Special Issue "Pancreatic Cancer"

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A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: closed (30 November 2010)

Special Issue Editor

Guest Editor
Dr. Christian Pilarsky
Klinik und Poliklinik für Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstraße 74, 01307 Dresden, Germany
Website: http://www.uniklinikum-dresden.de/das-klinikum/kliniken-polikliniken-institute/vtg/forschung/pankreasforschung/pd-dr-christian-pilarsky
E-Mail: christian.pilarsky@uniklinikum-dresden.de
Phone: +49 351 458 166 07
Fax: +49 351 449 210 303
Interests: pancreas cancer; apoptosis; microarrays; signal transduction networks; tumor stroma interaction; prostate cancer; biomarker

Special Issue Information

Dear Colleagues,

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies in industrialized countries. It is characterized by early metastasis and aggressive, infiltrative growth along the endothelium basement membrane and neurons. However, in recent years the crucial genetic changes leading to pancreatic cancer have been indentified. Genetic analyses of patient samples have shown that the vast majority of those cancers display mutations in KRAS and the p16 locus. Despite these advancements PDAC shows an overall five-year survival rate of only 5%. Therefore new efforts have to be made in the field of translational oncology to improve the understanding, the diagnosis and the therapy of this disease.Apart from PDAC there are other pancreatic cancer types, which differ highly in patient outcome due to their tissue origin and genetic make up. Cancers like intraductal papillary mucinous neoplasia are of growing concern to the physicians and researchers in the field. This issue will focus on the recent key findings in the field of pancreatic cancer research and therapy. It will contain different articles regarding the different types of pancreatic cancer, the latest research and new strategies to improve the therapy of this disease.

Dr. Christian Pilarsky
Guest Editor

Keywords

  • pancreas
  • cancer
  • tumor suppressor gene
  • oncogene
  • KRAs
  • p53
  • SMAD
  • gene function
  • ultrasound
  • adjuvant
  • neoadjuvant therapy
  • epithelial mesenchymal transition
  • stem cells
  • apoptosis
  • zeb1
  • chemoresistance
  • survival prediction

Published Papers (43 papers)

Cancers 2011, 3(2), 2501-2515; doi:10.3390/cancers3022501
Received: 4 February 2011; in revised form: 25 April 2011 / Accepted: 17 May 2011 / Published: 25 May 2011
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Cancers 2011, 3(2), 2286-2301; doi:10.3390/cancers3022286
Received: 17 March 2011; in revised form: 9 April 2011 / Accepted: 26 April 2011 / Published: 9 May 2011
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Cancers 2011, 3(2), 1947-1956; doi:10.3390/cancers3021947
Received: 1 March 2011; in revised form: 1 April 2011 / Accepted: 1 April 2011 / Published: 13 April 2011
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Cancers 2011, 3(2), 1821-1843; doi:10.3390/cancers3021821
Received: 21 December 2010; in revised form: 29 December 2010 / Accepted: 12 January 2011 / Published: 1 April 2011
Show/Hide Abstract | Cited by 1 | PDF Full-text (2769 KB) | HTML Full-text | XML Full-text
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Cancers 2011, 3(2), 1527-1549; doi:10.3390/cancers3021527
Received: 18 February 2011; in revised form: 24 February 2011 / Accepted: 16 March 2011 / Published: 24 March 2011
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Cancers 2011, 3(2), 1513-1526; doi:10.3390/cancers3021513
Received: 5 February 2011; in revised form: 28 February 2011 / Accepted: 11 March 2011 / Published: 24 March 2011
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Cancers 2011, 3(1), 1253-1273; doi:10.3390/cancers3011253
Received: 10 February 2011; in revised form: 19 February 2011 / Accepted: 10 March 2011 / Published: 10 March 2011
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Cancers 2011, 3(1), 897-912; doi:10.3390/cancers3010897
Received: 13 January 2011; in revised form: 1 February 2011 / Accepted: 14 February 2011 / Published: 25 February 2011
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Cancers 2011, 3(1), 872-882; doi:10.3390/cancers3010872
Received: 18 January 2011; in revised form: 5 February 2011 / Accepted: 22 February 2011 / Published: 24 February 2011
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Cancers 2011, 3(1), 841-871; doi:10.3390/cancers3010841
Received: 26 January 2011; in revised form: 12 February 2011 / Accepted: 16 February 2011 / Published: 24 February 2011
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Cancers 2011, 3(1), 675-699; doi:10.3390/cancers3010675
Received: 3 December 2010; in revised form: 24 January 2011 / Accepted: 4 February 2011 / Published: 17 February 2011
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Cancers 2011, 3(1), 652-661; doi:10.3390/cancers3010652
Received: 31 December 2010; in revised form: 14 January 2011 / Accepted: 9 February 2011 / Published: 14 February 2011
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Cancers 2011, 3(1), 636-651; doi:10.3390/cancers3010636
Received: 20 December 2010; in revised form: 19 January 2011 / Accepted: 5 February 2011 / Published: 11 February 2011
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Cancers 2011, 3(1), 582-602; doi:10.3390/cancers3010582
Received: 1 December 2010; in revised form: 29 December 2010 / Accepted: 26 January 2011 / Published: 9 February 2011
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Cancers 2011, 3(1), 494-509; doi:10.3390/cancers3010494
Received: 1 December 2010; in revised form: 20 January 2011 / Accepted: 24 January 2011 / Published: 31 January 2011
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Cancers 2011, 3(1), 446-460; doi:10.3390/cancers3010446
Received: 17 December 2010; in revised form: 18 January 2011 / Accepted: 21 January 2011 / Published: 24 January 2011
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Cancers 2011, 3(1), 368-395; doi:10.3390/cancers3010368
Received: 1 December 2010; in revised form: 5 January 2011 / Accepted: 13 January 2011 / Published: 18 January 2011
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Cancers 2011, 3(1), 267-284; doi:10.3390/cancers3010267
Received: 5 November 2010; in revised form: 5 December 2010 / Accepted: 10 January 2011 / Published: 11 January 2011
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Cancers 2011, 3(1), 213-226; doi:10.3390/cancers3010213
Received: 7 December 2010; in revised form: 30 December 2010 / Accepted: 31 December 2010 / Published: 6 January 2011
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Cancers 2011, 3(1), 182-197; doi:10.3390/cancers3010182
Received: 1 December 2010; in revised form: 24 December 2010 / Accepted: 27 December 2010 / Published: 4 January 2011
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Cancers 2011, 3(1), 106-125; doi:10.3390/cancers3010106
Received: 1 December 2010; in revised form: 10 December 2010 / Accepted: 24 December 2010 / Published: 30 December 2010
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Cancers 2011, 3(1), 79-90; doi:10.3390/cancers3010079
Received: 23 November 2010; in revised form: 21 December 2010 / Accepted: 23 December 2010 / Published: 29 December 2010
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Cancers 2011, 3(1), 43-60; doi:10.3390/cancers3010043
Received: 1 November 2010; in revised form: 25 November 2010 / Accepted: 20 December 2010 / Published: 24 December 2010
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Cancers 2011, 3(1), 1-16; doi:10.3390/cancers3010001
Received: 11 November 2010; in revised form: 14 December 2010 / Accepted: 21 December 2010 / Published: 23 December 2010
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Cancers 2010, 2(4), 2138-2152; doi:10.3390/cancers2042138
Received: 1 November 2010; in revised form: 7 December 2010 / Accepted: 13 December 2010 / Published: 16 December 2010
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Cancers 2010, 2(4), 2084-2097; doi:10.3390/cancers2042084
Received: 24 October 2010; in revised form: 1 December 2010 / Accepted: 1 December 2010 / Published: 9 December 2010
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Cancers 2010, 2(4), 2058-2083; doi:10.3390/cancers2042058
Received: 9 November 2010; in revised form: 1 December 2010 / Accepted: 1 December 2010 / Published: 9 December 2010
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Cancers 2010, 2(4), 2044-2054; doi:10.3390/cancers2042044
Received: 22 October 2010; in revised form: 29 November 2010 / Accepted: 30 November 2010 / Published: 2 December 2010
Show/Hide Abstract | Cited by 3 | PDF Full-text (141 KB) | HTML Full-text | XML Full-text

Cancers 2010, 2(4), 2026-2043; doi:10.3390/cancers2042026
Received: 18 October 2010; in revised form: 9 November 2010 / Accepted: 22 November 2010 / Published: 29 November 2010
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Cancers 2010, 2(4), 2001-2010; doi:10.3390/cancers2042001
Received: 30 October 2010; Accepted: 17 November 2010 / Published: 25 November 2010
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Cancers 2010, 2(4), 1990-2000; doi:10.3390/cancers2041990
Received: 12 October 2010; in revised form: 11 November 2010 / Accepted: 22 November 2010 / Published: 24 November 2010
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Cancers 2010, 2(4), 1901-1910; doi:10.3390/cancers2041901
Received: 19 October 2010; in revised form: 8 November 2010 / Accepted: 16 November 2010 / Published: 18 November 2010
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Cancers 2010, 2(4), 1861-1883; doi:10.3390/cancers2041861
Received: 12 October 2010; in revised form: 3 November 2010 / Accepted: 4 November 2010 / Published: 10 November 2010
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Cancers 2010, 2(4), 1830-1837; doi:10.3390/cancers2041830
Received: 21 October 2010; Accepted: 29 October 2010 / Published: 2 November 2010
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Cancers 2010, 2(4), 1794-1812; doi:10.3390/cancers2041794
Received: 17 September 2010; in revised form: 14 October 2010 / Accepted: 18 October 2010 / Published: 25 October 2010
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Cancers 2010, 2(4), 1779-1793; doi:10.3390/cancers2041779
Received: 10 September 2010; in revised form: 8 October 2010 / Accepted: 11 October 2010 / Published: 13 October 2010
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Cancers 2010, 2(3), 1661-1682; doi:10.3390/cancers2031661
Received: 28 July 2010; in revised form: 2 September 2010 / Accepted: 2 September 2010 / Published: 9 September 2010
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Cancers 2010, 2(3), 1629-1641; doi:10.3390/cancers2031629
Received: 2 July 2010; in revised form: 29 July 2010 / Accepted: 18 August 2010 / Published: 19 August 2010
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Cancers 2010, 2(3), 1617-1628; doi:10.3390/cancers2031617
Received: 30 June 2010; in revised form: 16 August 2010 / Accepted: 17 August 2010 / Published: 18 August 2010
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Cancers 2010, 2(3), 1565-1575; doi:10.3390/cancers2031565
Received: 28 July 2010; in revised form: 5 August 2010 / Accepted: 6 August 2010 / Published: 9 August 2010
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Cancers 2010, 2(3), 1513-1527; doi:10.3390/cancers2031513
Received: 2 June 2010; in revised form: 30 June 2010 / Accepted: 7 July 2010 / Published: 14 July 2010
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Cancers 2010, 2(3), 1492-1512; doi:10.3390/cancers2031492
Received: 26 May 2010; in revised form: 28 June 2010 / Accepted: 8 July 2010 / Published: 14 July 2010
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Cancers 2010, 2(2), 1107-1124; doi:10.3390/cancers2021107
Received: 24 March 2010; in revised form: 21 May 2010 / Accepted: 24 May 2010 / Published: 2 June 2010
Show/Hide Abstract | Cited by 3 | PDF Full-text (257 KB) | HTML Full-text | XML Full-text

Last update: 25 February 2014

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