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Article

A Comparison of Bispectral Index and Entropy During Sevoflurane Anesthesia Induction in Children with and without Diplegic Cerebral Palsy

Department of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Seoul 08308, Korea
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Author to whom correspondence should be addressed.
Entropy 2019, 21(5), 498; https://doi.org/10.3390/e21050498
Received: 29 March 2019 / Revised: 14 May 2019 / Accepted: 14 May 2019 / Published: 15 May 2019
Background: This study compared the correlation of bispectral index (BIS) or entropy with different sevoflurane concentrations between children with and without cerebral palsy (CP) during induction. Methods: For eighty-two children (40 CP and 42 non-CP children), anesthesia was induced with sevoflurane. BIS and entropy (response entropy and state entropy (RE and SE)) were recorded before and after the induction of anesthesia at end-tidal sevoflurane concentrations of 1–3 vol%. The sedation status was assessed using an Observer’s Assessment of Alertness/Sedation scale. The ability to predict awareness was estimated using the area under the receiver-operator characteristic curve (AUC) analysis. Results: RE, SE and BIS values decreased continuously over the observed concentration range of sevoflurane in both groups. The SE values while awake and the RE, SE, BIS values at 3 vol% sevoflurane were lower in children with CP than in those without CP. The AUC of the BIS was significantly better than RE or SE in children without CP. The AUC of the BIS was not significantly higher than that of the RE or SE in children with CP. Conclusion: BIS seems better correlated than entropy with the clinical state of loss of response in children without CP, but not in those with CP. View Full-Text
Keywords: cerebral palsy; consciousness monitors; electroencephalography; sevoflurane cerebral palsy; consciousness monitors; electroencephalography; sevoflurane
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MDPI and ACS Style

Kim, Y.S.; Won, Y.J.; Jeong, H.; Lim, B.G.; Kong, M.H.; Lee, I.O. A Comparison of Bispectral Index and Entropy During Sevoflurane Anesthesia Induction in Children with and without Diplegic Cerebral Palsy. Entropy 2019, 21, 498. https://doi.org/10.3390/e21050498

AMA Style

Kim YS, Won YJ, Jeong H, Lim BG, Kong MH, Lee IO. A Comparison of Bispectral Index and Entropy During Sevoflurane Anesthesia Induction in Children with and without Diplegic Cerebral Palsy. Entropy. 2019; 21(5):498. https://doi.org/10.3390/e21050498

Chicago/Turabian Style

Kim, Young S., Young J. Won, Hyerim Jeong, Byung G. Lim, Myoung H. Kong, and Il O. Lee 2019. "A Comparison of Bispectral Index and Entropy During Sevoflurane Anesthesia Induction in Children with and without Diplegic Cerebral Palsy" Entropy 21, no. 5: 498. https://doi.org/10.3390/e21050498

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