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Hematology Reports
Volume 3
Issue 3
10.4081/hr.2011.e27
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

A Case of Chronic Myelogenous Leukemia in Pregnancy Characterized by a Complex Translocation t(9;22;11)(q34;q11.2;q13)

by
Surachit Kumar
,
Mariya Apostolova
and
Paul V. Woolley
*
Department of Medicine, Conemaugh Cancer Care Center, 1020 Franklin St., Johnstown, PA 15905, USA
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2011, 3(3), e27; https://doi.org/10.4081/hr.2011.e27
Submission received: 5 September 2011 / Revised: 24 October 2011 / Accepted: 24 October 2011 / Published: 21 November 2011

Abstract

The management of chronic myelogenous leukemia during pregnancy requires balancing the well-being of the mother with that of the fetus. We report a case of a 26-year-old lady who was diagnosed with chronic myelogenous leukemia (CML) at 15 weeks gestation and who had an atypical chromosome t(9;22;11) (q34;q11.2;q13) translocation. She was observed through the remainder of the pregnancy and the disease remained stable; she delivered a normal boy. Treatment with imatinib mesylate was initiated shortly after delivery and she went into molecular complete remission. We discuss the course of the disease and suggest guidelines for managing pregnancy with respect to the currently available agents imatinib, dasatinib and nilotinib.
Keywords: medicine; hematology; leukemia; CML medicine; hematology; leukemia; CML

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MDPI and ACS Style

Kumar, S.; Apostolova, M.; Woolley, P.V. A Case of Chronic Myelogenous Leukemia in Pregnancy Characterized by a Complex Translocation t(9;22;11)(q34;q11.2;q13). Hematol. Rep. 2011, 3, e27. https://doi.org/10.4081/hr.2011.e27

AMA Style

Kumar S, Apostolova M, Woolley PV. A Case of Chronic Myelogenous Leukemia in Pregnancy Characterized by a Complex Translocation t(9;22;11)(q34;q11.2;q13). Hematology Reports. 2011; 3(3):e27. https://doi.org/10.4081/hr.2011.e27

Chicago/Turabian Style

Kumar, Surachit, Mariya Apostolova, and Paul V. Woolley. 2011. "A Case of Chronic Myelogenous Leukemia in Pregnancy Characterized by a Complex Translocation t(9;22;11)(q34;q11.2;q13)" Hematology Reports 3, no. 3: e27. https://doi.org/10.4081/hr.2011.e27

APA Style

Kumar, S., Apostolova, M., & Woolley, P. V. (2011). A Case of Chronic Myelogenous Leukemia in Pregnancy Characterized by a Complex Translocation t(9;22;11)(q34;q11.2;q13). Hematology Reports, 3(3), e27. https://doi.org/10.4081/hr.2011.e27

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