Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999–2014
1
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Univesrsitário São João, 4200 Porto, Portugal
2
CINTESIS—Centre for Health Technologies and Information Systems Research, Faculty of Medicine, University of Porto, 4200 Porto, Portugal
3
Department of Surgery and Physiology, Cardiovascular Research Centre, Faculty of Medicine, University of Porto, 4200 Porto, Portugal
4
Health Information and Decision Sciences Department, Faculty of Medicine, Porto University, 4200 Porto, Portugal
5
I3S—Instituto de Investigação e Inovação em Saúde, Faculty of Medicine, University of Porto, 4200 Porto, Portugal
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(7), 1482; https://doi.org/10.3390/nu11071482
Received: 24 May 2019
/
Revised: 25 June 2019
/
Accepted: 26 June 2019
/
Published: 28 June 2019
(This article belongs to the Special Issue Nutrition, Microbiota and Noncommunicable Diseases)
Gut microbiota dysbiosis has been recognized as having key importance in obesity- and metabolic-related diseases. Although there is increasing evidence of the potential benefits induced by probiotics in metabolic disturbances, there is a lack of large cross-sectional studies to assess population-based prevalence of probiotic intake and metabolic diseases. Our aim was to evaluate the association of probiotic ingestion with obesity, type 2 diabetes, hypertension, and dyslipidemia. A cross-sectional study was designed using data from the National Health and Nutrition Examination Survey (NHANES), 1999–2014. Probiotic ingestion was considered when a subject reported consumption of yogurt or a probiotic supplement during the 24-h dietary recall or during the Dietary Supplement Use 30-Day questionnaire. We included 38,802 adults and 13.1% reported probiotic ingestion. The prevalence of obesity and hypertension was lower in the probiotic group (obesity-adjusted Odds Ratio (OR): 0.84, 95% CI 0.76–0.92, p < 0.001; hypertension-adjusted OR: 0.79, 95% CI 0.71–0.88, p < 0.001). Accordingly, even after analytic adjustments, body mass index (BMI) was significantly lower in the probiotic group, as were systolic and diastolic blood pressure and triglycerides; high-density lipoprotein (HDL) was significantly higher in the probiotic group for the adjusted model. In this large-scale study, ingestion of probiotic supplements or yogurt was associated with a lower prevalence of obesity and hypertension.
View Full-Text
Keywords:
intestinal microbiota; probiotics; nutrients
▼
Show Figures
Figure 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
- Supplementary File 1:
PDF-Document (PDF, 371 KiB)
MDPI and ACS Style
Lau, E.; Neves, J.S.; Ferreira-Magalhães, M.; Carvalho, D.; Freitas, P. Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999–2014. Nutrients 2019, 11, 1482. https://doi.org/10.3390/nu11071482
AMA Style
Lau E, Neves JS, Ferreira-Magalhães M, Carvalho D, Freitas P. Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999–2014. Nutrients. 2019; 11(7):1482. https://doi.org/10.3390/nu11071482
Chicago/Turabian StyleLau, Eva, João S. Neves, Manuel Ferreira-Magalhães, Davide Carvalho, and Paula Freitas. 2019. "Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999–2014" Nutrients 11, no. 7: 1482. https://doi.org/10.3390/nu11071482
Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
