In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria

Lefahal, Mostefa; Zaabat, Nabila; Ayad, Radia; Makhloufi, El Hani; Djarri, Lakhdar; Benahmed, Merzoug; Laouer, Hocine; Nieto, Gema; Akkal, Salah

doi:10.3390/medicines5020026

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In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria

¹,

¹,

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¹,

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²,

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^4,*

and

Salah Akkal

^1,*

Valorization of Natural Resources, Bioactive Molecules and Biological Analysis Unit, Department of Chemistry, University of Mentouri Constantine, Constantine 25000, Algeria

Department of Chemistry, Faculty of Science, University of Tebessa, Tebessa 12000, Algeria

Laboratory of Natural Biological Resources Valorization, Faculty of Sciences, University of Setif, Setif 19000, Algeria

⁴

Department of Food Technology, Nutrition and Food Science, Faculty of veterinary Sciences, University of Murcia, Campus de Espinardo, Espinardo, 30100 Murcia, Spain

Authors to whom correspondence should be addressed.

Medicines 2018, 5(2), 26; https://doi.org/10.3390/medicines5020026

Received: 17 February 2018 / Revised: 19 March 2018 / Accepted: 21 March 2018 / Published: 22 March 2018

(This article belongs to the Special Issue Medicinal Plants and Foods)

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Abstract

Background: Capnophyllum peregrinum (L.) Lange (Apiaceae) is the unique taxon of capnophyllum genus in Algerian flora. It has never been investigated in regards to its total phenolic and flavonoid contents and antioxidant and photoprotective activities. Methods: C. peregrinum aerial parts extracted with absolute methanol. The total flavonoid and phenolic contents of the extract were evaluated to determine their correlation with the antioxidant and photoprotective activities of the extract. Results: The methanolic extract demonstrated a significant amount of phenolics and flavonoids (74.06 ± 1.23 mg GAE/g, 44.09 ± 2.13 mg QE/g, respectively) and exhibited good antioxidant activity in different systems, especially in 1,1-Diphenyl-2-picrylhydrazyl (DPPH), reducing power and total antioxidant capacity assays. Furthermore the extract showed high photoprotective activity with the sun protection factor (SPF) value = 35.21 ± 0.18. Conclusions: The results of the present study show, that the methanolic extract could be used as a natural sunscreen in pharmaceutics or cosmetic formulations and as a valuable source of natural antioxidants. View Full-Text

Keywords: Capnophyllum peregrinum; antioxidant activity; photoprotective activity

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MDPI and ACS Style

Lefahal, M.; Zaabat, N.; Ayad, R.; Makhloufi, E.H.; Djarri, L.; Benahmed, M.; Laouer, H.; Nieto, G.; Akkal, S. In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria. Medicines 2018, 5, 26. https://doi.org/10.3390/medicines5020026

AMA Style

Lefahal M, Zaabat N, Ayad R, Makhloufi EH, Djarri L, Benahmed M, Laouer H, Nieto G, Akkal S. In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria. Medicines. 2018; 5(2):26. https://doi.org/10.3390/medicines5020026

Chicago/Turabian Style

Lefahal, Mostefa, Nabila Zaabat, Radia Ayad, El H. Makhloufi, Lakhdar Djarri, Merzoug Benahmed, Hocine Laouer, Gema Nieto, and Salah Akkal. 2018. "In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria" Medicines 5, no. 2: 26. https://doi.org/10.3390/medicines5020026

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In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria

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