2 July 2025
Biomedicines | Hot Papers in the “Cancer Biology and Oncology” Section

The “Cancer Biology and Oncology” Section publishes reviews and original peer-reviewed papers of a high scientific standard, covering all aspects of innovative cancer therapies. Papers aim to uncover novel therapeutic approaches toward overcoming conventional anticancer drug resistance and a better understanding of the interrelations between cancer and metabolism in addition to a better understanding of the tumor and its microenvironment, along with the discovery of novel diagnostic and prognostic makers. Topics include but are not limited to in vitro and in vivo cancer therapeutic responses, targeted therapies (including metabolism and immunotherapy, such as those involving CAR-T cells), identification of novel therapeutic targets, and evaluation of novel diagnosis and prognosis markers and the assessment of their impact on morphological, phenotypical, and molecular classifications.

1. “Dysbiosis Signature of Fecal Microbiota in Patients with Pancreatic Adenocarcinoma and Pancreatic Intraductal Papillary Mucinous Neoplasms”
by Theodoros Sidiropoulos, Nikolas Dovrolis, Hector Katifelis, Nikolaos V. Michalopoulos, Panagiotis Kokoropoulos, Nikolaos Arkadopoulos and Maria Gazouli
Biomedicines 2024, 12(5), 1040; https://doi.org/10.3390/biomedicines12051040
Available online: https://www.mdpi.com/2227-9059/12/5/1040

2. “IKZF1 Alterations and Therapeutic Targeting in B-Cell Acute Lymphoblastic Leukemia”
by Jonathan Paolino, Harrison K. Tsai, Marian H. Harris and Yana Pikman
Biomedicines 2024, 12(1), 89; https://doi.org/10.3390/biomedicines12010089
Available online: https://www.mdpi.com/2227-9059/12/1/89

3. “miR-331-5p Affects Motility of Thyroid Cancer Cell Lines and Regulates BID Expression”
by Francesca Maria Orlandella, Esther Imperlini, Katia Pane, Neila Luciano, Mariantonia Braile, Anna Elisa De Stefano, Paola Lucia Chiara Iervolino, Alessandro Ruocco, Stefania Orrù, Monica Franzese et al.
Biomedicines 2024, 12(3), 658. https://doi.org/10.3390/biomedicines12030658
Available online: https://www.mdpi.com/2227-9059/12/3/658

4. “Current and Emerging Diagnostic, Prognostic, and Predictive Biomarkers in Head and Neck Cancer”
by Hänel W. Eberly, Bao Y. Sciscent, F. Jeffrey Lorenz, Eleni M. Rettig and Neerav Goyal
Biomedicines 2024, 12(2), 415; https://doi.org/10.3390/biomedicines12020415
Available online: https://www.mdpi.com/2227-9059/12/2/415

5. “Tumor-Infiltrating Lymphocytes (TILs) in Breast Cancer: Prognostic and Predictive Significance across Molecular Subtypes”
by Aleksandra Ciarka, Michał Piątek, Rafał Pęksa, Michał Kunc and Elżbieta Senkus
Biomedicines 2024, 12(4), 763; https://doi.org/10.3390/biomedicines12040763
Available online: https://www.mdpi.com/2227-9059/12/4/763

6. “Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma or a Metaphor for Heterogeneity: From Single-Cell Analysis to Whole-Body Imaging”
by Rita Saúde-Conde, Ayça Arçay Öztürk, Kosta Stosic, Oier Azurmendi Senar, Julie Navez, Christelle Bouchart, Tatjana Arsenijevic, Patrick Flamen and Jean-Luc Van Laethem
Biomedicines 2024, 12(3), 591; https://doi.org/10.3390/biomedicines12030591
Available online: https://www.mdpi.com/2227-9059/12/3/591

7. “Molecular Pathology of Thyroid Tumors: Essential Points to Comprehend Regarding the Latest WHO Classification”
by Tomohiro Chiba
Biomedicines 2024, 12(4), 712; https://doi.org/10.3390/biomedicines12040712
Available online: https://www.mdpi.com/2227-9059/12/4/712

8. “Charting the Course in Sequencing Antibody-Drug Conjugates in Breast Cancer”
by Giuseppe Saltalamacchia, Rosalba Torrisi, Rita De Sanctis, Giovanna Masci, Chiara Miggiano, Mariangela Gaudio, Chiara Benvenuti, Flavia Jacobs, Riccardo Gerosa, Armando Santoro et al.
Biomedicines 2024, 12(3), 500; https://doi.org/10.3390/biomedicines12030500
Available online: https://www.mdpi.com/2227-9059/12/3/500

9. “Clinical Developments and Challenges in Treating FGFR2-Driven Gastric Cancer”
by David K. Lau, Jack P. Collin and John M. Mariadason
Biomedicines 2024, 12(5), 1117; https://doi.org/10.3390/biomedicines12051117
Available online: https://www.mdpi.com/2227-9059/12/5/1117

10. “Current Non-Metal Nanoparticle-Based Therapeutic Approaches for Glioblastoma Treatment”
by Agata M.Gawel, Anna Betkowska, Ewa Gajda, Marlena Godlewska and Damian Gawel
Biomedicines 2024, 12(8), 1822; https://doi.org/10.3390/biomedicines12081822
Available online: https://www.mdpi.com/2227-9059/12/8/1822

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN: 2227-9059). We would appreciate it if you would circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:

This Section is currently open for submissions. Papers may be submitted via the following link:

https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:

If you are an active researcher in the field of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

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