Antimicrobial Perspective in Dentistry

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 2587

Special Issue Editor


E-Mail Website
Guest Editor
1. Private Practice, Messina, Italy
2. Department of Biomedicine and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, 40125 Bologna, Italy
Interests: dentistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The microorganic pattern of the oral cavity strictly depends on the interactions between the human body and the external environment, and its qualitative and quantitative alterations result in most dental and mouth diseases. The complexity and variability of the micro-community weaken the efficacy of chemical and physical antimicrobial agents, often limiting clinical approaches to surgical and structural corrections of impaired tissues. The oral hygiene recommendation contrasts with the ongoing irrational abuse of antibiotics prescriptions. Without a fundamental causal approach to an infectious problem, sometimes it is mandatory to interfere with medical treatments for systemic pathologies or renounce dental therapies so as not to compromise general health conditions.

Although challenging, the study of the antimicrobic approach will contribute to making dentistry a more and more scientific discipline.

The generical "antimicrobial" term defines the killing or replication-stopping effect that impacts all microorganisms, such as bacteria, viruses, and mitis, via different actions, such as antibiosis, antisepsis, and disinfection. Improving knowledge of oral microbiota would make it possible to find an adequate antimicrobial weapon for every situation, reducing antibiotic use to the correct indications.

Probiotics, photodynamic therapy, and antimicrobial peptides have been investigated to control oral infections. Nanoengineering strategies can help carry the antimicrobial agent to where its action is needed without damaging other areas.

We invite our colleagues to contribute to this Special Issue that involves, transversely, all the disciplines of oral and dental diseases, hoping to stimulate the relevant research and move towards new therapeutics prospectives.

Dr. Giuseppe Lizio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mouth diseases
  • oral microbial environment
  • antimicrobial approach

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

17 pages, 2819 KiB  
Systematic Review
Antibiotic Over-Prescription by Dentists in the Treatment of Apical Periodontitis: A Systematic Review and Meta-Analysis
by Juan A. Méndez-Millán, María León-López, Jenifer Martín-González, Juan J. Saúco-Márquez, Daniel Cabanillas-Balsera and Juan J. Segura-Egea
Antibiotics 2024, 13(4), 289; https://doi.org/10.3390/antibiotics13040289 - 22 Mar 2024
Cited by 2 | Viewed by 2221
Abstract
After pulp infection and necrosis, the passage of microbial antigens into the periapical space causes apical periodontitis (AP). Most of the clinical forms of AP can be managed without prescribing antibiotics, only with root canal treatment and abscess drainage or, where appropriate, tooth [...] Read more.
After pulp infection and necrosis, the passage of microbial antigens into the periapical space causes apical periodontitis (AP). Most of the clinical forms of AP can be managed without prescribing antibiotics, only with root canal treatment and abscess drainage or, where appropriate, tooth extraction. However, the scientific literature provides evidence of inappropriate antibiotic prescriptions by dentists in the management of apical disease. Objectives: The aim of this systematic review and meta-analysis was to analyze the global pattern of antibiotic prescription in the treatment of apical disease. Methods: PRISMA Guidelines were followed to carry out this systematic review. The research question was as follows: What is the pattern of antibiotic prescription by dentists in the treatment of the different clinical forms of apical periodontitis? A systematic search was conducted on MEDLINE/PubMed, Wiley Online Database, Web of Science and Scopus. All studies reporting data about the pattern of antibiotic prescription by dentists in the treatment of apical disease were included. The meta-analyses were calculated using the Open Meta Analyst version 10.10 software. Random-effects meta-analyses were performed. The risk of bias was assessed using the Newcastle–Ottawa Scale. The certainty of evidence was assessed using GRADE. Results: The search strategy identified 96 articles and thirty-nine cross-sectional studies fulfilled the inclusion criteria. The overall percentage of antibiotic prescriptions by dentists in cases of symptomatic AP was 25.8%, and 31.5% in cases of asymptomatic AP with sinus tract present. The percentage of dentists prescribing antibiotics in cases of acute apical abscess with no/mild symptoms was 47.7%, whereas, in cases of acute apical abscess with moderate/severe symptoms, 88.8% of dentists would prescribe antibiotics. Endodontists prescribe antibiotics at a lower rate than general practitioners. The total risk of bias was considered moderate, and the final rating for the certainty of the evidence was low. Conclusions: Dentists worldwide are over-prescribing antibiotics in the management of apical disease. It is necessary to improve antibiotic prescribing habits in the treatment of endodontic infections, as well as educational initiatives to encourage the rational and appropriate prescription of antibiotics in periapical diseases. Full article
(This article belongs to the Special Issue Antimicrobial Perspective in Dentistry)
Show Figures

Figure 1

Back to TopTop