Next Article in Journal
Acknowledgement to Reviewers of Medicines in 2017
Next Article in Special Issue
In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria
Previous Article in Journal / Special Issue
Hydroxytyrosol: Health Benefits and Use as Functional Ingredient in Meat
Article Menu
Issue 1 (March) cover image

Export Article

Open AccessCommunication
Medicines 2018, 5(1), 14; https://doi.org/10.3390/medicines5010014

Characterisation of Polyphenol-Containing Extracts from Stachys mucronata and Evaluation of Their Antiradical Activity

1
Food Quality & Chemistry of Natural Products, Mediterranean Agronomic Institute of Chania (M.A.I.Ch.), International Centre for Advanced Mediterranean Agronomic Studies (CIHEAM), P.O. Box 85, 73100 Chania, Greece
2
Department of Food Technology, Technological Educational Institute (T.E.I.) of Thessaly, N. Temponera Street, 43100 Karditsa, Greece
*
Author to whom correspondence should be addressed.
Received: 9 January 2018 / Revised: 20 January 2018 / Accepted: 26 January 2018 / Published: 27 January 2018
(This article belongs to the Special Issue Medicinal Plants and Foods)
Full-Text   |   PDF [1679 KB, uploaded 27 January 2018]   |  

Abstract

Background: The aromatic plant Stachys mucronata (Lamiaceae) is endemic to the island of Crete (southern Greece), but as opposed to other native Greek members of this family, this species has never been investigated in the past with regard to its polyphenolic composition and antioxidant potency. Methods: Aerial parts of S. mucronata were exhaustively extracted and partly fractionated through partition, using n-butanol and dichloromethane. Results: Following an initial examination, which consisted of estimating the total polyphenol content and the antiradical activity, the n-butanol extract was found to be by far the richest in polyphenols, exhibiting much stronger antiradical activity compared with the dichloromethane counterpart. On this basis, the n-butanol extract was analysed by liquid chromatography-diode array-mass spectrometry, to tentatively characterise the principal polyphenolic components, which were shown to be flavonol but mainly flavone derivatives. Conclusions: The most potent radical-scavenging compounds were detected in the n-butanol fraction of the extracts, suggesting that the most active antioxidants in S. mucronate are relatively polar. The analyses suggested the major constituents to be derivatives of the flavone luteolin, accompanied by apigenin analogues, as well as flavonol glycosides and chlorogenate conjugates. View Full-Text
Keywords: antioxidants; Lamiaceae; polyphenols; Stachys mucronata antioxidants; Lamiaceae; polyphenols; Stachys mucronata
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Grigorakis, S.; Makris, D.P. Characterisation of Polyphenol-Containing Extracts from Stachys mucronata and Evaluation of Their Antiradical Activity. Medicines 2018, 5, 14.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Medicines EISSN 2305-6320 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top