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Texas Sour Orange Juice Used in Scaffolds for Tissue Engineering

Department of Mechanical Engineering, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA
Department of Biology, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA
Author to whom correspondence should be addressed.
Membranes 2018, 8(3), 38;
Received: 31 May 2018 / Revised: 23 June 2018 / Accepted: 2 July 2018 / Published: 4 July 2018
(This article belongs to the Special Issue Electrospun Nanofiber Membranes: Advances and Applications)
Fine fibers of polyhydroxybutyrate (PHB), a biopolymer, were developed via a centrifugal spinning technique. The developed fibers have an average diameter of 1.8 µm. Texas sour orange juice (SOJ) was applied as a natural antibacterial agent and infiltrated within the fibrous membranes. The antibacterial activity against common Gram-positive and Gram-negative bacteria (Staphylococcus aureus and Escherichia coli, respectively) was evaluated as well as cell adhesion and viability. The PHB/SOJ scaffolds showed antibacterial activity of up to 152% and 71% against S. aureus and E. coli, respectively. The cell studies revealed a suitable environment for cell growth and cell attachment. The outcome of this study opens up new opportunities for fabrication of fibrous materials for biomedical applications having multifunctional properties while using natural agents. View Full-Text
Keywords: centrifugal spinning; polyhydroxybutyrate; membrane; biomedical centrifugal spinning; polyhydroxybutyrate; membrane; biomedical
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MDPI and ACS Style

Akia, M.; Salinas, N.; Rodriguez, C.; Gilkerson, R.; Materon, L.; Lozano, K. Texas Sour Orange Juice Used in Scaffolds for Tissue Engineering. Membranes 2018, 8, 38.

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