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Alkali Treatment of Anodized Titanium Alloys Affects Cytocompatibility

1
Faculty of Chemistry, Silesian University of Technology, B. Krzywoustego Street 6, 44-100 Gliwice, Poland
2
Laboratory of Virology, Institute of Immunology and Experimental Therapy (IIET), Polish Academy of Sciences, Rudolfa Weigla Street 12, 53-114 Wroclaw, Poland
3
USI, Unit of Nanostructural Biointeractions, Laboratory of Virology, Institute of Immunology and Experimental Therapy (IIET), Polish Academy of Sciences, Rudolfa Weigla Street 12, 53-114 Wroclaw, Poland
*
Authors to whom correspondence should be addressed.
Metals 2018, 8(1), 29; https://doi.org/10.3390/met8010029
Received: 31 October 2017 / Revised: 27 December 2017 / Accepted: 28 December 2017 / Published: 3 January 2018
(This article belongs to the Special Issue Plasma Electrolytic Oxidation)
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Abstract

In this paper, the surface modification of titanium alloys Ti-15Mo, Ti-13Nb-13Zr, and Ti-6Al-7Nb is presented as a material for dental implants. The conditions of the plasma electrolytic oxidation process and alkali treatment were designed in this way to enhance the biological properties of the surface of promising Ti alloys. The differences in their surface morphology and, consequently, in their biological properties were discussed. The bioactivity of the samples was examined in vitro using simulated body fluid, and Saos-2 osteoblast cells. On all the samples, characteristic apatite particles were formed. However, compared to as-ground, natively-oxidized bare alloys, the plasma electrolytic oxidation (PEO)-modified surface of the Ti-13Nb-13Zr alloy showed the highest cytocompatibility for Saos-2 osteoblast cells, and a beneficial gain of cytocompatibility was also achieved in the treated sample of Ti-6Al-7Nb. In contrast, the modification of the Ti-15Mo alloy did not influence the adhesion and proliferation of osteoblast cells. View Full-Text
Keywords: titanium alloys; anodization; alkali treatment; cytocompatibility titanium alloys; anodization; alkali treatment; cytocompatibility
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Kazek-Kęsik, A.; Leśniak, K.; Orzechowska, B.U.; Drab, M.; Wiśniewska, A.; Simka, W. Alkali Treatment of Anodized Titanium Alloys Affects Cytocompatibility. Metals 2018, 8, 29.

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