The Optimization of the Oiling Bath Cosmetic Composition Containing Rapeseed Phospholipids and Grapeseed Oil by the Full Factorial Design
Abstract
:1. Introduction
2. Experimental Section
2.1. Chemicals and Materials
2.2. Methods
2.2.1. Choice of Solvent
Ingredient | Quantity (g) | Function |
---|---|---|
Grapeseed oil | 76.0 | SC coating |
LESF | 10.0 | SC coating/surfactant |
Anhydrous ethanol | 10.0 | Solvent |
Polysorbate a | 2.0 | Surfactant |
Ascorbyl palmitate | 1.0 | Antioxidant |
Peppermint oil | 1.0 | Fragrance |
2.2.2. Choice of Nonionic Emulsifier
2.2.3. Oiling Bath Composition and Preparation
2.2.4. Dispersion Degree Determination of Bath Emulsions
2.2.5. Optimization of the Oiling Bath Composition
Variables (zj) | L (g) | E (g) | P (g) |
---|---|---|---|
Code symbols | x1 | x2 | x3 |
Basic level (zj0) | 10 | 10 | 2 |
Interval of variation (Δzj) | 2 | 5 | 1 |
Higher level (+) | 12 | 15 | 3 |
Lower level (−) | 8 | 5 | 1 |
3. Results and Discussion
Experiment Number | L (g) | E (g) | P (g) |
---|---|---|---|
1 | 12 | 15 | 3 |
2 | 12 | 15 | 1 |
3 | 12 | 5 | 3 |
4 | 12 | 5 | 1 |
5 | 8 | 15 | 3 |
6 | 8 | 15 | 1 |
7 | 8 | 5 | 3 |
8 | 8 | 5 | 1 |
9 a | 10 | 10 | 2 |
Experiment Number | Standardized Variables Level | Dispersion Degree DD × 10−5 (cm−1) | |||||||
---|---|---|---|---|---|---|---|---|---|
x0 | x1 | x2 | x3 | x 1x2 | x1x3 | x2x3 | x1x2x3 | ||
1 | +1 | +1 | +1 | +1 | +1 | +1 | +1 | +1 | 2.722 |
2 | +1 | +1 | +1 | −1 | +1 | −1 | −1 | −1 | 2.905 |
3 | +1 | +1 | −1 | +1 | −1 | +1 | −1 | −1 | 3.760 |
4 | +1 | +1 | −1 | −1 | −1 | −1 | +1 | +1 | 3.281 |
5 | +1 | −1 | +1 | +1 | −1 | −1 | +1 | −1 | 4.323 |
6 | +1 | −1 | +1 | −1 | −1 | +1 | −1 | +1 | 3.868 |
7 | +1 | −1 | −1 | +1 | +1 | −1 | −1 | +1 | 2.843 |
8 | +1 | −1 | −1 | −1 | +1 | +1 | +1 | −1 | 3.489 |
Symbol of Regression Equation Coefficient | Regression Coefficient Value | Error Estimation Value |
---|---|---|
b0 | 3.399 a | 99.970 |
b1 | −0.232 a | 6.824 |
b2 | 0.056 | 1.635 |
b3 | 0.013 | 0.382 |
b12 | −0.409 a | 12.029 |
b13 | 0.061 | 1.794 |
b23 | 0.055 | 1.618 |
b123 | −0.220 a | 6.471 |
- s2—variance of the results of experiments on the basic level;
- s2res—residual variance:
Optimization Result | Value |
---|---|
Calculated response function from Equation (10) (emulsion dispersion degree DD × 10−5 cm−1) | 5.474 |
Emulsion dispersion degree from control experiment (emulsion dispersion degree DD × 10−5 cm−1) | 5.001 |
Difference between calculated and control values (%) | 8.64 |
Maximum value obtained in the primary experiments (emulsion dispersion degree DD × 10−5 cm−1) | 3.096 |
Increase in emulsion dispersion degree after optimization (%) | 61.53 |
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Górecki, M.; Kurek-Górecka, A.; Sosada, M.; Pasker, B.; Pająk, M.; Fraś, P. The Optimization of the Oiling Bath Cosmetic Composition Containing Rapeseed Phospholipids and Grapeseed Oil by the Full Factorial Design. Cosmetics 2015, 2, 127-135. https://doi.org/10.3390/cosmetics2020127
Górecki M, Kurek-Górecka A, Sosada M, Pasker B, Pająk M, Fraś P. The Optimization of the Oiling Bath Cosmetic Composition Containing Rapeseed Phospholipids and Grapeseed Oil by the Full Factorial Design. Cosmetics. 2015; 2(2):127-135. https://doi.org/10.3390/cosmetics2020127
Chicago/Turabian StyleGórecki, Michał, Anna Kurek-Górecka, Marian Sosada, Beata Pasker, Monika Pająk, and Paweł Fraś. 2015. "The Optimization of the Oiling Bath Cosmetic Composition Containing Rapeseed Phospholipids and Grapeseed Oil by the Full Factorial Design" Cosmetics 2, no. 2: 127-135. https://doi.org/10.3390/cosmetics2020127