Cardiovascular Medicine

6 pages, 151 KB

Open AccessArticle

Klinische Effekte der Katheterbasierten Nierennervenablation bei Therapieresistenter Hypertonie

by Isabella Sudano, Amir Pourmand, Renate Schoenenberger-Berzins, Paolo M Suter, Susanne Roas, Christian Templin, Ulf Landmesser, Georg Noll, Edouard Battegay, Paul Erne and Thomas F. Lüscher

Cardiovasc. Med. 2014, 17(1), 8; https://doi.org/10.4414/cvm.2014.00201 - 22 Jan 2014

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Abstract

Clinical effects of catheter-based renal nerve ablation in the case of treatment-resistant hypertension
Background: High blood pressure is one of the most common chronic cardiovascular diseases. Despite a plethora of drugs to lower blood pressure, adequate blood pressure reduction cannot be achieved [...] Read more.

Clinical effects of catheter-based renal nerve ablation in the case of treatment-resistant hypertension
Background: High blood pressure is one of the most common chronic cardiovascular diseases. Despite a plethora of drugs to lower blood pressure, adequate blood pressure reduction cannot be achieved in many patients with high blood pressure. Ablation of the nerves of the renal arteries is used in these patients.
Methods: Renal nerve ablation is a catheter-based, minimally-invasive method which, with the appropriate experience, is relatively easy to carry out, and has already demonstrated very promising results in patients with treatment-resistant hypertension.
Results: The data presented in this article confirm that catheter-based renal nerve ablation, used in 38 patients with treatment-resistant hypertension, is a safe and highly effective method of achieving optimal blood pressure stabilisation.
Conclusion: It remains to be seen whether the promising results of current studies will be confirmed in the long-term progress and lead to a reduction of cardiovascular morbidity and mortality Full article

1 pages, 31 KB

Open AccessEditorial

Schweizerischer Nationalfonds Unterstützt Eine von Basler Forschern Geleitete Nationale Vorhofflimmerkohorte

by David Conen and Stefan Osswald

Cardiovasc. Med. 2014, 17(1), 34; https://doi.org/10.4414/cvm.2014.00207 - 22 Jan 2014

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Abstract

Der Schweizerische Nationalfonds (SNF) hat 2013 erneut Förderbeiträge für longitudinale Kohorten studien ausgeschrieben, welche wichtige volksgesundheitliche Probleme in der Schweiz untersuchen sollen [...] Full article

1 pages, 80 KB

Open AccessEditorial

Herztransplantationsjubiläum am UniversitätsSpital Zürich

by Frank Ruschitzka, Frank Enseleit, Andreas J. Flammer, Markus Wilhelm, Thomas F. Lüscher and Volkmar Falk

Cardiovasc. Med. 2014, 17(1), 32; https://doi.org/10.4414/cvm.2014.00216 - 22 Jan 2014

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Abstract

Am Universitären Herzzentrum des UniversitätsSpitals Zürich (USZ) wurde bei einem Patienten mit schwerer Herzschwäche kürzlich erfolgreich die 400 [...] Full article

1 pages, 33 KB

Open AccessCommunication

Otto Hess Trainee Award 2014 of the Swiss Society of Cardiology

by Karin Guldenfels

Cardiovasc. Med. 2014, 17(1), 31; https://doi.org/10.4414/cvm.2014.00218 - 22 Jan 2014

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Abstract

The Swiss Society of Cardiology (SSC) has created the Otto Hess Trainee Award to recognize and support trainees in cardiology, who have made a significant contribution to research in the field of cardiology at an early stage of their career [...] Full article

5 pages, 150 KB

Open AccessEditorial

Wieviel Marketing Erträgt Die Medizin?

by Thomas F. Lüscher

Cardiovasc. Med. 2014, 17(1), 3; https://doi.org/10.4414/cvm.2014.00212 - 22 Jan 2014

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Abstract

Die ärztliche Praxis ist eine Kunst, kein Handelsgeschäft, eine Berufung, kein Laden; eine Art Erwählung, die das Herz ebenso wie den Kopf fordert [...] Full article

4 pages, 1848 KB

Open AccessInteresting Images

Recurrent Unexplained Syncope in an Adolescent Girl

by Stefano Di Bernado, Tatiana Boulos-Ksontini, Yvan Mivelaz, Niccole Sekarski and Etienne Pruvot

Cardiovasc. Med. 2014, 17(1), 27; https://doi.org/10.4414/cvm.2014.00200 - 22 Jan 2014

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Abstract

This fourteen year-old girl was referred to our outpatient clinic because of recurrent episodes of unexplained syncope [...] Full article

3 pages, 345 KB

Open AccessCase Report

“The Plug and the Bug” – A Case of Coronary Embolism in Bacterial Endocarditis

by Diego Arroyo, Stéphane Cook, Daniel Hayoz and Mario Togni

Cardiovasc. Med. 2014, 17(1), 24; https://doi.org/10.4414/cvm.2014.00203 - 22 Jan 2014

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Abstract

Systemic embolism is a classic complication of infective endocarditis. Coronary involvement and acute myocardial infarction (MI) are rare and increase mortality significantly. Recognising this unusual entity is crucial to provide adequate care. Percutaneous coronary intervention and thrombus aspiration is preferred to thrombolysis, which [...] Read more.

Systemic embolism is a classic complication of infective endocarditis. Coronary involvement and acute myocardial infarction (MI) are rare and increase mortality significantly. Recognising this unusual entity is crucial to provide adequate care. Percutaneous coronary intervention and thrombus aspiration is preferred to thrombolysis, which classically increases intracerebral haemorrhage risk. The present article describes the case of an acute inferior ST-elevated MI due to a Streptococcus salivarius endocarditis in a patient with known bicuspid aortic valve. Full article

3 pages, 197 KB

Open AccessCase Report

To Do or Not to Do? Changing Paradigms: Value of Balloon-Sizing and Left Atrial Appendage Occlusion

by Adrian Attinger-Toller, Philipp K. Haager, Hans Rickli, Thomas F. Lüscher, Ulf Landmesser and Fabian Nietlispach

Cardiovasc. Med. 2014, 17(1), 21; https://doi.org/10.4414/cvm.2014.00202 - 22 Jan 2014

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Abstract

Balloon-sizing of the aortic annulus can be considered the “gold-standard” for annulus-assessment for transcatheter aortic valve implantation (TAVI) – comparable to intraoperative surgical sizing tools. We report a case of an 83 year-old patient referred for TAVI, where CT-angiogram measurements might have prevented [...] Read more.

Balloon-sizing of the aortic annulus can be considered the “gold-standard” for annulus-assessment for transcatheter aortic valve implantation (TAVI) – comparable to intraoperative surgical sizing tools. We report a case of an 83 year-old patient referred for TAVI, where CT-angiogram measurements might have prevented us from performing TAVI and balloon-sizing allowed us to proceed with an excellent final result. Since patients with concomitant atrial fibrillation undergoing TAVI are known to have worse short- and long-term outcomes, left atrial appendage occlusion (LAAO) at the same sitting was successfully performed, to obviate the need for oral anticoagulation. Combining procedures (e.g. TAVI and LAAO) is technically feasible, patient- friendly and should be encouraged where reasonable, despite contrary financial incentives by our health care system. Full article

7 pages, 145 KB

Open AccessArticle

Predicted Value of Serial Measurements of Circulating Vascular Endothelial Growth Factor-1 in Arterial Hypertension Patients After Acute Ischaemic Stroke

by Alexander E. Berezin and Oxana A. Lisovaya

Cardiovasc. Med. 2014, 17(1), 14; https://doi.org/10.4414/cvm.2014.00205 - 22 Jan 2014

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Abstract

The study aim was to investigate the predictive value of the circulating vascular endothelial growth factor-1 (VEGF-1) level measured repeatedly in hypertensive patients after ischaemic stroke. Methods: The study included 102 patients with mild to moderate arterial hypertension, who were evaluated within [...] Read more.

The study aim was to investigate the predictive value of the circulating vascular endothelial growth factor-1 (VEGF-1) level measured repeatedly in hypertensive patients after ischaemic stroke. Methods: The study included 102 patients with mild to moderate arterial hypertension, who were evaluated within a 3-week post ischaemic stroke period. The circulating VEGF-1 level was assessed at baseline and in six months after stroke. Clinical interviews were carried out monthly for a year after stroke. The following are cardiovascular outcomes defined as clinical events: recurrent stroke or transient ischaemic attack (TIA), ischaemic heart disease, sudden death, diabetes mellitus, cardiovascular events, including chronic heart failure and the need for hospital admission for those reasons. Results: The analysis showed an increase in the VEGF-1 concentration, which was obviously associated with the incidence of cardiovascular events within six months after an ischaemic stroke when compared with the individuals without an increase in circulating VEGF-1 levels. Adjusted odds ratio (OR) for the occurrence of cumulative cardiovascular events in hypertensive patients whose VEGF-1 levels were over 403.57 pg/ml at baseline in comparison with OR in those whose VEGF-1 levels were lower, was equal to 4.11 (95% CI = 2.66–7.28; P = 0.001). In six months, the higher circulating VEGF-1 level was over 450.15 pg/ml in the patients who had its level elevated at baseline in comparison with those who had its level lower at baseline, with the higher VEGF-1 level associated with adjusted odds ratio of 5.46 (95% CI = 3.12–7.90; P = 0.001). Defined by serial measurements, adjusted OR for the occurrence of cumulative cardiovascular events in hypertensive patients with increased circulating VEGF-1 level was 6.10 (95% CI = 4.70–8.30, P = 0.001) versus the individuals without such a change in VEGF-1 level. In conclusion, we found that incremented circulating VEGF-1 level was an independent predictor of cumulative cardiovascular events in hypertensive patients within a year after an ischaemic stroke. Full article

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Cardiovasc. Med., Volume 17, Issue 1 (01 2014) – 9 articles

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