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Nanomanufacturing, Volume 5, Issue 2 (June 2025) – 2 articles

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12 pages, 3972 KiB  
Article
Anticancer Activity of Cerium Oxide Nanoparticles Towards Human Lung Cancer Cells
by Nithin Krisshna Gunasekaran, Nicole Nazario Bayon, Prathima Prabhu Tumkur, Krishnan Prabhakaran, Joseph C. Hall and Govindarajan T. Ramesh
Nanomanufacturing 2025, 5(2), 6; https://doi.org/10.3390/nanomanufacturing5020006 - 3 Apr 2025
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Abstract
Cerium oxide nanoparticles (CeO2 NPs) have gained significant attention in various fields, including biomedicine, semiconductors, cosmetics, and fuel cells, due to their unique physico-chemical properties. Notably, green-synthesized CeO2 NPs have demonstrated enhanced potential as drug carriers, particularly in biomedical applications such [...] Read more.
Cerium oxide nanoparticles (CeO2 NPs) have gained significant attention in various fields, including biomedicine, semiconductors, cosmetics, and fuel cells, due to their unique physico-chemical properties. Notably, green-synthesized CeO2 NPs have demonstrated enhanced potential as drug carriers, particularly in biomedical applications such as anti-inflammatory, anticancer, antimicrobial, and anti-oxidant therapies. This study aimed to investigate the anticancer effects of cerium oxide nanoparticles synthesized using turmeric rhizomes on human lung cancer cells. The cytotoxicity and proliferation inhibition of these nanoparticles were assessed using MTT and Live/Dead assays, revealing a dose-dependent reduction in cell viability. Additionally, reactive oxygen species (ROS) generation was quantified through ROS assays, confirming oxidative stress induction as a key mechanism of cytotoxicity. Cell proliferation analysis further demonstrated that increasing concentrations of CeO2 NPs significantly reduced the multiplication of healthy lung cancer cells. These findings highlight the potential of turmeric-derived CeO2 NPs as a promising therapeutic agent for lung cancer treatment, warranting further exploration of their mechanism of action and in vivo efficacy. Full article
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17 pages, 4841 KiB  
Article
Fabricating Silver Nanowire–IZO Composite Transparent Conducting Electrodes at Roll-to-Roll Speed for Perovskite Solar Cells
by Justin C. Bonner, Bishal Bhandari, Garrett J. Vander Stouw, Geethanjali Bingi, Kurt A. Schroder, Julia E. Huddy, William J. Scheideler and Julia W. P. Hsu
Nanomanufacturing 2025, 5(2), 5; https://doi.org/10.3390/nanomanufacturing5020005 - 29 Mar 2025
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Abstract
This study addresses the challenges of efficient, large-scale production of flexible transparent conducting electrodes (TCEs). We fabricate TCEs on polyethylene terephthalate (PET) substrates using a high-speed roll-to-roll (R2R) compatible method that combines gravure printing and photonic curing. The hybrid TCEs consist of Ag [...] Read more.
This study addresses the challenges of efficient, large-scale production of flexible transparent conducting electrodes (TCEs). We fabricate TCEs on polyethylene terephthalate (PET) substrates using a high-speed roll-to-roll (R2R) compatible method that combines gravure printing and photonic curing. The hybrid TCEs consist of Ag metal bus lines (Ag MBLs) coated with silver nanowires (AgNWs) and indium zinc oxide (IZO) layers. All materials are solutions deposited at speeds exceeding 10 m/min using gravure printing. We conduct a systematic study to optimize coating parameters and tune solvent composition to achieve a uniform AgNW network. The entire stack undergoes photonic curing, a low-energy annealing method that can be completed at high speeds and will not damage the plastic substrates. The resulting hybrid TCEs exhibit a transmittance of 92% averaged from 400 nm to 1100 nm and a sheet resistance of 11 Ω/sq. Mechanical durability is tested by bending the hybrid TCEs to a strain of 1% for 2000 cycles. The results show a minimal increase (<5%) in resistance. The high-throughput potential is established by showing that each hybrid TCE fabrication step can be completed at 30 m/min. We further fabricate methylammonium lead iodide solar cells to demonstrate the practical use of these TCEs, achieving an average power conversion efficiency (PCE) of 13%. The high-performance hybrid TCEs produced using R2R-compatible processes show potential as a viable choice for replacing vacuum-deposited indium tin oxide films on PET. Full article
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