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Proceedings, Volume 100, Issue 1

2024 IECC 2024 - 25 articles

The 4th International Electronic Conference on Cancers

Online | 6–8 March 2024

Volume Editors:
Angeliki Magklara, University of Ioannina/Foundation of Research and Technology-Hellas, Greece
Shinji Kawabata, Osaka Medical and Pharmaceutical University, Japan
Alfredo Conti, IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy
Vasso Apostolopoulos, Victoria University, Melbourne, Australia

Cover Story: The 4th International Electronic Conference on Cancers (IECC 2024), organized by the MDPI journal Cancers, was an online event held on 6–8 March 2024. This conference aspires to bring together clinicians and scientists with diverse expertise and perspectives in cancer research to interact, exchange ideas, and form new collaborations that may lead to new advancements in scientific understanding and ultimately impact patient outcomes. IECC 2024 was dedicated to the following topics: Brain Metastases, Cancer Biomarkers, Cancer Immunology and Immunotherapy, Tumor Microenvironment, Molecular Cancer Biology, Cancer Epidemiology and Prevention, Cancer Therapy, and Cancer Pathophysiology.
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Articles (25)

  • Editorial
  • Open Access
1,608 Views
4 Pages

The 4th International Electronic Conference on Cancers (IECC 2024), organized by the MDPI journal Cancers, was an online event held on 6–8 March 2024 [...]

  • Abstract
  • Open Access
798 Views
2 Pages

Glioblastoma multiforme (GBM) is the most common aggressive malignant primary brain tumor, afflicting approximately 3 in every 100,000 persons in the United States, with an incidence rate that is 1 [...]

  • Abstract
  • Open Access
1 Citations
3,082 Views
2 Pages

Lung cancer remains a formidable global health challenge, necessitating the exploration of innovative diagnostic approaches for early detection. This review paper delves into the burgeoning field of exhaled breath analysis using electronic nose (e-no...

  • Abstract
  • Open Access
1,249 Views
2 Pages

Metabolic Strategies of Treg Cells in the Tumor Microenvironment: Implications for Immune Metabolism-Based Precision Medicine

  • Devendra Kumar Mishra,
  • Sandeep Yadav,
  • Sumit Chaudhari,
  • Ila Dixit,
  • Lavkush Tiwari,
  • Khalid Abdul Waheed,
  • Shubham Shukla and
  • Savita Upadhyay

In recent years, the complex relationship between immune cells and the area around the tumour has become an important factor in how cancer grows and how well treatment works [...]

  • Abstract
  • Open Access
1 Citations
1,016 Views
2 Pages

Cancer Stem Cells as Potential Targets of Phytotoxic Alkaloids: Drug-Likeness Prediction and Molecular Docking Studies

  • Charles Okeke Nnadi,
  • Simnom Hope Banda,
  • Michael Uchechukwu Uzonwanne and
  • Obinna Kenneth Didigwu

Targeting cancer stem cells (CSCs) in anticancer discovery is very difficult due to the resistance of CSCs to conventional drugs, their low proliferation rate, improved DNA damage repair, and the overexpression of anti-apoptotic proteins and multidru...

  • Abstract
  • Open Access
2 Citations
1,121 Views
2 Pages

Exposure to Mycovirus-Containing Aspergillus flavus Alters Transcription Factors in Normal and Leukemia Cell Lines

  • Cameron K. Tebbi,
  • Eva Sahakian,
  • Jiyu Yan,
  • Saumil Patel and
  • Melanie Mediavilla-Varela

Transcription factors bind specific DNA motifs to regulate the expression of target genes in order to maintain normal hematopoiesis [...]

  • Abstract
  • Open Access
2 Citations
875 Views
2 Pages

Therapeutic peptides have emerged as a promising frontier in the development of anti-cancer agents, classified into three main groups: antimicrobial/pore-forming peptides, cell-permeable peptides, and tumor-targeting peptides [...]

  • Abstract
  • Open Access
908 Views
2 Pages

Noncoding Regulatory Mutations as a Driving Event for the Oncogenic Core Regulatory Circuitries of Neuroblastoma

  • Vincenzo Aievola,
  • Vito Alessandro Lasorsa,
  • Annalaura Montella,
  • Ferdinando Bonfiglio,
  • Marianna Avitabile,
  • Teresa Maiorino,
  • Matilde Tirelli,
  • Giuseppe D’Alterio,
  • Matthias Fischer and
  • Mario Capasso
  • + 2 authors

Neuroblastoma (NB) is a pediatric tumor composed of adrenergic (ADRN) and mesenchymal-like (MES) cells which derive from the dysregulation of normal cell differentiation imposed by NB Core Regulatory Circuitries (CRCs) [...]

  • Abstract
  • Open Access
1,010 Views
2 Pages

Post-GWAS Functional Analysis of the 11p11.2 Risk Locus Identifies HSD17B12 as a Neuroblastoma Susceptibility Gene Involved in Lipid Metabolism

  • Teresa Maiorino,
  • Marianna Avitabile,
  • Vito Alessandro Lasorsa,
  • Annalaura Montella,
  • Sueva Cantalupo,
  • Matilde Tirelli,
  • Martina Morini,
  • Alessandra Eva,
  • Marianna Caterino and
  • Mario Capasso
  • + 4 authors

Genome-wide association studies (GWASs) have contributed to the study of neuroblastoma (NB) genetics by identifying common risk variants that activate cancer-related processes associated with NB susceptibility [...]

  • Abstract
  • Open Access
934 Views
2 Pages

Evaluation of the Safety of Folate Receptor-Targeted Boron Carrier in Boron Neutron Capture Therapy (BNCT) for Malignant Gliomas Using CED Administration

  • Kohei Tsujino,
  • Hideki Kashiwagi,
  • Ryo Kayama,
  • Yoshiki Fujikawa,
  • Yusuke Fukuo,
  • Ryo Hiramatsu,
  • Naosuke Nonoguchi,
  • Takushi Takata,
  • Hiroki Tanaka and
  • Shinji Kawabata
  • + 6 authors

Knowing how to accumulate boron into the tumor cells is a crucial aspect of boron neutron capture therapy (BNCT), which can be targeted at the cellular level, and the development of novel boron agents other than BPA, which is used in clinical practic...

  • Abstract
  • Open Access
1 Citations
1,140 Views
2 Pages

Chordoma Treatment with Boron Neutron Capture Therapy (BNCT): Experimental Insights

  • Yoshiki Fujikawa,
  • Shinji Kawabata,
  • Kohei Tsujino,
  • Hideki Kashiwagi,
  • Yusuke Fukuo,
  • Ryo Hiramatsu,
  • Hiroki Tanaka,
  • Naonori Hu,
  • Toshihiro Takami and
  • Masahiko Wanibuchi

Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]

  • Abstract
  • Open Access
1,132 Views
2 Pages

The most common forms of primary brain tumors are low-grade astrocytoma (ACT) tumors and their progression to the glioblastoma multiforme (GBM), in a high-aggressiveness form. Understanding mechanisms of progression is necessary, and mitochondrial me...

  • Abstract
  • Open Access
953 Views
2 Pages

Aberrantly Expressed Long Non-Coding RNAS and mRNAS in Breast Cancer and Their Interaction

  • Elena Filippova,
  • Svetlana Lukina,
  • Irina Pronina,
  • Alexey Burdenny,
  • Tatiana Kazubskaya,
  • Vitaly Loginov and
  • Eleonora Braga

According to the latest global statistics for 2020, breast cancer (BC) has taken first place in the incidence of epithelial tumors, ahead of lung cancer, and is the main cause of mortality from cancer pathology among women around the world [...]

  • Abstract
  • Open Access
743 Views
1 Page

Aims: Medulloblastoma (MBs), the most prevalent malignant paediatric brain tumour, exhibits distinct subgroups—Wingless (WNT), Sonic Hedgehog (SHH), Group 3 (G3), and Group 4 (G4)—and each is characterized by unique molecular signatures a...

  • Abstract
  • Open Access
1,511 Views
3 Pages

Lung cancer is the third most common cancer in women and the most common cancer in males. Chemotherapy, allopathy, hormone therapy, radiation therapy, surgery, immune system, and targeted therapies are frequently used to treat lung cancer. These medi...

  • Abstract
  • Open Access
1,157 Views
2 Pages

Pharmacological Network Study on the Effect of Quercetin on Gastric Cancer Using Computerized Databases

  • Sergio Raúl Zúñiga-Hernández,
  • Trinidad García-Iglesias,
  • Monserrat Macías-Carballo,
  • Juan Manuel Guzmán-Flores and
  • Christian Martin Rodríguez-Razón

Gastric cancer (GC) is the second most common cause of death of any cancer-related cases in the world, and is also in the top 5 most common malignancy cancers in general. There are plenty of well-distributed treatments, offering better hygiene, more...

  • Abstract
  • Open Access
990 Views
2 Pages

Exploring BNCT as a Novel Approach for Metastatic Spinal Tumor Management

  • Yoshiki Fujikawa,
  • Shinji Kawabata,
  • Kohei Tsujino,
  • Ryo Kayama,
  • Hideki Kashiwagi,
  • Yusuke Fukuo,
  • Ryo Hiramatsu,
  • Takushi Takata,
  • Hiroki Tanaka and
  • Masahiko Wanibuchi
  • + 4 authors

[Background] Boron neutron capture therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]

  • Abstract
  • Open Access
1,070 Views
2 Pages

Development of Synergetic Combinations of a Novel Apoptosis Inducer with AKT and Hsp90 Selective Inhibitors Targeting Hormone-Sensitive and Hormone-Resistant Breast Cancer Cells

  • Diana I. Salnikova,
  • Stepan K. Krymov,
  • Danila V. Sorokin,
  • Fedor B. Bogdanov,
  • Olga E. Andreeva,
  • Alvina I. Khamidullina,
  • Andrey E. Shchekotikhin and
  • Alexander M. Scherbakov

Introduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]

  • Abstract
  • Open Access
1,108 Views
1 Page

Hepatocellular Carcinoma (HCC), a formidable global health challenge, continues to claim numerous lives due to its asymptomatic nature in the early stages and limited treatment options. In this ever-evolving landscape of cancer research, pseudogenes,...

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Proceedings - ISSN 2504-3900