Next Article in Journal
Analysis of Eating Habits and Body Composition of Young Adult Poles
Next Article in Special Issue
Lactate Threshold Training Program on Patients with Multiple Sclerosis: A Multidisciplinary Approach
Previous Article in Journal
Nut Allergy: Clinical and Allergological Features in Italian Children
Previous Article in Special Issue
The Role of Nutritional Lifestyle and Physical Activity in Multiple Sclerosis Pathogenesis and Management: A Narrative Review
Review

Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

1
Geriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, Italy
2
Faculty of Medicine and Surgery, University of Enna “Kore”, 94100 Enna, Italy
3
Department of Biomedicine, Neuroscience, and Advanced Diagnostics, University of Palermo, 90100 Palermo, Italy
4
UOC of Neurology, University Hospital “Paolo Giaccone”, 90100 Palermo, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Panteleimon Giannakopoulos
Nutrients 2021, 13(11), 4080; https://doi.org/10.3390/nu13114080
Received: 17 September 2021 / Revised: 25 October 2021 / Accepted: 27 October 2021 / Published: 15 November 2021
Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical activity. In the next decades, a rise in dementia cases is expected due largely to the aging of the world population. There are no hitherto effective pharmaceutical therapies to treat age-associated cognitive impairment and dementia, which underscores the crucial role of prevention. A relationship among diet, physical activity, and other lifestyle factors with cognitive function has been intensively studied with mounting evidence supporting the role of these determinants in the development of cognitive decline and dementia, which is a chief cause of disability globally. Several dietary patterns, foods, and nutrients have been investigated in this regard, with some encouraging and other disappointing results. This review presents the current evidence for the effects of dietary patterns, dietary components, some supplements, physical activity, sleep patterns, and social engagement on the prevention or delay of the onset of age-related cognitive decline and dementia. View Full-Text
Keywords: cognitive decline; Alzheimer; dementia; aging; nutrition; physical activity; exercise; diet; sleep; socialization; oxidative stress; inflammation cognitive decline; Alzheimer; dementia; aging; nutrition; physical activity; exercise; diet; sleep; socialization; oxidative stress; inflammation
MDPI and ACS Style

Dominguez, L.J.; Veronese, N.; Vernuccio, L.; Catanese, G.; Inzerillo, F.; Salemi, G.; Barbagallo, M. Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia. Nutrients 2021, 13, 4080. https://doi.org/10.3390/nu13114080

AMA Style

Dominguez LJ, Veronese N, Vernuccio L, Catanese G, Inzerillo F, Salemi G, Barbagallo M. Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia. Nutrients. 2021; 13(11):4080. https://doi.org/10.3390/nu13114080

Chicago/Turabian Style

Dominguez, Ligia J., Nicola Veronese, Laura Vernuccio, Giuseppina Catanese, Flora Inzerillo, Giuseppe Salemi, and Mario Barbagallo. 2021. "Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia" Nutrients 13, no. 11: 4080. https://doi.org/10.3390/nu13114080

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop