Next Article in Journal
Transformation of Tertiary Benzyl Alcohols into the Vicinal Halo-Substituted Derivatives Using N-Halosuccinimides
Next Article in Special Issue
Anti-Inflammatory Effects of Aspalathus linearis and Cyclopia spp. Extracts in a UVB/Keratinocyte (HaCaT) Model Utilising Interleukin-1α Accumulation as Biomarker
Previous Article in Journal / Special Issue
Anti-Inflammatory Activity of Natural Products
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessReview
Molecules 2016, 21(10), 1322;

Natural and Synthetic Coumarins with Effects on Inflammation

SRSMC, UMR 7565, Groupe HeCRIN, ICPM, 1 boulevard Arago, 57070 Metz, France
Chemistry of Natural Compounds Department, National Research Centre, El-Behoos St. 33, 12622 Dokki-Cairo, Egypt
Author to whom correspondence should be addressed.
Academic Editor: Norbert Latruffe
Received: 7 July 2016 / Revised: 12 September 2016 / Accepted: 26 September 2016 / Published: 2 October 2016
(This article belongs to the Special Issue Natural Products and Inflammation)
PDF [988 KB, uploaded 2 October 2016]


In this review, we will present the different aspects of coumarins and derivatives, from natural origins or synthetically prepared, and their action on inflammation. Coumarins and also furo- and pyranocoumarins are found in many different plants. These compounds are very often investigated for antioxidant properties. Other biological properties are also possible and anti-inflammation activity is one of these. As coumarins are also available quite easily via synthesis, natural ones can be prepared this way but derivatives with special substituents are also feasible. A review on the same topic appeared in 2004 and our contribution will take into account everything published since then. View Full-Text
Keywords: coumarins; furocoumarins; pyranocoumarins; inflammation coumarins; furocoumarins; pyranocoumarins; inflammation

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Kirsch, G.; Abdelwahab, A.B.; Chaimbault, P. Natural and Synthetic Coumarins with Effects on Inflammation. Molecules 2016, 21, 1322.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top