Next Issue
Volume 11, June
Previous Issue
Volume 11, April
 
 
molecules-logo

Journal Browser

Journal Browser

Molecules, Volume 11, Issue 5 (May 2006) – 10 articles , Pages 309-382

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Order results
Result details
Section
Select all
Export citation of selected articles as:
46 KiB  
Article
Synthesis of New 4(3H)-Quinazolinone Derivatives Using 5(4H)-Oxazolones
by Hooshang Hamidian, Ahmad Momeni Tikdari and Hojatollah Khabazzadeh
Molecules 2006, 11(5), 377-382; https://doi.org/10.3390/11050377 - 27 May 2006
Cited by 7 | Viewed by 7486
Abstract
New derivatives of 5(4H)-quinazolinone containing 2-imidazolin-5-one rings have been prepared from 5(4H)-oxazolone derivatives. Full article
Show Figures

Scheme 1

101 KiB  
Article
Experimental and Theoretical Study of Lanthanide Complexes Based on Linear and Macrocyclic Polyaminopolycarboxylic Acids Containing Pyrazolylethyl Arms
by Elena Pérez-Mayoral, Elena Soriano, Sebastián Cerdán and Paloma Ballesteros
Molecules 2006, 11(5), 345-356; https://doi.org/10.3390/11050345 - 17 May 2006
Cited by 7 | Viewed by 9833
Abstract
We report the synthesis of two novel Gd(III)-complexes derived from linear and macrocyclic polyaminopolycarboxylic acids 1 and 2, which contain a 3,5- dimethylpyrazolyl-ethyl arm, and a study of their relaxivity properties. The relationships between the experimental and theoretical results have provided interesting information [...] Read more.
We report the synthesis of two novel Gd(III)-complexes derived from linear and macrocyclic polyaminopolycarboxylic acids 1 and 2, which contain a 3,5- dimethylpyrazolyl-ethyl arm, and a study of their relaxivity properties. The relationships between the experimental and theoretical results have provided interesting information about the kinetic and thermodynamic stability of these complexes. Full article
Show Figures

Figure 1

58 KiB  
Communication
First Synthesis of 3-Acetyl-2-aminothiophenes Using the Gewald Reaction
by Gernot A. Eller and Wolfgang Holzer
Molecules 2006, 11(5), 371-376; https://doi.org/10.3390/11050371 - 16 May 2006
Cited by 32 | Viewed by 10154
Abstract
Novel 3-acetyl-2-aminothiophenes were prepared from cyanoacetone and1,4-dithianyl-2,5-diols using a modified Gewald reaction. The syntheses of thecorresponding acetamides, as well as that of 3-acetyl-2-amino-5-nitrothiophene – aninteresting building-block for thiophene azo dyes – are reported. Detailed spectroscopicinvestigations (1H-NMR, 13C-NMR, MS, IR) of [...] Read more.
Novel 3-acetyl-2-aminothiophenes were prepared from cyanoacetone and1,4-dithianyl-2,5-diols using a modified Gewald reaction. The syntheses of thecorresponding acetamides, as well as that of 3-acetyl-2-amino-5-nitrothiophene – aninteresting building-block for thiophene azo dyes – are reported. Detailed spectroscopicinvestigations (1H-NMR, 13C-NMR, MS, IR) of the obtained compounds are presented. Full article
Show Figures

Figure 1

12 KiB  
Correction
Molecules 2002, 7, 885-895
by Derek McPhee
Molecules 2006, 11(5), 370; https://doi.org/10.3390/11050370 - 12 May 2006
Cited by 1 | Viewed by 4150
37 KiB  
Communication
Selective Enzymatic Reduction of Aldehydes
by Guido Sello, Fulvia Orsini, Silvana Bernasconi and Patrizia Di Gennaro
Molecules 2006, 11(5), 365-369; https://doi.org/10.3390/11050365 - 12 May 2006
Cited by 11 | Viewed by 8391
Abstract
Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and [...] Read more.
Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features. Full article
75 KiB  
Article
Synthesis of Novel Sterically Demanding Carbo- and Heterocyclic β-Ketoesters
by Marko D. Mihovilovic, Thomas C. M. Fischer and Peter Stanetty
Molecules 2006, 11(5), 357-364; https://doi.org/10.3390/11050357 - 10 May 2006
Viewed by 8676
Abstract
We present an easy method for the synthesis of β-ketoesters starting from variouscarbocyclic and heterocyclic carboxylic acids and esters. The β-ketoester side-chain wasintroduced by a sequence involving α-deprotonation and quenching with CO2, conversion tothe corresponding acid chloride and subsequent chain elongation [...] Read more.
We present an easy method for the synthesis of β-ketoesters starting from variouscarbocyclic and heterocyclic carboxylic acids and esters. The β-ketoester side-chain wasintroduced by a sequence involving α-deprotonation and quenching with CO2, conversion tothe corresponding acid chloride and subsequent chain elongation using deprotonated ethylacetate. Full article
Show Figures

Figure 1

129 KiB  
Article
An Improved NMR Study of Liposomes Using 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as Model
by Oscar Cruciani, Luisa Mannina, Anatoli P. Sobolev, Cesare Cametti and AnnaLaura Segre
Molecules 2006, 11(5), 334-344; https://doi.org/10.3390/11050334 - 10 May 2006
Cited by 28 | Viewed by 12831
Abstract
In this paper we report a comparative characterization of Small UnilamellarVesicles (SUVs), Large Unilamellar Vesicles (LUVs) and Multilamellar Vesicles (MLVs)prepared from 1-palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine (POPC), carried outusing two NMR techniques, namely High Resolution NMR in solution and HighResolution–Magic Angle Spinning (HR-MAS). The size and size [...] Read more.
In this paper we report a comparative characterization of Small UnilamellarVesicles (SUVs), Large Unilamellar Vesicles (LUVs) and Multilamellar Vesicles (MLVs)prepared from 1-palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine (POPC), carried outusing two NMR techniques, namely High Resolution NMR in solution and HighResolution–Magic Angle Spinning (HR-MAS). The size and size distributions of thesevesicles were investigated using the dynamic light scattering technique. An improvedassignment of the 1H-NMR spectrum of MLVs is also reported. Full article
Show Figures

Figure 1

67 KiB  
Article
Synthesis and Antitumor Evaluation of Novel Derivatives of 6-Amino-2-phenylbenzothiazoles
by Livio Racane, Ranko Stojkovic, Vesna Tralic-Kulenovic and Grace Karminski-Zamola
Molecules 2006, 11(5), 325-333; https://doi.org/10.3390/11050325 - 9 May 2006
Cited by 43 | Viewed by 8731
Abstract
Novel derivatives of 6-amino-2-phenylbenzothiazole bearing differentsubstituents (amino, dimethylamino or fluoro) on the phenyl ring were prepared as thecorresponding hydrochloride salts. 6-Nitro-2-(substituted-phenyl)benzothiazoles (1-6) weresynthesized by condensation reactions of substituted benzaldehydes with 2-amino-5-nitrothiophenol. Nitro derivatives were reduced to the amino derivatives with SnCl2/HCl.Water [...] Read more.
Novel derivatives of 6-amino-2-phenylbenzothiazole bearing differentsubstituents (amino, dimethylamino or fluoro) on the phenyl ring were prepared as thecorresponding hydrochloride salts. 6-Nitro-2-(substituted-phenyl)benzothiazoles (1-6) weresynthesized by condensation reactions of substituted benzaldehydes with 2-amino-5-nitrothiophenol. Nitro derivatives were reduced to the amino derivatives with SnCl2/HCl.Water soluble hydrochloride salts of 6-amino-2-(substituted-phenyl)benzothiazole (13-19)were prepared using concentrated or gaseous HCl. Compounds 13-19 were found to exertcytostatic activities against malignant human cell lines: cervical (HeLa), breast (MCF-7),colon (CaCo-2), laryngeal carcinoma (Hep-2), and normal human fibroblast cell lines (WI-38). Full article
Show Figures

Figure 1

48 KiB  
Article
A Handy and Solventless Direct Route to Primary 3-[3-Aryl)-1,2,4-oxadiazol-5-yl]propionamides Using Microwave Irradiation
by Ricardo A.W. Neves, Filho and Rajendra M. Srivastava
Molecules 2006, 11(5), 318-324; https://doi.org/10.3390/11050318 - 9 May 2006
Cited by 24 | Viewed by 7786
Abstract
A one-step, simple and straightforward synthesis of the title amides from the corresponding carboxylic acids, urea and imidazole under microwave irradiation is described. Full article
Show Figures

Figure 1

142 KiB  
Article
Solvent Effects in Electrocoagulation of Selected Plant Pigments and Tannin
by Neeranuch Chairungsi, Kanlaya Jumpatong, Weerachai Phutdhawong and Duang Buddhasukh
Molecules 2006, 11(5), 309-317; https://doi.org/10.3390/11050309 - 29 Apr 2006
Cited by 6 | Viewed by 9651
Abstract
Electrocoagulation of a plant extract and certain substances representative of selected classes of plant pigments, viz. chlorophyll, a carotenoid, a phenolic substance and a tannin, was performed in ethanol containing varying amounts of water (15-75%). The results showed that the extent and efficiency [...] Read more.
Electrocoagulation of a plant extract and certain substances representative of selected classes of plant pigments, viz. chlorophyll, a carotenoid, a phenolic substance and a tannin, was performed in ethanol containing varying amounts of water (15-75%). The results showed that the extent and efficiency of coagulation of these substances tends to vary in a manner directly related to the water content of the solvent, although the tannin and the phenolic substance were less sensitive to the solvent composition and are equally well coagulated in all solvent systems studied. The findings can be applied to the removal of these substances from aqueous alcoholic plant extracts using the electrocoagulation technique. Full article
Show Figures

Figure 1

Previous Issue
Next Issue
Back to TopTop