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Open AccessArticle

Quality of Life of Celiac Patients in Brazil: Questionnaire Translation, Cultural Adaptation and Validation

1
Interdisciplinary Laboratory of Biosciences and Celiac Disease Research Center, School of Medicine, University of Brasilia, 70910-900 Brasilia, DF, Brazil
2
Post-graduate Program in Health Sciences, School of Health Sciences, University of Brasilia, Brasilia 70910-900, DF, Brazil
3
Department of Internal Medicine I, Klinikum Saarbrücken and Department of Psychosomatic Medicine and Psychotherapy, Technische Universität München, 80333 München, Germany
4
Department of Statistics, University of Brasilia, 70910-900 Brasilia, DF, Brazil
5
Department of Nutrition, School of Health Sciences, University of Brasilia, 70910-900 Brasilia, DF, Brazil
*
Author to whom correspondence should be addressed.
Nutrients 2018, 10(9), 1167; https://doi.org/10.3390/nu10091167
Received: 6 August 2018 / Revised: 16 August 2018 / Accepted: 22 August 2018 / Published: 25 August 2018
(This article belongs to the Special Issue Gluten-Free Diet)
(1) Background: Celiac disease (CD) is a common autoimmune disorder. The manifestations of the disease and the obligatory life-long gluten-free diet (GFD) are associated with the impairment of patients’ quality of life. Therefore, the present study aimed to translate, culturally adapt and validate a celiac disease quality of life (CD-QoL) questionnaire and apply it to a representative number of Brazilian CD patients. (2) Methods: A cross-cultural Brazilian-Portuguese version of the CD-QoL was developed according to revised international guidelines. The questionnaire was administered to 450 celiac patients. The reliability, reproducibility and validity were studied. (3) Results: The Brazilian CD-QoL questionnaire presents valid measures of reproducibility and internal consistency. Early diagnosis is related to higher scores of Brazilian CD-QoL social, sub- and total scale. There was a positive correlation between higher education level and higher QoL. Individuals with partners tend to have a better emotional subscale of QoL. CD-patients who follow a strict GFD have highest QoL scale values. Men scored higher than women on the CD-QoL. All results were statistically significant except for the gastrointestinal subscale. (4) Conclusions: Brazilian CD-QoL allows comparative research between different celiac populations in the world. QoL research will help in the development of effective strategies to improve Brazilian celiac patients’ quality of life. View Full-Text
Keywords: Brazilian CD-QoL; quality of life; celiac disease; questionnaire Brazilian CD-QoL; quality of life; celiac disease; questionnaire
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Pratesi, C.B.; Häuser, W.; Uenishi, R.H.; Selleski, N.; Nakano, E.Y.; Gandolfi, L.; Pratesi, R.; Zandonadi, R.P. Quality of Life of Celiac Patients in Brazil: Questionnaire Translation, Cultural Adaptation and Validation. Nutrients 2018, 10, 1167.

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