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Cancers 2010, 2(4), 1990-2000; doi:10.3390/cancers2041990

Review

Selection and Outcome of Portal Vein Resection in Pancreatic Cancer

Akimasa Nakao

Department of Surgery II, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan

Received: 12 October 2010; in revised form: 11 November 2010 / Accepted: 22 November 2010 / Published: 24 November 2010

(This article belongs to the Special Issue Pancreatic Cancer)

Download PDF Full-Text [542 KB, uploaded 24 November 2010 14:52 CET]

Abstract: Pancreatic cancer has the worst prognosis of all gastrointestinal neoplasms. Five-year survival of pancreatic cancer after pancreatectomy is very low, and surgical resection is the only option to cure this dismal disease. The standard surgical procedure is pancreatoduodenectomy (PD) for pancreatic head cancer. The morbidity and especially the mortality of PD have been greatly reduced. Portal vein resection in pancreatic cancer surgery is one attempt to increase resectability and radicality, and the procedure has become safe to perform. Clinicohistopathological studies have shown that the most important indication for portal vein resection in patients with pancreatic cancer is the ability to obtain cancer-free surgical margins. Otherwise, portal vein resection is contraindicated.

Keywords: pancreatic cancer; portal vein resection; isolated pancreatectomy; catheter-bypass of the portal vein

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