Advances in Gene Therapy of Human Diseases

Dear colleagues,

Gene therapy has made remarkable progress in recent years, offering promising treatment options for a wide range of diseases. Innovative therapeutic developments have shown highly encouraging results in treating many conditions, including inherited disorders, neurological diseases, certain types of cancer, cardiovascular diseases, autoimmune disorders, and rare genetic conditions. Novel therapeutic interventions including gene editing, gene addition, and RNA-based therapies have opened up new avenues for more effective, targeted treatments, bringing hope to patients with previously untreatable conditions.

In this Special Issue, we aim to cover the latest advancements in therapeutic strategies for a wide range of human diseases through original research articles and expert reviews. We will highlight approaches involving gene replacement, genome modification, nucleic acid-based therapies such as antisense oligonucleotides and miRNAs, RNA interference, and innovative delivery systems like viral vectors and nanoparticles.

Prof. Dr. Leonidas A. Phylactou
Dr. Andrie Koutsoulidou
Prof. Dr. Nicola Borbone
Dr. Monica Terracciano
Topic Editors