Recent Advances in CRISPR-Based Genome Editing in Crops

A special issue of Agriculture (ISSN 2077-0472). This special issue belongs to the section "Crop Genetics, Genomics and Breeding".

Deadline for manuscript submissions: 15 November 2025 | Viewed by 15

Special Issue Editors


E-Mail Website
Guest Editor
Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland, WA 99352, USA
Interests: synthetic biology; CRISPR; genome engineering; plant transformation; microbial strain engineering
Biology Department, University of Nebraska, Kearney, NE 68849-1130, USA
Interests: plant biotechnology; genetic engineering; genomics; CRISPR; forestry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

CRISPR-based genome editing has emerged as a transformative technology in plant biology, offering unprecedented precision, efficiency, and versatility in modifying crop genomes. Since its initial adaptation in plants, CRISPR has rapidly evolved from simple gene knockouts to sophisticated applications such as base editing, prime editing, gene regulation (CRISPRa/i), and epigenome modification. These innovations have opened new avenues for accelerating genetic improvement, enhancing stress tolerance, boosting yield and nutritional value in crop species, and thus addressing global agricultural challenges.

This Special Issue, titled "Recent Advances in CRISPR-Based Genome Editing in Crops", aims to showcase cutting-edge research and technological breakthroughs that shape the next generation of crop genetic engineering. We welcome original research articles, reviews, perspectives, and short communications that report novel CRISPR tools, delivery methods, multiplex genome editing, gene function studies, trait development, and regulatory or biosafety considerations. Submissions addressing CRISPR applications in both model and non-model crop species are encouraged.

By compiling the latest advancements and insights, this Special Issue seeks to provide a platform for researchers to share progress, challenges, and future directions in crop genome engineering. We particularly encourage interdisciplinary studies that integrate omics, synthetic biology, and systems biology approaches to unlock the full potential of CRISPR in agriculture.

Dr. Guoliang Yuan
Dr. Haiwei Lu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Agriculture is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • CRISPR
  • genome editing
  • crop improvement
  • base editing
  • prime editing
  • CRISPRa/i
  • plant biotechnology
  • trait development
  • multiplex editing
  • synthetic biology

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Published Papers

This special issue is now open for submission.
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