Table of Contents
Antibodies, Volume 9, Issue 1 (March 2020) – 6 articles
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Cover Story (view full-size image) Hybridoma screening is a tedious and challenging task. Several pitfalls can lead to false [...] Read more. Hybridoma screening is a tedious and challenging task. Several pitfalls can lead to false positives, which might be identified as poor quality, but not before an in-depth validation has been performed. Hence, the best clones must be identified as early as possible, ideally in the first screening step. This novel, microarray-based method enables the user to screen a vast number of clones with a very selective and sensitive assay. Only high quality antibodies are detected as positive. One or several inhibition assays can be performed in parallel that directly confirm the utility of the clones in competitive immunoassays. View this paper.