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Transplantology, Volume 2, Issue 4

December 2021 - 11 articles

Cover Story: Animal models link in vitro research and first-in-man application during clinical trials. They provide substantial information in preclinical studies to assess new therapeutic interventions. Transplantation research is a discipline that largely benefits from the use of animal models, with mouse and pig models being the most frequently used models in organ transplantation research. A suitable animal model should best reflect the situation in humans, and the researcher should be aware of the similarities and limitations of the selected model. Therefore, it is crucial to select the most appropriate animal model from which extrapolations and valid conclusions can be obtained and translated into the human situation. This review provides an overview of the models frequently used in organ transplantation research. View this paper.

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Article

2 Citations

4,043 Views

8 Pages

Usefulness of T-Tube in Liver Transplantation: Still Effective or Outmoded Strategy?

Niccolò Incarbone,
Riccardo De Carlis,
Leonardo Centonze,
Livia Palmieri,
Giuseppe Cordaro,
Alberto Ficarelli,
Ivan Vella,
Vincenzo Buscemi,
Andrea Lauterio and
Luciano De Carlis

Transplantology2021, 2(4), 379-386;https://doi.org/10.3390/transplantology2040036

24 September 2021

Introduction: T-tube placement during liver transplantation (LT) is still debated. We performed a retrospective study to evaluate the usefulness of T-tube after LT in two cohorts differing in post-transplant risk. Methods: A total of 327 LTs performe...

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Transplantology - ISSN 2673-3943

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