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Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries
Department of Visceral-, Thoracic- and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, Germany
These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 24 March 2010; in revised form: 21 May 2010 / Accepted: 24 May 2010 / Published: 2 June 2010
Abstract: The low prevalence of pancreatic cancer remains an obstacle to the development of effective screening tools in an asymptomatic population. However, development of effective serologic markers still offers the potential for improvement of diagnostic capabilities, especially for subpopulations of patients with high risk for pancreatic cancer. The accurate identification of patients with pancreatic cancer and the exclusion of disease in those with benign disorders remain important goals. While clinical experience largely dismissed many candidate markers as useful markers of pancreatic cancer, CA19-9 continues to show promise. The present review highlights the development and the properties of different tumor markers in pancreatic cancer and their impact on the diagnostic and treatment of this aggressive disease.
Keywords: pancreatic cancer; serum tumor markers
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Rückert, F.; Pilarsky, C.; Grützmann, R. Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries. Cancers 2010, 2, 1107-1124.
Rückert F, Pilarsky C, Grützmann R. Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries. Cancers. 2010; 2(2):1107-1124.
Rückert, Felix; Pilarsky, Christian; Grützmann, Robert. 2010. "Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries." Cancers 2, no. 2: 1107-1124.