As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024 and 2025, which are listed below:

1. “Extracellular Matrix Components and Mechanosensing Pathways in Health and Disease”
by Aikaterini Berdiaki, Monica Neagu, Petros Tzanakakis, Ioanna Spyridaki, Serge Pérez and Dragana Nikitovic
Biomolecules 2024, 14(9), 1186; https://doi.org/10.3390/biom14091186
Full text available online: https://www.mdpi.com/2218-273X/14/9/1186

2. “How Do ROS Induce NETosis? Oxidative DNA Damage, DNA Repair, and Chromatin Decondensation”
by Dhia Azzouz and Nades Palaniyar
Biomolecules 2024, 14(10), 1307; https://doi.org/10.3390/biom14101307
Full text available online: https://www.mdpi.com/2218-273X/14/10/1307

3. “Astrocytes: The Stars in Neurodegeneration?”
by Katarina Stoklund Dittlau and Kristine Freude
Biomolecules 2024, 14(3), 289; https://doi.org/10.3390/biom14030289  
Full text available online: https://www.mdpi.com/2218-273X/14/3/289

4. “Factors and Mechanisms of Thyroid Hormone Activity in the Brain: Possible Role in Recovery and Protection”
by Laura Sabatino, Dominga Lapi and Cristina Del Seppia
Biomolecules 2024, 14(2), 198; https://doi.org/10.3390/biom14020198  
Full text available online: https://www.mdpi.com/2218-273X/14/2/198

5. “Mitochondrial Dysfunction as the Major Basis of Brain Aging”
by Stephen C. Bondy
Biomolecules 2024, 14(4), 402; https://doi.org/10.3390/biom14040402  
Full text available online: https://www.mdpi.com/2218-273X/14/4/402

6. “Space Flight Enhances Stress Pathways in Human Neural Stem Cells”
by Nicholas Carpo, Victoria Tran, Juan Carlos Biancotti, Carlos Cepeda and Araceli Espinosa-Jeffrey
Biomolecules 2024, 14(1), 65; https://doi.org/10.3390/biom14010065  
Full text available online: https://www.mdpi.com/2218-273X/14/1/65

7. “Comparison between the Regenerative and Therapeutic Impacts of Bone Marrow Mesenchymal Stem Cells and Adipose Mesenchymal Stem Cells Pre-Treated with Melatonin on Liver Fibrosis”
by Ahmed Elzainy, Abir El Sadik and Waleed Mohammad Altowayan
Biomolecules 2024, 14(3), 297; https://doi.org/10.3390/biom14030297  
Full text available online: https://www.mdpi.com/2218-273X/14/3/297

8. “Monogenic Disorders of ROS Production and the Primary Anti-Oxidative Defense”
by Nana-Maria Grüning and Markus Ralser
Biomolecules 2024, 14(2), 206; https://doi.org/10.3390/biom14020206  
Full text available online: https://www.mdpi.com/2218-273X/14/2/206

9. “Quercetin: Molecular Insights into Its Biological Roles”
by Hye Joon Boo, Danbi Yoon, Yujeong Choi, Younghyun Kim, Jeong Seok Cha and Jiho Yoo
Biomolecules 2025, 15(3), 313; https://doi.org/10.3390/biom15030313  
Full text available online: https://www.mdpi.com/2218-273X/15/3/313

10. “Autophagy and Cancer: Insights into Molecular Mechanisms and Therapeutic Approaches for Chronic Myeloid Leukemia”
by Mohd Adnan Kausar, Sadaf Anwar, Yusuf Saleem Khan, Ayman A. Saleh, Mai Ali Abdelfattah Ahmed, Simran Kaur, Naveed Iqbal, Waseem Ahmad Siddiqui and Mohammad Zeeshan Najm
Biomolecules 2025, 15(2), 215; https://doi.org/10.3390/biom15020215  
Full text available online: https://www.mdpi.com/2218-273X/15/2/215