Review Reports

Round 1

Reviewer 1 Report

This review entitled "Current Advances on the Important Roles of Enhancer RNAs in Molecular Pathways of Cancer" by Wang and Tang is generally well-written and informative. However as an important review for the field, it is advised that the authors should include more figures and tables for the readers, in each section. 

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

Wang et al review about “Current Advances on the Important Roles of Enhancer RNAs in 2 Molecular Pathways of Cancer” covers an interesting and relevant topic in the literature. Furthermore, the review is a good source of information on eRNAs in cancer.

 

I have some suggestions that can improve the review.

 

• I suggest the author add some sentences about the characteristic of eRNAs, for their structure (size, spiced, polyadenylated, and capped) and how they are processed.
• Line 122 remove “and” after Zhang and add the reference number.
• The sentence that starts in Line 133 confuses, clarify the sentence.
• Add refences in the following sentences, lines 132, 143, 154,1 77, 210, 215, 240,266, 288 and 350.
• In item 6 (Current eRNA data resources) it will be interesting for the reader if the author adds 1 or 2 paragraphs about pipelines or articles that describe how to identify eRNAS.   

Author Response

Please see the attachment.

Author Response File: Author Response.docx