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Review

Engineered Bioactive Polymeric Surfaces by Radiation Induced Graft Copolymerization: Strategies and Applications

1
Advanced Materials Research Group, Center of Hydrogen Energy, Universiti Teknologi Malaysia, Jalan Sultan Yahya Putra, Kuala Lumpur 54100, Malaysia
2
Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia
3
Bioengineering Laboratory, Department of Textile Technology, Indian Institute of Technology, New Delhi 110016, India
4
Radiation Processing Technology Division, Malaysian Nuclear Agency, Kajang 43000, Malaysia
*
Author to whom correspondence should be addressed.
Academic Editor: Alina Sionkowska
Polymers 2021, 13(18), 3102; https://doi.org/10.3390/polym13183102
Received: 10 August 2021 / Revised: 3 September 2021 / Accepted: 5 September 2021 / Published: 15 September 2021
(This article belongs to the Section Polymer Chemistry)
The interest in developing antimicrobial surfaces is currently surging with the rise in global infectious disease events. Radiation-induced graft copolymerization (RIGC) is a powerful technique enabling permanent tunable and desired surface modifications imparting antimicrobial properties to polymer substrates to prevent disease transmission and provide safer biomaterials and healthcare products. This review aims to provide a broader perspective of the progress taking place in strategies for designing various antimicrobial polymeric surfaces using RIGC methods and their applications in medical devices, healthcare, textile, tissue engineering and food packing. Particularly, the use of UV, plasma, electron beam (EB) and γ-rays for biocides covalent immobilization to various polymers surfaces including nonwoven fabrics, films, nanofibers, nanocomposites, catheters, sutures, wound dressing patches and contact lenses is reviewed. The different strategies to enhance the grafted antimicrobial properties are discussed with an emphasis on the emerging approach of in-situ formation of metal nanoparticles (NPs) in radiation grafted substrates. The current applications of the polymers with antimicrobial surfaces are discussed together with their future research directions. It is expected that this review would attract attention of researchers and scientists to realize the merits of RIGC in developing timely, necessary antimicrobial materials to mitigate the fast-growing microbial activities and promote hygienic lifestyles. View Full-Text
Keywords: antimicrobial polymer surfaces; radiation induced graft copolymerization; protective fabrics; biomedical devices; tissue engineering materials; food packing films antimicrobial polymer surfaces; radiation induced graft copolymerization; protective fabrics; biomedical devices; tissue engineering materials; food packing films
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MDPI and ACS Style

Nasef, M.M.; Gupta, B.; Shameli, K.; Verma, C.; Ali, R.R.; Ting, T.M. Engineered Bioactive Polymeric Surfaces by Radiation Induced Graft Copolymerization: Strategies and Applications. Polymers 2021, 13, 3102. https://doi.org/10.3390/polym13183102

AMA Style

Nasef MM, Gupta B, Shameli K, Verma C, Ali RR, Ting TM. Engineered Bioactive Polymeric Surfaces by Radiation Induced Graft Copolymerization: Strategies and Applications. Polymers. 2021; 13(18):3102. https://doi.org/10.3390/polym13183102

Chicago/Turabian Style

Nasef, Mohamed Mahmoud, Bhuvanesh Gupta, Kamyar Shameli, Chetna Verma, Roshafima Rasit Ali, and Teo Ming Ting. 2021. "Engineered Bioactive Polymeric Surfaces by Radiation Induced Graft Copolymerization: Strategies and Applications" Polymers 13, no. 18: 3102. https://doi.org/10.3390/polym13183102

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