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Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide

Food Science & Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
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Nutrients 2019, 11(2), 295; https://doi.org/10.3390/nu11020295
Received: 21 December 2018 / Revised: 24 January 2019 / Accepted: 28 January 2019 / Published: 30 January 2019
(This article belongs to the Special Issue Dietary Bioactive Compounds and Human Health and Disease)
Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H2S), an endogenous, gaseous, signaling transmitter, has also been shown to be involved in the regulation of inflammation. Recent studies have shown that sulfur-containing compounds from garlic have beneficial effects in attenuating outcomes associated with cardiovascular disease and inflammation by a mechanism that may be related to the H2S signaling pathway. In this review, we summarize the main functions of glutathione (GSH), garlic derivatives and H2S and their role in the immune response and impact on health and disease. View Full-Text
Keywords: aged garlic extract; glutathione; hydrogen sulfide; immune response; inflammation aged garlic extract; glutathione; hydrogen sulfide; immune response; inflammation
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Rodrigues, C.; Percival, S.S. Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide. Nutrients 2019, 11, 295.

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