fungal infections with a combination of classical antimicrobials and natural products is very uncommon. Still, investigations are required to confirm positive interactions between antimicrobials and compounds from natural products that are responsible for the enhanced antimicrobial effects. On the other hand, the possible negative influence of natural products on the activity of disinfectants, antibiotics, and synthetic antimicrobial chemotherapeutics must also be considered. Therefore, this Special Issue focuses on all aspects of the possible interactions (synergistic and antagonistic) between classical antimicrobials and natural products, their ingredients, and synthetic or semi-synthetic derivatives of these ingredients.

Dr. Piotr Szweda
Guest Editor

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• bacteria and fungi drug resistance
• natural products
• antibiotics
• synergism
• plant extracts
• essential oils
• bee products