- Review
Role of Oxygen Radicals in Alzheimer’s Disease: Focus on Tau Protein
- Anna Atlante,
- Daniela Valenti,
- Valentina Latina and
- Giuseppina Amadoro
Oxygen free radical burst is a prominent early event in the pathogenesis of Alzheimer’s disease (AD). Posttranslational modifications of Tau protein, primarily hyper-phosphorylation and truncation, are indicated as critical mediators of AD path...