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Animals
Special Issues
Microbiomics, Nutrigenomics and Molecular Biomarkers in Veterinary Clinical Research and...
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Microbiomics, Nutrigenomics and Molecular Biomarkers in Veterinary Clinical Research and Livestock Nutrition

A special issue of Animals (ISSN 2076-2615).

Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 3760

Special Issue Editors

Dr. Mohamed Zeineldin

E-Mail Website
Guest Editor
Integrated Food Animal Management Systems, Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
Interests: microbiome; bacterial genomics; antibiotic; antibiotic resistance
Special Issues, Collections and Topics in MDPI journals
Dr. Ahmed Elolimy

E-Mail Website
Guest Editor
1. Animal Production Department, National Research Centre, Dokki, 12622 Giza, Egypt
2. Department of Animal Sciences, University of Illinois at Urbana–Champaign, Urbana, IL, USA
Interests: diet; performance; maternal; efficiency; immunity; liver; gut; sequencing; bacteria; genes; metabolites; fermentation; neonates; cattle; calves; milk; EVs; HMOs; minerals; broiler; rabbits; goat; sheep; infants
Dr. Mohamed Abdelmegeid

E-Mail Website
Guest Editor
University of Veterinary Medicine Budapest, Department and Clinic for Production Animals, H-2225, Üllő – Dóra Major, Hungary
Interests: PCR; genetic engineering; gene expression; molecular biotechnology; gel electrophoresis; DNA; gene regulation; genomics; microbial molecular biology

Special Issue Information

Dear Colleagues,

Microbial cells—including bacteria, fungi, viruses, and archaea—are widely distributed among animals and have been found in different biogeographical locations, such as the gastrointestinal system, respiratory system, reproductive system, and skin. Collectively, these microbes and their genetic material are called the microbiome. The advancement of high-throughput technologies has propelled exponential increases in the understanding of the interaction between microbes and their host. Animal microbiome can be affected by various host and environmental factors, such as different management strategies, diet composition, physiological conditions, stress, and disease states. Therefore, it is of great importance to maintain the homeostasis of animal microbiome for proper health conditions and enhance animal efficiency. This research topic welcomes ongoing studies on molecular biomarkers and microbiome–diet–livestock interactions in health and disease status that may contribute towards enhancing animal health and profitability.

Dr. Mohamed Zeineldin
Dr. Ahmed Elolimy
Dr. Mohamed Abdelmegeid
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Microbiome
  • Nutrigenomics
  • Disease
  • Livestock
  • Biomarkers
  • Sequencing

Published Papers (1 paper)

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Research

18 pages, 3666 KiB  
Article
Insight View on the Role of in Ovo Feeding of Clenbuterol on Hatched Chicks: Hatchability, Growth Efficiency, Serum Metabolic Profile, Muscle, and Lipid-Related Markers
by Ahmed A. Saleh, Rashed A. Alhotan, Abdulrahman S. Alharthi, Eldsokey Nassef, Mohamed A. Kassab, Foad A. Farrag, Basma M. Hendam, Mohamed M. A. Abumnadour and Mustafa Shukry
Animals 2021, 11(8), 2429; https://doi.org/10.3390/ani11082429 - 18 Aug 2021
Cited by 5 | Viewed by 2849
Abstract
The present study aimed to assess the in ovo administration of clenbuterol on chick fertility, growth performance, muscle growth, myogenic gene expression, fatty acid, amino acid profile, intestinal morphology, and hepatic lipid-related gene expressions. In this study, 750 healthy fertile eggs from the [...] Read more.
The present study aimed to assess the in ovo administration of clenbuterol on chick fertility, growth performance, muscle growth, myogenic gene expression, fatty acid, amino acid profile, intestinal morphology, and hepatic lipid-related gene expressions. In this study, 750 healthy fertile eggs from the local chicken breed Dokki-4 strain were analyzed. Fertile eggs were randomly divided into five experimental groups (150 eggs/3 replicates for each group). On day 14 of incubation, in addition to the control group, four other groups were established where 0.5 mL of worm saline (30 °C) was injected into the second group of eggs. In the third, fourth, and fifth groups, 0.5 mL of worm saline (30 °C), 0.9% of NaCl, and 10, 15, and 20 ppm of clenbuterol were injected into the eggs. Results suggested that clenbuterol increased growth efficiency up to 12 weeks of age, especially at 15 ppm, followed by 10 ppm, decreased abdominal body fat mass, and improved hatchability (p < 0.01). Clenbuterol also modulated saturated fatty acid levels in the breast muscles and improved essential amino acids when administered at 10 and 15 ppm. Additionally, clenbuterol at 15 ppm significantly decreased myostatin gene expression (p < 0.01) and considerably increased IGF1r and IGF-binding protein (IGFBP) expression. Clenbuterol administration led to a significant upregulation of hepatic PPARα, growth hormone receptor, and Lipoprotein lipase (LPL) mRNA expression with a marked decrease in fatty acid synthase (FAS) and sterol regulatory element-binding protein 1 (SREBP-1c) expression. In conclusion, the current study revealed that in ovo injection of clenbuterol showed positive effects on the growth of hatched chicks through reduced abdominal fat deposition, improved intestinal morphology, and modulation of hepatic gene expressions in myogenesis, lipogenesis, and lipolysis. Full article
(This article belongs to the Special Issue Microbiomics, Nutrigenomics and Molecular Biomarkers in Veterinary Clinical Research and Livestock Nutrition)
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