Mechanisms of Reproductive Dysfunction in Animals: From Cellular Insights to Environmental Insults
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Reproduction".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 23
Special Issue Editor
Interests: cytotoxicity; developmental toxicity; reproductive toxicity; acute toxicity; subchronic toxicity; chronic toxicity; toxic mechanism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Reproduction is fundamental in the survival of species, yet the tightly regulated systems that safeguard fertility remain highly fallible, as evidenced by the rising incidence of reproductive dysfunction. The regulation of reproductive function is inherently complex, operating across the cellular, endocrine, and environmental levels and beyond. This multiscale complexity prevents us from attaining a comprehensive understanding of how metabolic, hormonal, and environmental cues work together to ensure reproductive success, and it remains difficult to determine which regulatory tier exerts the most critical influence in maintaining fertility, particularly under stress, environmental insults, or pathological conditions. The increasing contamination of the environment due to toxic compounds is a major cause of reproductive defects. In order to devise effective therapeutic or preventive strategies that counteract the detrimental impacts of toxic compounds, it is essential that we systematically identify their molecular targets and delineate the pathways through which they impair reproductive function. Advancing our understanding of these processes requires an integrative research framework that spans the analytical spectrum, from in vitro molecular studies and toxicological assays to in vivo experiments and epidemiological investigations. This type of multidisciplinary approach is essential in developing a comprehensive understanding of reproductive toxicology, linking cellular and molecular insights to environmental insults, and informing strategies for fertility preservation and livestock management.
Dr. Fenglei Chen
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cytotoxicity
- developmental toxicity
- reproductive toxicity
- acute toxicity
- subchronic toxicity
- chronic toxicity
- toxic mechanism
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