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International Journal of Translational Medicine, Volume 2, Issue 1

March 2022 - 10 articles

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Articles (10)

  • Review
  • Open Access
6 Citations
7,034 Views
21 Pages

Thinking Outside the Box: Utilizing Nontraditional Animal Models for COVID-19 Research

  • Sachithra Gunasekara,
  • Miruthula Tamil Selvan,
  • Craig A. Miller and
  • Jennifer M. Rudd

The ongoing COVID-19 pandemic continues to affect the lives, wellbeing, and stability of communities worldwide. The race to save human lives is critical, and the development of useful translational animal models to elucidate disease pathogenesis and...

  • Article
  • Open Access
3 Citations
4,237 Views
16 Pages

A Multimodal Omics Exploration of the Motor and Non-Motor Symptoms of Parkinson’s Disease

  • François-Xavier Lejeune,
  • Farid Ichou,
  • Etienne Camenen,
  • Benoit Colsch,
  • Florence Mauger,
  • Caroline Peltier,
  • Ivan Moszer,
  • Emmanuel Gilson,
  • Morgane Pierre-Jean and
  • Edith Le Floch
  • + 6 authors

Parkinson’s disease (PD) is the second most common neurodegenerative disease clinically characterized by classical motor symptoms and a range of associated non-motor symptoms. Due to the heterogeneity of symptoms and variability in patient prog...

  • Article
  • Open Access
3 Citations
3,887 Views
19 Pages

Serum Metabolic Profiling Identifies Key Differences between Patients with Single-Ventricle Heart Disease and Healthy Controls

  • Julie Pires da Silva,
  • Ashley E. Pietra,
  • Angela N. Baybayon-Grandgeorge and
  • Anastacia M. Garcia

23 February 2022

There are growing numbers of infants and children living with single-ventricle congenital heart disease (SV). However, cardiac dysfunction and, ultimately, heart failure (HF) are common in the SV population and the ability to predict the progression...

  • Article
  • Open Access
3 Citations
3,064 Views
12 Pages

Brixia Score in Outcomes of Alpha versus Delta Variant of Infection in Pregnant Critical COVID-19 Patients

  • Roxana Covali,
  • Demetra Socolov,
  • Ioana Pavaleanu,
  • Mona Akad,
  • Lucian Vasile Boiculese and
  • Razvan Socolov

17 February 2022

Background: Critical COVID-19 patients account for 1.7 to 13% of all pregnant COVID-19 patients. Methods: Patients admitted to the COVID-19 intensive care unit of Elena Doamna Obstetrics and Gynecology University Hospital in Iasi between 1 January an...

  • Review
  • Open Access
9 Citations
6,318 Views
14 Pages

Urinary tract infections (UTIs) are among the most common infective disease in the adult population. UTI diagnosis is based essentially on the presence of lower urinary tract symptoms (e.g., dysuria, urgency, and frequency) and the evidence of bacter...

  • Article
  • Open Access
8 Citations
3,789 Views
10 Pages

Diabetic retinopathy (DR) remains a prevalent complication of diabetes and a major cause of vision loss among the working population. Selective loss of pericytes and vascular smooth muscle cells (SMCs), the mural cells of the retinal blood vessels, i...

  • Article
  • Open Access
12 Citations
6,175 Views
15 Pages

Diabetic retinopathy (DR) is the most common complication of diabetes and a major cause of vision loss worldwide. The premature death of the microvascular mural cells represents both a pathological hallmark of vasodegeneration in DR and a basis for t...

  • Article
  • Open Access
17 Citations
4,916 Views
9 Pages

Artificial Intelligence and Democratization of the Use of Lung Ultrasound in COVID-19: On the Feasibility of Automatic Calculation of Lung Ultrasound Score

  • Jorge Camacho,
  • Mario Muñoz,
  • Vicente Genovés,
  • Joaquín L. Herraiz,
  • Ignacio Ortega,
  • Adrián Belarra,
  • Ricardo González,
  • David Sánchez,
  • Roberto Carlos Giacchetta and
  • Ángela Trueba-Vicente
  • + 1 author

During the COVID-19 pandemic, lung ultrasound has been revealed as a powerful technique for diagnosis and follow-up of pneumonia, the principal complication of SARS-CoV-2 infection. Nevertheless, being a relatively new and unknown technique, the lack...

  • Review
  • Open Access
4 Citations
4,530 Views
16 Pages

Early Neural Changes as Underlying Pathophysiological Mechanism in Diabetic Retinopathy

  • Antolín Cantó,
  • Javier Martínez,
  • Giuliana Perini-Villanueva,
  • María Miranda and
  • Eloy Bejarano

Diabetes mellitus is a chronic disease often accompanied by diabetic retinopathy (DR), one of the most common diabetic complications. DR is an eye condition that causes vision deficiency and often leads to blindness. DR develops when blood vessels da...

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Int. J. Transl. Med. - ISSN 2673-8937