Mycotoxin Contamination in Farm Animals: Innovative Reduction Strategies

A special issue of Agriculture (ISSN 2077-0472). This special issue belongs to the section "Farm Animal Production".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1393

Special Issue Editors


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Guest Editor
Institute of Sciences of Food Production ISPA, Italian National Research Council, 70126 Bari, Italy
Interests: feed formulation; mycotoxin detoxifying agents; feed technology; food contaminants; mycotoxins chemistry; high-performance liquid chromatography; mass spectrometry; health risk
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E-Mail Website
Guest Editor
Institute of Sciences of Food Production ISPA, Italian National Research Council, 70126 Bari, Italy
Interests: feed formulation; mycotoxin detoxifying agents; feed technology; food contaminants; mycotoxins chemistry; high-performance liquid chromatography; mass spectrometry; health risk
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The contamination of food and animal feed by mycotoxins remains a significant agroeconomic challenge, leading to substantial economic losses. These losses stem from decreased growth performance and health disorders in farm animals, coupled with increased veterinary care costs. Mycotoxins, which are secondary metabolites produced by fungi, show toxic properties and are frequently found in cereal grains.

Due to the globalization of the feed ingredient trade and rapid climate changes, predicting the occurrence of mycotoxins has become increasingly challenging. In this scenario, the increase in mycotoxins co-occurrence is expected as well.

Mycotoxin contamination can occur at any stage of the feed supply chain, including crop cultivation, harvesting, storage, and the distribution of crops and compound feeds. To minimize mycotoxin contamination, preventative measures are essential.

Several approaches, including chemical and biological methods as well as the use of mycotoxin-detoxifying agents, are widely implemented to control mycotoxins in farm animals under field conditions. These latter agents can be categorized into bio-transforming and adsorbing agents based on their mode of action, according to a scientific report submitted to the European Food Safety Authority (EFSA). However, there remains a continuous need for the development of novel detection and decontamination strategies for effectively managing mycotoxin risks.

We invite you to contribute to this Special Issue by submitting original research, case studies, or review papers that provide insights into mycotoxicosis in farm animals and its implications for health disorders, as well as prevention strategies under field conditions. Your contributions will play a crucial role in advancing our understanding and management of mycotoxin risks.

We look forward to your submissions.

Dr. Vito D'Ascanio
Dr. Donato Greco
Guest Editors

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Keywords

  • mycotoxins
  • detoxifying agents
  • farm animals
  • biomarkers
  • prevention
  • climate change
  • mycotoxins occurrence

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Published Papers (1 paper)

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Research

10 pages, 1744 KiB  
Article
Effect of Dietary Supplementation of Mycotoxin Adsorbent on Laying Performance and Oviduct Health of Laying Hens in Aflatoxin B1 Exposed
by Yi Wei, Meng Sun, Jingjing Sun, Qiuyu Jiang and Bingkun Zhang
Agriculture 2024, 14(12), 2176; https://doi.org/10.3390/agriculture14122176 - 28 Nov 2024
Viewed by 932
Abstract
Aflatoxin contamination causes huge economic losses in animal husbandry by inhibiting growth and performance. The addition of mycotoxin binders to contaminate diets has been widely used for mycotoxin removal. Bentonite and yeast cell walls have received increasing attention as efficient and low-cost adsorbents. [...] Read more.
Aflatoxin contamination causes huge economic losses in animal husbandry by inhibiting growth and performance. The addition of mycotoxin binders to contaminate diets has been widely used for mycotoxin removal. Bentonite and yeast cell walls have received increasing attention as efficient and low-cost adsorbents. This study utilizes a mycotoxin adsorbent (MAB) to bind Aflatoxin B1 (AFB1) in feed. The trial was a randomized trial design, with 240 forty-three-week-old Hy-line Brown laying hens allocated to four groups, and with 80 birds in each group. The three diets used in the experiment were: (1) control diet; (2) control diet + 0.2 mg/kg AFB1; (3) control diet+ 0.2 mg/kg AFB1 + 2.0 g/kg MAB. All laying hens were fed a basal diet for one week. The feeding trial lasted for 12 weeks followed by a 1-week adaptation phase. The results show that laying hens fed the AFB1-contaminated diet had decreased performance and egg quality and reduced oviduct index and length. Blood biochemical parameters show that AFB1 leads to increased serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Compared to the control diet groups, exposure to the AFB1-contaminated diet resulted in liver and uterine tissue damage, mainly manifested by inflammatory infiltration. Compared with AFB1-contaminated diets, liver and uterine damage was alleviated with the AFB1 + MAB diet and partially restored to control levels. At the same time, we also observed that AFB1 treatment up-regulated the expression of Interferon-α (IFN-α), CASPASE-3, and CASPASE-8 in the uterus of laying hens, but this phenomenon was alleviated after adding the MAB. Therefore, under the experimental conditions, supplementation of MAB in AFB1-contaminated hen diets was an effective intervention to reduce aflatoxin toxicity. Full article
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