Identification of Novel Genomic Associations and Gene Candidates for Grain Starch Content in Sorghum
Round 1
Reviewer 1 Report
The manuscript is well structured and written. I have only few minor comments:
L 131: Write „HSP90-6“ not „HSP 90-6“ L
162: Please revise sentence, “…,we extracted the SNPs from within the genes from the network and ...“
L 165: You may write „HSP70“ instead of „heat shock protein 70“, HSP was explained earlier (L 9) and HSP70 already mentioned (L 154).
L 195-201: I am fine with the comments regarding false positives but I am not really convinced regarding false negatives. I could imagine there are still many unidentified loci with an effect on starch content in the population.
Author Response
Thank you for you reviews. The comments will be incorporated into the revised manuscript.
Reviewer 2 Report
Please find comments in the attached file.
Comments for author File: Comments.pdf
Author Response
Dear Reviewer,
Thank you for your comments and suggestions. We have tried our best to address them. Please see the detailed response in the document attached.
Best,
Sirjan Sapkota
Author Response File: Author Response.docx
Round 2
Reviewer 2 Report
Please find comments in the attached file.
Comments for author File: Comments.pdf
Author Response
Dear reviewer,
Thank you for your suggestions. We hope we have attended to all of your concerns. Please find the detailed response attached.
Thank you,
Sirjan
Author Response File: Author Response.pdf
Round 3
Reviewer 2 Report
This revised version is substantially improved. The questions I had on the previous versions are now cleared, and the M&M is much better and possible to follow and understand. I have carefully revised the manuscript along with the comments made in the previous round, and I believe that this version is almost good for publication, once the minor comment below is addressed.
Minor
L155-156: It is not very clear to me how is it that the BSLMM estimates the \alpha_i and \beta_i to explain the small and large SNP effects.