Special Issue "Endocrine Disruptors Cause Metabolic and Reproductive Disorders: Effects on Laboratory, Cultured, and Wild Species"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Physiology".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editors

Dr. Francesca Maradonna
E-Mail Website
Guest Editor
Dipartimento Scienze della Vita e dell’Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy
Interests: fish reproduction; metabolic disorders; gametogenesis; epigenetic mechanisms
Dr. Giorgia Gioacchini
E-Mail Website
Guest Editor
Dipartimento Scienze della Vita e dell’Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, Ancona, Italy
Interests: fish reproduction; oogenesesis; spermatogenesis; aquaculture; fisheries; microplastic

Special Issue Information

Dear Colleagues,

The ability of some substances of anthropogenic origin to act as endocrine-disrupting chemicals (EDCs) by mimicking or blocking the activity of endogenous hormones represents a major threat to organism health. The consumption of contaminated food and water, and the inhalation of airborne pollutants, represent major sources of human and wildlife exposure to EDCs, significantly contributing to the onset of metabolic disorders by inappropriately perturbing lipid metabolism and energy balance. Most of these compounds can also interact with the hypothalamus–pituitary–gonadal axis, thus impairing reproductive processes. This large and multifaceted family includes plasticizers such as phthalates, bisphenols, alkylphenols, flame retardants, polycyclic aromatic hydrocarbons, pesticides, heavy metals, etc. So far, even though the biological effects of many of these compounds have been investigated, the chemical industry is constantly releasing new products in the environment, even before toxicity is tested, representing a concrete risk for organism health.

Taking the above into consideration, we would like to propose this Special Issue pointing out the need for further studies to increase knowledge regarding the toxicity of legacy EDCs, but also of less studied chemicals, in the light of increasing the awareness towards the use of safer alternatives.

In vitro and in vivo experimental studies, as well as review articles, are all welcome for consideration. Papers from different research areas of animal science, veterinary medicine, biology, biotechnology, and other related fields are invited to contribute to this Special Issue, which aims to cover all topics regarding the effects of endocrine disruptors on metabolism and reproduction in cultured and wild species, as well as in laboratory models.

Dr. Francesca Maradonna
Dr. Giorgia Gioacchini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • reproduction
  • metabolism
  • endocrine disruptors
  • gametogenesis
  • pollution

Published Papers

This special issue is now open for submission.
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