Effects of Feed Additives on the Health and Performance of Monogastric Animals

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Nutrition".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 673

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Guest Editor
Department of Animal Science and Technology, National Taiwan University, Taipei 106, Taiwan
Interests: development of antibiotic alternatives in livestock production; ferroptosis: a mechanism shaping intestinal health; utilization of insect-based ingredients in livestock production
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Special Issue Information

Dear Colleagues,

The nutrition and health of monogastric animals—such as poultry, swine, and companion animals (dogs and cats)—are significantly influenced by dietary interventions. Among these, feed additives and functional ingredients have emerged as essential tools for enhancing growth performance, modulating gut microbiota, strengthening immune function, and improving nutrient utilization.

This Special Issue focuses on the latest research and developments related to feed additives and novel ingredients in monogastric animal nutrition. It welcomes studies on both traditional additives (e.g., probiotics, organic acids, enzymes) and emerging alternatives, such as insect-derived proteins, fermentation by-products, algae-based compounds, and postbiotic metabolites. Issues of ingredient safety, efficacy, regulatory compliance, and consumer acceptance are also of critical importance and within the scope of this Special Issue.

We encourage the submission of high-quality original research articles, review papers, short communications, and case studies that address, but are not limited to, the following topics:

  • Effects of feed additives on animal growth, feed efficiency, and productivity.
  • Gut health, intestinal morphology, and microbiota modulation.
  • Immune enhancement and disease resistance through dietary interventions.
  • Functional supplements and nutraceuticals in pet food.
  • Application and safety assessment of novel feed ingredients (e.g., insect protein, microalgae, mycoprotein).
  • Feed additive interactions and dose optimization.
  • Risk assessment and regulatory considerations of emerging feed materials.
  • Omics-based evaluations (e.g., metabolomics, transcriptomics) of additive impacts.
  • Sustainability, circular economy, and alternative protein sources in monogastric diets.

This Special Issue seeks to provide a platform for advancing interdisciplinary dialogue between animal scientists, nutritionists, veterinarians, food technologists, and industry professionals. Contributions that explore innovative, practical, and science-based approaches to improving monogastric animal health and production efficiency through dietary strategies are particularly welcome.

Dr. Yuan-Yu Lin
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • feed additives
  • monogastric animals
  • poultry
  • swine
  • dogs
  • cats
  • probiotics
  • phytogenics
  • functional pet food
  • gut health
  • insect protein
  • novel feed ingredients
  • immune modula-tion
  • safety assessment
  • performance enhancement
  • sustainable nutrition
  • antibiotic al-ternatives
  • metabolomics
  • pet food supplements

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Published Papers (1 paper)

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Research

18 pages, 2216 KB  
Article
Effects of Dietary Supplementation with Eucalyptus Essential Oil and Soy Isoflavones on the Growth Performance, Intestinal Health and Meat Quality of Weaned Meat Rabbits
by Chaowu Fu, Rao Li, Zhengpu Wei, Yurong Yang, Yan Zhang and Yibao Jiang
Animals 2025, 15(19), 2890; https://doi.org/10.3390/ani15192890 - 2 Oct 2025
Viewed by 440
Abstract
This study investigated the effects of individual and combined supplementation of eucalyptus essential oil (EEO) and soy isoflavones (SI) on the growth performance, intestinal health and meat quality of weaned meat rabbits. A total of 120 Ira female rabbits were stratified by body [...] Read more.
This study investigated the effects of individual and combined supplementation of eucalyptus essential oil (EEO) and soy isoflavones (SI) on the growth performance, intestinal health and meat quality of weaned meat rabbits. A total of 120 Ira female rabbits were stratified by body weight (BW) and randomly allocated into four treatment groups. The rabbits were fed for 35 days using (a) basal diet (Control), (b) basal diet + 150 mg/kg EEO, (c) basal diet + 25 mg/kg SI, or (d) basal diet + 150 mg/kg EEO + 25 mg/kg SI. The results showed that supplementing EEO and SI in the diet had a synergistic effect on production performance by increasing BW and average daily gain and reducing the feed intake/gain ratio. The EEO + SI group exhibited the most pronounced improvement in growth performance. Compared with the Control group, individual or combined supplementation significantly increased both semi-clean slaughter and total eviscerated slaughter rates, and showed a synergistic effect when supplemented together. The antioxidant capacity of the rabbits was enhanced, with the EEO + SI group showing the largest improvement. Serum biochemical analysis revealed that the combined treatment improved hepatic and cardiovascular functions. Additionally, we observed that the combined addition of EEO and SI has a synergistic effect on increasing the height of intestinal villi and the villus height/crypt depth ratio. Moreover, EEO and SI synergistically improved meat quality by elevating pH value, water-holding capacity, tenderness, and fat proportion. Notably, supplementation of EEO and SI in the diet regulated the composition of the intestinal microbiota, demonstrating increased relative abundance of beneficial Bacteroides and Lachnospiraceae_NK4A136_group. In conclusion, the combination of EEO and SI outperformed individual supplements in promoting growth and intestinal barrier function, potentially through enhancing antioxidant activity, attenuating oxidative stress, protecting the hepatic/cardiovascular systems, and improving intestinal morphology and microbial composition, thereby collectively enhancing growth performance, slaughter traits, and meat quality. Full article
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