Next Article in Journal
Skipping Breakfast for 6 Days Delayed the Circadian Rhythm of the Body Temperature without Altering Clock Gene Expression in Human Leukocytes
Next Article in Special Issue
Moderators of the Impact of (Poly)Phenols Interventions on Psychomotor Functions and BDNF: Insights from Subgroup Analysis and Meta-Regression
Previous Article in Journal
L-Carnitine’s Effect on the Biomarkers of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Previous Article in Special Issue
The Impact of a Polyphenol-Rich Extract from the Berries of Aronia melanocarpa L. on Collagen Metabolism in the Liver: A Study in an In Vivo Model of Human Environmental Exposure to Cadmium
Review

Chemical Composition, Bioactivity and Safety Aspects of Kuding Tea—From Beverage to Herbal Extract

Institute of Human Nutrition and Food Science, University of Kiel, Hermann-Rodewald-Strasse 6, 24118 Kiel, Germany
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(9), 2796; https://doi.org/10.3390/nu12092796
Received: 11 August 2020 / Revised: 9 September 2020 / Accepted: 10 September 2020 / Published: 12 September 2020
(This article belongs to the Special Issue Dietary (Poly)Phenols and Health)
Kuding tea (KT) is a bitter-tasting herbal tea that has been commonly used in traditional Chinese medicine (TCM). The large-leaved Ku-Ding-Cha (Aquifoliaceae) is composed of its representative species Ilex latifolia Thunb and Ilex kudingcha C.J. Tseng. Because of its potential lipid-lowering, body weight-reducing and blood-glucose-lowering properties, KT has increasingly been recognised for its importance over the past several decades. KT is no longer used only as a beverage, and various extraction methods have been applied to obtain aqueous and ethanolic KT extracts (KTE) or their fractions, which could potentially be used as dietary supplements. The major bioactive components of KT are triterpene saponins and polyphenols, but the composition of KT differs substantially between and among the different KT species. This in turn might affect the physiological effects of KT. KT exhibits antiobesity properties, possibly partly by affecting the intestinal microbiota. In addition, KT may mediate putative antioxidative, anti-inflammatory and anticancer activities. However, there is evidence that high KTE supplementation can adversely affect liver metabolism. The physiological relevance of KT in humans remains rather unclear since the potential health benefits of KT and its constituents reviewed here are mainly derived on the basis of in vitro and animal studies. View Full-Text
Keywords: kuding tea; kudingcha; Ilex; herbal drug; extract; bioactivity; safety kuding tea; kudingcha; Ilex; herbal drug; extract; bioactivity; safety
Show Figures

Figure 1

MDPI and ACS Style

Wüpper, S.; Lüersen, K.; Rimbach, G. Chemical Composition, Bioactivity and Safety Aspects of Kuding Tea—From Beverage to Herbal Extract. Nutrients 2020, 12, 2796. https://doi.org/10.3390/nu12092796

AMA Style

Wüpper S, Lüersen K, Rimbach G. Chemical Composition, Bioactivity and Safety Aspects of Kuding Tea—From Beverage to Herbal Extract. Nutrients. 2020; 12(9):2796. https://doi.org/10.3390/nu12092796

Chicago/Turabian Style

Wüpper, Svenja, Kai Lüersen, and Gerald Rimbach. 2020. "Chemical Composition, Bioactivity and Safety Aspects of Kuding Tea—From Beverage to Herbal Extract" Nutrients 12, no. 9: 2796. https://doi.org/10.3390/nu12092796

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop