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Sclerosis, Volume 4, Issue 1

2026 March - 3 articles

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Articles (3)

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Communication

221 Views

7 Pages

Short Report: Treadmill Walking Differs from Overground Walking in Multiple Sclerosis

Herbert Karpatkin,
Jaya Rachwani,
Evan T. Cohen,
Anna Rubeo,
Gene Hetz,
Rosangelis Rodriguez and
Lourdes Rodriguez

Sclerosis2026, 4(1), 3;https://doi.org/10.3390/sclerosis4010003

16 January 2026

Background/Objectives: Gait impairment is a common finding in multiple sclerosis (MS). Clinicians have used both treadmill and overground walking for its evaluation and treatment. However, there is little evidence that these two types of walking are...

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Review

461 Views

18 Pages

Bridging Silence: A Scoping Review of Technological Advancements in Augmentative and Alternative Communication for Amyotrophic Lateral Sclerosis

Filipe Gonçalves,
Carla S. Fernandes,
Margarida I. Teixeira,
Cláudia Melo and
Cátia Dias

Sclerosis2026, 4(1), 2;https://doi.org/10.3390/sclerosis4010002

13 January 2026

Background: Amyotrophic lateral sclerosis (ALS) progressively impairs motor function, compromising speech and limiting communication. Augmentative and alternative communication (AAC) is essential to maintain autonomy, social participation, and qualit...

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Review

505 Views

17 Pages

Bruton’s Tyrosine Kinase Inhibitors and Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis: A Review of Complementary Paradigms for a Divergent Disease

Wilhelmina Hauwanga,
Mariyam Fathima Salim,
Maha Awan,
Lynda Amaka Ezike,
Ida Ann Veronica Fredrick Luther,
Mustafa Suliman,
Jeshua Nathaniel Devan and
Billy McBenedict

Sclerosis2026, 4(1), 1;https://doi.org/10.3390/sclerosis4010001

4 January 2026

Multiple sclerosis (MS) is a heterogeneous autoimmune disease driven by peripheral immune dysregulation and compartmentalized central nervous system (CNS) inflammation. Despite more than 20 approved disease-modifying therapies, disability accrual rem...

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