Special Issue "Gastrointestinal Health of Dogs and Cats"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Companion Animals".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editor

Dr. Veronica Marchetti
E-Mail Website
Guest Editor
Veterinary Clinical Medicine Department, University of Pisa, 56126 Pisa, Italy
Interests: small animal gastroenterology; oncology; internal medicine; clinical pathology

Special Issue Information

Dear Colleagues,

I am excited to invite you to contribute to this Special Issue on animal gastroenterology that I have the honor of editing for Animals.

Gastroenterology in the daily lives of companion animals has become a dominant field with new approaches to the various gastroenterological diseases. The research on dysbiosis has allowed for a better understanding of its role in the pathophysiology of gastrointestinal inflammation, and in hepatic and pancreatic involvement.

This aspect has become very important in recent years and has made it necessary to review the therapeutic approaches. First of all, there are limitations regarding the use of antibiotics, respecting international guidelines for the control of antibiotic resistance. On the other hand, small animal gastroenterology, in line with human medicine, provides interesting research topics on the relationship between the digestive system and systems that may be directly or indirectly involved in the pathological process and in influencing the general prognosis and therapeutic approach.

This Special Issue of Animals aims to disseminate some of the most significant and recent research regarding gastroenterology in dogs and cats. Authors are invited to submit original research papers and review articles exploring hepatic, pancreatic and gastrointestinal diseases.

Dr. Veronica Marchetti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cats
  • dogs
  • intestinal disease
  • pancreatic disease
  • hepatic disease
  • dysbiosis
  • microbiota
  • systemic inflammatory response syndrome

Published Papers (1 paper)

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Research

Article
Evaluation of Prognostic Factors, including Duodenal P-Glycoprotein Expression, in Canine Chronic Enteropathy
Animals 2021, 11(8), 2315; https://doi.org/10.3390/ani11082315 - 05 Aug 2021
Viewed by 563
Abstract
The aim of this retrospective single-center study was to evaluate which factors, including expression of P-glycoprotein (P-gp), a membrane-bound protein involved in multiple drug resistance, could predict the response to treatment in canine immunosuppressant-responsive enteropathy (IRE). Dogs with IRE or non-responsive enteropathy (NRE) [...] Read more.
The aim of this retrospective single-center study was to evaluate which factors, including expression of P-glycoprotein (P-gp), a membrane-bound protein involved in multiple drug resistance, could predict the response to treatment in canine immunosuppressant-responsive enteropathy (IRE). Dogs with IRE or non-responsive enteropathy (NRE) that were examined from 2005 to 2014 were included and were divided into two groups (IRE vs. NRE). Signalment, history, and clinical and laboratory findings were collected. P-glycoprotein immunohistochemistry was carried out on duodenal biopsies of both groups stored in our biobank, and immunophenotyping and molecular clonality were performed on the NRE samples. Ninety-two dogs were enrolled, 73 IRE (79.3%) and 19 NRE (20.7%), with a prevalence of pure breed (78.3% vs. 21.7%) and male dogs (p < 0.001). Factors associated with a worse prognosis were previous treatment with steroids (p = 0.033) and lower serum total protein concentration (p = 0.005). Clonality testing on the NRE duodenal biopsies showed 5/16 clonal responses, assuming a latent undiagnosed lymphoma as a possible cause of the NRE. Full article
(This article belongs to the Special Issue Gastrointestinal Health of Dogs and Cats)
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