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Journal of Imaging, Volume 7, Issue 4
April 2021 - 14 articles
Cover Story: Beyond well-established diagnostic imaging applications, ultrasounds are currently emerging in clinical practice as a noninvasive technology for therapy: temperature inside target solid tumors can be increased, thus leading to apoptosis/necrosis of neoplastic tissues.
Patient safety during magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatments was investigated by performing experiments in a tissue-mimicking phantom, as well as in ex vivo skin samples, to promptly identify unwanted temperature rises.
MR images were analyzed using classical proton resonance frequency (PRF) shift and referenceless thermometry methods for estimating temperature variations. Results were compared against interferometric optical fiber measurements.
Temperature increases during the treatment were not accurately detected by MR-based referenceless thermometry methods, and more sensitive measurement systems, such as optical fibers, would be required.
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J. Imaging - ISSN 2313-433X