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Abstract

Unveiling the Smell of Health: E-Nose-Based Volatile Organic Compound Analysis of Exhaled Breath in Early Lung Cancer Detection †

1
Department of Electronics Engineering, Saintgits College of Engineering, Kottayam 686532, India
2
Department of Computer Science and Engineering, Saintgits College of Engineering, Kottayam 686532, India
*
Author to whom correspondence should be addressed.
Presented at the 4th International Electronic Conference on Cancers, 6–8 March 2024; Available online: https://sciforum.net/event/IECC2024.
Proceedings 2024, 100(1), 23; https://doi.org/10.3390/proceedings2024100023
Published: 29 May 2024

Abstract

:
Lung cancer remains a formidable global health challenge, necessitating the exploration of innovative diagnostic approaches for early detection. This review paper delves into the burgeoning field of exhaled breath analysis using electronic nose (e-nose) technology for the identification of volatile organic compounds (VOCs) as potential biomarkers for lung cancer diagnosis. An electronic nose inspired by the human olfactory system comprises an array of sensors that can detect and differentiate complex odor profiles. This paper elucidates the principles behind e-nose technology and its application in capturing the unique VOC signatures present in exhaled breath, which serve as indicators of underlying physiological conditions. A significant portion of this review is dedicated to elucidating the methodology and advancements in e-nose-based VOC analysis, providing insights into the potential of this non-invasive approach for disease diagnosis. The exploration extends beyond general applications to specifically spotlight the utilization of e-nose technology in the realm of early lung cancer detection. E-nose-based disease diagnosis, and more specifically, lung cancer detection, is discussed in detail, with an emphasis on the recent studies and advancements. The potential of VOC profiling as a reliable and early diagnostic tool for lung cancer is explored, addressing both the promises and challenges associated with this cutting-edge approach. This comprehensive review amalgamates the current state of knowledge in the field, offering a roadmap for future research opportunities and the realization of e-nose technology’s promise in revolutionizing lung cancer diagnosis.

Supplementary Materials

The presentation material of this work is available online at https://www.mdpi.com/article/10.3390/proceedings2024100023/s1.

Author Contributions

Conceptualization, V.A.B.; methodology, software, validation, and formal analysis, V.A.B. and S.T.; investigation, V.A.B.; data curation, V.A.B. and S.T.; writing—original draft preparation, V.A.B.; writing—review and editing, V.A.B. and S.T.; visualization, supervision, project administration, and funding acquisition, V.A.B. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Not applicable.

Conflicts of Interest

The authors declare no conflict of interest.
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Share and Cite

MDPI and ACS Style

Binson, V.A.; Thomas, S. Unveiling the Smell of Health: E-Nose-Based Volatile Organic Compound Analysis of Exhaled Breath in Early Lung Cancer Detection. Proceedings 2024, 100, 23. https://doi.org/10.3390/proceedings2024100023

AMA Style

Binson VA, Thomas S. Unveiling the Smell of Health: E-Nose-Based Volatile Organic Compound Analysis of Exhaled Breath in Early Lung Cancer Detection. Proceedings. 2024; 100(1):23. https://doi.org/10.3390/proceedings2024100023

Chicago/Turabian Style

Binson, V. A., and Sania Thomas. 2024. "Unveiling the Smell of Health: E-Nose-Based Volatile Organic Compound Analysis of Exhaled Breath in Early Lung Cancer Detection" Proceedings 100, no. 1: 23. https://doi.org/10.3390/proceedings2024100023

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