Human Postprandial Nutrient Metabolism and Low-Grade Inflammation: A Narrative Review
1
Department of Endocrinology and Metabolism, Amsterdam University Medical Centers, Location Academic Medical Center (AMC), PO box 22660, 1100 DD Amsterdam, The Netherlands
2
Department of Vascular Medicine, Amsterdam University Medical Centers, Location AMC, 1100 DD Amsterdam, The Netherlands
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(12), 3000; https://doi.org/10.3390/nu11123000
Received: 7 November 2019 / Revised: 3 December 2019 / Accepted: 4 December 2019 / Published: 7 December 2019
(This article belongs to the Special Issue Arthritis and Nutrition: Can Food Be Medicine?)
The importance of the postprandial state has been acknowledged, since hyperglycemia and hyperlipidemia are linked with several chronic systemic low-grade inflammation conditions. Humans spend more than 16 h per day in the postprandial state and the postprandial state is acknowledged as a complex interplay between nutrients, hormones and diet-derived metabolites. The purpose of this review is to provide insight into the physiology of the postprandial inflammatory response, the role of different nutrients, the pro-inflammatory effects of metabolic endotoxemia and the anti-inflammatory effects of bile acids. Moreover, we discuss nutritional strategies that may be linked to the described pathways to modulate the inflammatory component of the postprandial response.
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MDPI and ACS Style
Meessen, E.C.; Warmbrunn, M.V.; Nieuwdorp, M.; Soeters, M.R. Human Postprandial Nutrient Metabolism and Low-Grade Inflammation: A Narrative Review. Nutrients 2019, 11, 3000.
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