New Advances in Physical Therapy and Occupational Therapy, 2nd Edition

Topic Information

Dear Colleagues,

This Topic is a continuation of the previous successful Topic “New Advances in Physical Therapy and Occupational Therapy” (https://www.mdpi.com/topics/2P56LO6387). Physical therapy has seen remarkable growth in recent years due to technological breakthroughs, novel therapeutic approaches, and a deeper collective understanding of biomechanics. This Topic aims to be a platform for the dissemination of pioneering research, pushing the boundaries of traditional practices and fostering dynamic idea exchange.

Our focus is on diverse therapeutic approaches, such as manual therapy, electrotherapy, exercise regimens, soft tissue mobilization, and taping methodologies. Authors are invited to explore these interventions' applications and their effects on patients with various conditions. We aim to provide practitioners with a comprehensive understanding of interventional efficacy in diverse clinical scenarios using empirical evidence and case studies.

We also seek submissions on innovative clinical measurement methods, encouraging insights into assessing patient progress, functional outcomes, and treatment efficacy using advanced technologies or interdisciplinary approaches.

Researchers worldwide are invited to contribute to topics like rehabilitation techniques, technological interventions, evidence-based practices, and interdisciplinary collaborations. Our goal is to showcase the advancements revolutionizing physical therapy and ultimately enhancing patient outcomes.

Join us on this journey to propel the field forward through collaboration and knowledge exchange. Your contributions will enrich academic discourse and directly impact global patient care. We eagerly await your submissions.

Best Regards,
Dr. Hye-Rim Suh
Dr. Suk-Chan Hahm
Dr. Hwi-Young Cho
Prof. Dr. Ki-Hun Cho
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Journal of Clinical Medicine jcm	2.9	5.2	2012	17.7 Days	CHF 2600	Submit
Journal of Personalized Medicine jpm	-	6.0	2011	21.5 Days	CHF 2600	Submit
Medicina medicina	2.4	4.1	1920	17.5 Days	CHF 2200	Submit
Healthcare healthcare	2.7	4.7	2013	21.5 Days	CHF 2700	Submit

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13 pages, 1100 KB  

Open AccessArticle

Acute Effects of Osteopathic Treatment in Long COVID-19 Patients with Fatigue Symptoms: A Randomized, Controlled Trial

by Ulrich M. Zissler, Tino Poehlmann, Rainer Gloeckl, Sami Ibrahim, Kerstin Klupsch, Tessa Schneeberger, Inga Jarosch and Andreas Rembert Koczulla

J. Clin. Med. 2025, 14(17), 6066; https://doi.org/10.3390/jcm14176066 - 27 Aug 2025

Viewed by 436

Abstract

Background: Persistent fatigue is among the most commonly reported symptoms in patients suffering from post-acute sequelae of SARS-CoV-2 infection (long COVID). Autonomic dysfunction, measurable via heart rate variability, has been implicated as a contributing factor. Osteopathic manipulative treatment is a manual therapeutic [...] Read more.

Background: Persistent fatigue is among the most commonly reported symptoms in patients suffering from post-acute sequelae of SARS-CoV-2 infection (long COVID). Autonomic dysfunction, measurable via heart rate variability, has been implicated as a contributing factor. Osteopathic manipulative treatment is a manual therapeutic approach that targets autonomic balance and may offer a novel intervention for long COVID-related fatigue. Methods: In this single-blind, randomized controlled trial, 42 participants (mean age 51 ± 11 years; fatigue severity score: 31 ± 5 points) with long COVID and persistent fatigue ≥12 weeks post-infection were allocated to either a 45 min standardized osteopathic treatment (n = 21) or a sham-treatment group (n = 21). Heart rate variability was assessed using a 10 min resting electrocardiogram before intervention, immediately after, and again 48 h later. The analysis of heart rate variability encompassed time-domain indices, including the root mean square of successive differences, the standard deviation of normal-to-normal intervals, mean heart rate, and mean RR interval. Additionally, frequency-domain measures such as low-frequency, high-frequency, total power, and the LF/HF ratio were considered. Results: The osteopathy group showed a statistically significant increase in root mean square of successive differences post-treatment (p < 0.01), accompanied by a decrease in the stress index (p < 0.05) and an increase in the mean of the standard deviations of RR intervals (p < 0.05). Significant between-group differences were observed for mean heart rate and mean of RR intervals (p < 0.05). Frequency-domain measures also improved significantly from baseline in the intervention group. Outlier patterns suggest potential subgroup effects, possibly due to underlying dysautonomia. Conclusions: A single session of osteopathic treatment significantly enhanced short-term heart rate variability in long COVID patients with fatigue. These findings highlight the potential role of manual autonomic modulation as a supportive therapy in long COVID management. Further research is needed to assess the long-term effects and optimal treatment frequency of osteopathic manipulative treatment in this population. Full article

(This article belongs to the Topic New Advances in Physical Therapy and Occupational Therapy, 2nd Edition)

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