Neonatal Infection: Antibiotics for Prevention and Treatment
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 30 November 2025 | Viewed by 56
Special Issue Editors
Interests: neonatology; neonatal medicine; neonatal sepsis; neonatal resuscitation; neonatal screening
Interests: pregnancy and viral infections
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Infections, particularly bacterial sepsis, represent a leading cause of death and healthcare resource consumption across all age groups. Despite lower mortality rates in infants and children over the past two decades, severe sepsis remains a common cause of death. Premature newborns are particularly vulnerable due to their immature immune systems and the necessity for invasive treatments. Timely antibiotic administration is critical in reducing sepsis mortality in newborns and children. However, diagnostic complexities often result in excessive antibiotic use, leading to the emergence of antibiotic-resistant microorganisms. The tracking of changes in neonatal sepsis prevention and treatment is also hindered by inconsistent definitions that make it difficult to compare data between neonatal centers and between different countries. The diagnosis of organ dysfunction in newborns and preterm infants presents significant challenges due to the absence of baseline values that reflect the temporary alterations associated with the transition from intrauterine to extrauterine life. This complexity further complicates the identification of sepsis in this population. Positive blood cultures, the gold-standard diagnosis method, only confirm infection in 9% of neonates with sepsis.
This Special Issue will address neonatal infections, including bacterial and fungal sepsis, epidemiology, definitions, severity scores, antibiotic use, biomarkers, new antibiotics, antibiotic stewardship, multi-resistance in microorganisms, and challenging infections.
Prof. Dr. Cinzia Auriti
Dr. Maria Paola Ronchetti
Guest Editors
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Keywords
- neonatal infections
- neonatal sepsis
- sepsis definition
- antibiotics in newborns
- antibiotic stewardship
- sepsis biomarkers
- sepsis diagnosis in newborns
- epidemiology of neonatal infections
- fungal invasive infections
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