Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device
Abstract
:1. Introduction
2. Material and Methods
2.1. Participants
2.2. Study Protocol
2.3. MSOT Image Acquisition and Data Analysis
3. Results
4. Discussion
- MSOT differentiates between distinct types of vessels including lymphatics
- MSOT detects lymphatic vessels in areas of dermal backflow
- MSOT provides images in real-time with high spatiotemporal resolution
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Patient Number | Gender | Age | Primary or Secondary Lymphedema | Prior Cancer Treatment | Localization of Lymphedema | Lymphedema Staging | ICG Patterns on Lymphography | MSOT Detection of Lymphatic Vessels | MSOT Detection of Veins |
---|---|---|---|---|---|---|---|---|---|
1 * | F | 63 | Secondary | Breast | Left arm | 4 | L/SD/D | Yes | Yes |
2 | F | 72 | Secondary | Breast | Right arm | 4 | D | No | Yes |
3 | M | 66 | Secondary | Prostate | Left leg | 3 | L/SD | No (hair) | Yes |
4 | F | 49 | Secondary | Cervix | Left leg | 3 | L/SD | Yes | Yes |
5 | f | 74 | Secondary | Breast | Right arm | 4 | L/D | Yes | Yes |
6 | M | 63 | Secondary | Prostate | Left leg | 3 | L/SD/D | Yes | Yes |
7 | M | 73 | Primary | Left leg | 3 | D # | Yes | Yes | |
8 | F | 43 | Secondary | Cervix | Right leg | 4 | D | No | Yes |
9 | F | 72 | Secondary | Endometrial | Left leg | 4 | D | Yes | Yes |
10 | F | 54 | Secondary | Cervix | Left leg | 4 | L/SD/D | Yes | Yes |
11 | F | 60 | Primary | Left leg | 4 | D # | Yes | Yes |
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Giacalone, G.; Yamamoto, T.; Belva, F.; Hayashi, A. Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device. J. Clin. Med. 2020, 9, 815. https://doi.org/10.3390/jcm9030815
Giacalone G, Yamamoto T, Belva F, Hayashi A. Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device. Journal of Clinical Medicine. 2020; 9(3):815. https://doi.org/10.3390/jcm9030815
Chicago/Turabian StyleGiacalone, Guido, Takumi Yamamoto, Florence Belva, and Akitatsu Hayashi. 2020. "Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device" Journal of Clinical Medicine 9, no. 3: 815. https://doi.org/10.3390/jcm9030815