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Open AccessArticle

Size-Dependent Properties of Magnetosensitive Polymersomes: Computer Modelling

by Aleksandr Ryzhkov 1,*,† and Yuriy Raikher 2,†
1
Laboratory of Mechanics of Functional Materials, Institute of Continuous Media Mechanics, Ural Branch, Russian Academy of Sciences, 614068 Perm, Russia
2
Laboratory of Physics and Mechanics of Soft Matter, Institute of Continuous Media Mechanics, Ural Branch, Russian Academy of Sciences, 614068 Perm, Russia
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Sensors 2019, 19(23), 5266; https://doi.org/10.3390/s19235266
Received: 22 October 2019 / Revised: 21 November 2019 / Accepted: 26 November 2019 / Published: 29 November 2019
(This article belongs to the Special Issue Biosensors with Magnetic Nanocomponents)
Magnetosensitive polymersomes, which are amphiphilic polymer capsules whose membranes are filled with magnetic nanoparticles, are prospective objects for drug delivery and manipulations with single cells. A molecular dynamics simulation model that is able to render a detailed account on the structure and shape response of a polymersome to an external magnetic field is used to study a dimensional effect: the dependence of the field-induced deformation on the size of this nanoscale object. It is shown that in the material parameter range that resembles realistic conditions, the strain response of smaller polymersomes, against a priori expectations, exceeds that of larger ones. A qualitative explanation for this behavior is proposed. View Full-Text
Keywords: magnetic polymersomes; magnetic vesicles; magnetic nanoparticles; magnetoactive composites; nanocapsules; coarse-grained molecular dynamics; computer simulation magnetic polymersomes; magnetic vesicles; magnetic nanoparticles; magnetoactive composites; nanocapsules; coarse-grained molecular dynamics; computer simulation
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Ryzhkov, A.; Raikher, Y. Size-Dependent Properties of Magnetosensitive Polymersomes: Computer Modelling. Sensors 2019, 19, 5266.

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