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Search Results (347)

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18 pages, 4521 KB  
Article
An Adaptive Variable-Parameter MAF-MATCH Algorithm for Grid-Voltage Detection Under Non-Ideal Conditions
by Xielin Shen, Yanqiang Lin, Bo Yuan, Dongdong Chen and Zhenyu Li
Electronics 2025, 14(21), 4288; https://doi.org/10.3390/electronics14214288 (registering DOI) - 31 Oct 2025
Abstract
With the increasing penetration of renewable energy and the rising demand for power quality, the dynamic performance and accuracy of grid-voltage detection have become crucial for the control of grid-following devices such as dynamic voltage restorers (DVRs). However, the conventional moving average filter [...] Read more.
With the increasing penetration of renewable energy and the rising demand for power quality, the dynamic performance and accuracy of grid-voltage detection have become crucial for the control of grid-following devices such as dynamic voltage restorers (DVRs). However, the conventional moving average filter (MAF) in grid-voltage detection suffers from inherent limitations in dynamic response. To address this issue, this paper proposes a voltage-detection method, which is based on an adaptive variable-parameter filtering algorithm termed MAF-MATCH-V. First, a cascaded filter model is constructed by integrating a zero-pole matcher (MATCH) with the MAF. Frequency-domain analysis demonstrates that the MATCH compensates for the mid- and high-frequency magnitude attenuation and reduces the phase delay of the MAF, thereby accelerating the dynamic response while preserving its harmonic-rejection capability. Second, the influence of the matching coefficient on the time-domain response is investigated, and a time-varying adaptive strategy is designed to balance rapid disturbance recognition with steady-state convergence. Finally, experimental results under various non-ideal grid conditions demonstrate that the proposed method achieves superior overall performance compared with conventional approaches. Specifically, MAF-MATCH-V realizes millisecond-level event recognition and zero steady-state error convergence, making it a practical solution for the real-time control of grid-following equipment in modern power systems. Full article
(This article belongs to the Section Power Electronics)
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12 pages, 2632 KB  
Article
Reconfigurable Dual-Band SIW Bandpass Filter with Tunable Passbands and Enhanced Stopband Suppression
by Yongchae Jeong and Phanam Pech
Micromachines 2025, 16(11), 1206; https://doi.org/10.3390/mi16111206 - 23 Oct 2025
Viewed by 472
Abstract
This paper presents a design approach for a dual-band substrate-integrated waveguide (SIW) bandpass filter (BPF) featuring passband tunability and wide-stopband characteristics. The proposed circuit is realized using half-mode (HM) SIW cavities loaded with tunable stopband resonators (TSRs). The TSRs are realized using transmission [...] Read more.
This paper presents a design approach for a dual-band substrate-integrated waveguide (SIW) bandpass filter (BPF) featuring passband tunability and wide-stopband characteristics. The proposed circuit is realized using half-mode (HM) SIW cavities loaded with tunable stopband resonators (TSRs). The TSRs are realized using transmission lines and varactor diodes. Passband tunability can be achieved by adjusting the supply voltage on the varactor diode. Wide-stopband characteristics can be achieved by integrating the defected microstrip structure into the proposed circuit. To validate the proposed concept, dual-band HM SIW BPFs with fixed and tunable passbands has been designed and fabricated. Based on the measurement results, the proposed circuits demonstrate high-frequency selectivity, with an attenuation level better than 20 dB and measured up to more than 40 GHz at the highest stopband. Moreover, the proposed tunable dual-band HM SIW BPF provides a passband tuning range of 240 MHz, measured from 4.88 GHz to 5.12 GHz for the first passband, and 310 MHz, measured from 6.19 GHz to 6.5 GHz for the second passband. Within the passband tuning range, the insertion loss varied from 1.7 dB to 2.2 dB for the first passband and 2.1 dB to 2.5 dB for the second passband. Full article
(This article belongs to the Special Issue RF Devices: Technology and Progress)
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19 pages, 3339 KB  
Article
Sensorless Control of Permanent Magnet Synchronous Motor in Low-Speed Range Based on Improved ESO Phase-Locked Loop
by Minghao Lv, Bo Wang, Xia Zhang and Pengwei Li
Processes 2025, 13(10), 3366; https://doi.org/10.3390/pr13103366 - 21 Oct 2025
Viewed by 384
Abstract
Aiming at the speed chattering problem caused by high-frequency square wave injection in permanent magnet synchronous motors (PMSMs) during low-speed operation (200–500 r/min), this study intends to improve the rotor position estimation accuracy of sensorless control systems as well as the system’s ability [...] Read more.
Aiming at the speed chattering problem caused by high-frequency square wave injection in permanent magnet synchronous motors (PMSMs) during low-speed operation (200–500 r/min), this study intends to improve the rotor position estimation accuracy of sensorless control systems as well as the system’s ability to resist harmonic interference and sudden load changes. The goal is to enhance the control performance of traditional control schemes in this scenario and meet the requirement of stable low-speed operation of the motor. First, the study analyzes the harmonic error propagation mechanism of high-frequency square wave injection and finds that the traditional PI phase-locked loop (PI-PLL) is susceptible to high-order harmonic interference during demodulation, which in turn leads to position estimation errors and periodic speed fluctuations. Therefore, the extended state observer phase-locked loop (ESO-PLL) is adopted to replace the traditional PI-PLL. A third-order extended state observer (ESO) is used to uniformly regard the system’s unmodeled dynamics, external load disturbances, and harmonic interference as “total disturbances”, realizing real-time estimation and compensation of disturbances, and quickly suppressing the impacts of harmonic errors and sudden load changes. Meanwhile, a dynamic pole placement strategy for the speed loop is designed to adaptively adjust the controller’s damping ratio and bandwidth parameters according to the motor’s operating states (loaded/unloaded, steady-state/transient): large poles are used in the start-up phase to accelerate response, small poles are switched in the steady-state phase to reduce errors, and a smooth attenuation function is used in the transition phase to achieve stable parameter transition, balancing the system’s dynamic response and steady-state accuracy. In addition, high-frequency square wave voltage signals are injected into the dq axes of the rotating coordinate system, and effective rotor position information is extracted by combining signal demodulation with ESO-PLL to realize decoupling of high-frequency response currents. Verification through MATLAB/Simulink simulation experiments shows that the improved strategy exhibits significant advantages in the low-speed range of 200–300 r/min: in the scenario where the speed transitions from 200 r/min to 300 r/min with sudden load changes, the position estimation curve of ESO-PLL basically overlaps with the actual curve, while the PI-PLL shows obvious deviations; in the start-up and speed switching phases, dynamic pole placement enables the motor to respond quickly without overshoot and no obvious speed fluctuations, whereas the traditional fixed-pole PI control has problems of response lag or overshoot. In conclusion, the “ESO-PLL + dynamic pole placement” cooperative control strategy proposed in this study effectively solves the problems of harmonic interference and load disturbance caused by high-frequency square wave injection in the low-speed range and significantly improves the accuracy and robustness of PMSM sensorless control. This strategy requires no additional hardware cost and achieves performance improvement only through algorithm optimization. It can be directly applied to PMSM control systems that require stable low-speed operation, providing a reliable solution for the promotion of sensorless control technology in low-speed precision fields. Full article
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19 pages, 1765 KB  
Article
Reference High-Voltage Sensing Chain for the Assessment of Class 0.1-WB3 Instrument Transformers in the Frequency Range up to 150 kHz According to IEC 61869
by Mohamed Agazar, Claudio Iodice and Mario Luiso
Sensors 2025, 25(20), 6416; https://doi.org/10.3390/s25206416 - 17 Oct 2025
Viewed by 239
Abstract
This paper presents the development and characterization of a reference high-voltage sensing chain for the calibration and conformity assessment of instrument transformers with Class 0.1-WB3, in the extended frequency range up to 150 kHz, according to IEC 61869. The sensing chain, composed of [...] Read more.
This paper presents the development and characterization of a reference high-voltage sensing chain for the calibration and conformity assessment of instrument transformers with Class 0.1-WB3, in the extended frequency range up to 150 kHz, according to IEC 61869. The sensing chain, composed of a high-voltage divider, precision attenuators and high-pass filters, has been specifically developed and characterized. The chain features two parallel measurement paths: the first path, comprising the high-voltage divider and attenuator, is optimized for measuring the fundamental frequency superimposed with high-amplitude harmonics; the second path, consisting of the high-voltage divider followed by a high-pass filter, is dedicated to measuring very-low-level superimposed harmonic components by enhancing the signal-to-noise ratio. These two paths are integrated with a digitizer to form a complete and modular measurement chain. The expanded uncertainty of measurement has been thoroughly evaluated and confirms the chain’s ability to support assessment of instrument transformers with Class 0.1-WB3 compliance. Additionally, the chain architecture enables a future extension up to 500 kHz, addressing the growing need to evaluate instrument transformers under high-frequency power quality disturbances and improving the sensing capability in this field. Full article
(This article belongs to the Section Electronic Sensors)
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33 pages, 8203 KB  
Article
Applying Entropic Measures, Spectral Analysis, and EMD to Quantify Ion Channel Recordings: New Insights into Quercetin and Calcium Activation of BK Channels
by Przemysław Borys, Paulina Trybek, Beata Dworakowska, Anna Sekrecka-Belniak, Michał Wojcik and Agata Wawrzkiewicz-Jałowiecka
Entropy 2025, 27(10), 1047; https://doi.org/10.3390/e27101047 - 9 Oct 2025
Viewed by 392
Abstract
Understanding the functional modulation of ion channels by multiple activating substances is critical to grasping stimulus-specific gating mechanisms and possible synergistic or competitive interactions. This study investigates the activation of large-conductance, voltage- and Ca2+-activated potassium channels (BK) in the plasma membrane [...] Read more.
Understanding the functional modulation of ion channels by multiple activating substances is critical to grasping stimulus-specific gating mechanisms and possible synergistic or competitive interactions. This study investigates the activation of large-conductance, voltage- and Ca2+-activated potassium channels (BK) in the plasma membrane of human bronchial epithelial cells by Ca2+ and quercetin (Que), both individually and in combination. Patch-clamp recordings were analyzed using open state probability, dwell-time distributions, Shannon entropy, sample entropy, power spectral density (PSD), and empirical mode decomposition (EMD). Our results reveal concentration-dependent alterations in gating kinetics, particularly at a low concentration of quercetin ([Que] = 10 μM) compared with [Que] = 100 μM, where some Que-related effects are strongly attenuated in the presence of Ca2+. We also identify specific frequency bands where oscillatory components are most sensitive to the considered stimuli. Our findings highlight the complex reciprocal interplay between Ca2+ and Que in modulating BK channel function, and demonstrate the interpretative power of entropic and signal-decomposition approaches in characterizing stimulus-specific gating dynamics. Full article
(This article belongs to the Special Issue Mathematical Modeling for Ion Channels)
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14 pages, 2439 KB  
Article
A Traceable Low-Frequency Attenuation Standard from 1 kHz to 10 MHz for Next-Generation Wireless and EMC Calibration
by Anton Widarta
Sensors 2025, 25(19), 6227; https://doi.org/10.3390/s25196227 - 8 Oct 2025
Viewed by 438
Abstract
The growing demand for traceable, high-precision attenuation measurements in electromagnetic compatibility (EMC) testing and low-frequency wireless communication systems has driven the development of a primary attenuation standard covering 1 kHz to 10 MHz. The system employs a dual channel null-detection method using an [...] Read more.
The growing demand for traceable, high-precision attenuation measurements in electromagnetic compatibility (EMC) testing and low-frequency wireless communication systems has driven the development of a primary attenuation standard covering 1 kHz to 10 MHz. The system employs a dual channel null-detection method using an inductive voltage divider (IVD) as a reference, ensuring the highest accuracy and traceability while eliminating sensitivity to detector nonlinearity. Attenuation at 1 kHz, 9 kHz, and 10 kHz is measured directly against the IVD ratio, while higher-frequency measurements (100 kHz–10 MHz) are performed via heterodyne detection, down-converting signals to 1 kHz for comparison. To ensure comparable accuracy at higher attenuation levels, a double-step method is applied at 9 kHz and 10 kHz to mitigate the increased IVD uncertainty above 1 kHz. Linearity is ensured by suppressing common-mode currents with toroidal ferrite chokes and minimizing inter-channel coupling. Type B (non-statistical) measurement uncertainties are evaluated, with major contributions from the IVD reference, system errors, and mismatch. The expanded uncertainties are 2.2 × 10−3 dB at 20 dB, 3.0 × 10−3 dB at 40 dB, and 4.0 × 10−3 dB at 60 dB attenuation. To facilitate wider dissemination and extend the calibration range, a resistive step attenuator with 10 dB pads is evaluated as a practical transfer standard, providing a simple and robust solution for traceable attenuation calibration in this frequency range. Full article
(This article belongs to the Special Issue Novel Signal Processing Techniques for Wireless Communications)
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15 pages, 6150 KB  
Article
Second-Order Complex-Coefficient Flux Observer with Stator Resistance Estimation for Induction Motor Sensorless Drives
by Kun Zhao, Bao Song, Xiaoqi Tang and Xiangdong Zhou
Machines 2025, 13(9), 845; https://doi.org/10.3390/machines13090845 - 11 Sep 2025
Viewed by 420
Abstract
The voltage model (VM) is widely used in sensorless induction motor drives owing to its structural simplicity and speed-independence. However, DC offsets in back electromotive force (BEMF) caused by measurement errors can degrade the accuracy of flux and speed estimation. To address this [...] Read more.
The voltage model (VM) is widely used in sensorless induction motor drives owing to its structural simplicity and speed-independence. However, DC offsets in back electromotive force (BEMF) caused by measurement errors can degrade the accuracy of flux and speed estimation. To address this issue, this article proposes a second-order complex-coefficient flux observer (SCFO) that effectively eliminates DC offsets without introducing phase delay and amplitude attenuation, while maintaining excellent dynamic performance. Furthermore, to enhance the robustness of the flux observer against stator resistance variations, an improved stator resistance adaptive law based on the rotating reference frame is proposed. Ultimately, experimental validation on a 1.5 kW induction motor drive platform confirms the effectiveness of the proposed sensorless scheme. Full article
(This article belongs to the Section Electrical Machines and Drives)
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17 pages, 5272 KB  
Article
Enhanced Clustering of DC Partial Discharge Pulses Using Multi-Level Wavelet Decomposition and Principal Component Analysis
by Sung-Ho Yoon, Ik-Su Kwon, Jin-Seok Lim, Byung-Bae Park, Seung-Won Lee and Hae-Jong Kim
Energies 2025, 18(18), 4835; https://doi.org/10.3390/en18184835 - 11 Sep 2025
Viewed by 407
Abstract
Partial discharge (PD) is a critical indicator of insulation degradation in high-voltage DC systems, necessitating accurate diagnosis to ensure long-term reliability. Conventional AC-based diagnostic methods, such as phase-resolved partial discharge analysis (PRPDA), are ineffective under DC conditions, emphasizing the need for waveform-based analysis. [...] Read more.
Partial discharge (PD) is a critical indicator of insulation degradation in high-voltage DC systems, necessitating accurate diagnosis to ensure long-term reliability. Conventional AC-based diagnostic methods, such as phase-resolved partial discharge analysis (PRPDA), are ineffective under DC conditions, emphasizing the need for waveform-based analysis. This study presents a novel clustering framework for DC PD pulses, leveraging multi-level wavelet decomposition and statistical feature extraction. Each signal is decomposed into multiple frequency bands, and 70 distinctive waveform features are extracted from each pulse. To mitigate feature redundancy and enhance clustering performance, principal component analysis (PCA) is employed for dimensionality reduction. Experimental data were obtained from multiple defect types and measurement distances using a 22.9 kV cross-linked polyethylene (XLPE) cable system. The proposed method significantly outperformed conventional time-frequency (T-F) mapping techniques, particularly in scenarios involving signal attenuation and mixed noise. Propagation-induced distortion was effectively addressed through multi-resolution analysis. In addition, field noise sources such as HVDC converter switching transients and fluorescent lamp emissions were included to assess robustness. The results confirmed the framework’s capability to distinguish between multiple PD types and noise sources, even in challenging environments. Furthermore, optimal mother wavelet selection and correlation-based feature analysis contributed to improved clustering resolution. This framework supports robust PD classification in practical HVDC diagnostics. The framework can contribute to the development of real-time autonomous monitoring systems for HVDC infrastructure. Future research will explore incorporating temporal deep learning architectures for automated PD-type recognition based on clustered data. Full article
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26 pages, 3027 KB  
Article
Cinnarizine, a Calcium Channel Blocker, Partially Prevents the Striatal Dopamine Decline and Loss of Nigral Dopamine Neurons in the Lactacystin-Induced Rat Model of Parkinson’s Disease
by Elżbieta Lorenc-Koci, Tomasz Lenda, Jolanta Konieczny, Danuta Jantas and Helena Domin
Int. J. Mol. Sci. 2025, 26(18), 8833; https://doi.org/10.3390/ijms26188833 - 10 Sep 2025
Viewed by 691
Abstract
Selective proteasome inhibitors, used to model Parkinsonian-like pathology, are known to disrupt calcium homeostasis, but the role of calcium ions in dopaminergic neuron degeneration remains unclear. The present in vivo study examined the effects of a 7-day intraperitoneal administration of cinnarizine (10 or [...] Read more.
Selective proteasome inhibitors, used to model Parkinsonian-like pathology, are known to disrupt calcium homeostasis, but the role of calcium ions in dopaminergic neuron degeneration remains unclear. The present in vivo study examined the effects of a 7-day intraperitoneal administration of cinnarizine (10 or 30 mg/kg), a voltage-gated calcium channel blocker, in rats unilaterally injected into the substantia nigra compacta (SNc) with lactacystin (Lac; 1 µg/2 µL) or vehicle. Dopamine (DA) and its metabolites were quantified in striatal homogenates via high-performance liquid chromatography. The SN of rats treated with 10 mg/kg cinnarizine was used for Western blot analysis of tyrosine hydroxylase (TH), while tissue from animals receiving 30 mg/kg was processed for histological analysis of TH-immunoreactive (TH-ir) and cresyl violet (CV)-stained neurons. Significant reductions in striatal DA and its metabolites were observed one week after Lac injection, along with increased DA catabolism. Cinnarizine at both doses partially prevented DA loss and attenuated enhanced DA turnover. Moreover, 10 mg/kg cinnarizine partially preserved TH protein levels, while 30 mg/kg provided histological protection of TH-ir neurons in the SN. Cinnarizine was also tested in vitro in human SH-SY5Y neuroblastoma cells and primary mouse cortical neurons exposed to Lac or rotenone to further assess its neuroprotective potential. In SH-SY5Y cells, cinnarizine (1–10 µM) significantly increased cell viability and reduced lactate dehydrogenase release after toxin exposure. Cinnarizine failed to counteract lactacystin-induced toxicity in primary cortical neurons but markedly reduced rotenone-evoked cell death at similar concentrations. These findings indicate that cinnarizine exerts dose-dependent neuroprotective effects in vivo and selective protective actions in vitro, supporting the potential utility of voltage-gated calcium channel blockers in treating Parkinson’s disease. Full article
(This article belongs to the Special Issue Neuroprotective Effects of Food Ingredients)
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12 pages, 1983 KB  
Article
Non-Destructive Evaluation of HTV’s Thermal-Oxidative Aging Using Terahertz Dielectric Spectroscopy
by Tengyi Zhang, Li Cheng, Shuo Zhang, Bo Tao and Yipu Tang
Materials 2025, 18(17), 4176; https://doi.org/10.3390/ma18174176 - 5 Sep 2025
Viewed by 791
Abstract
Thermal oxidative aging failure of high-temperature vulcanized silicone rubber (HTV) in high-voltage insulators is the core hidden danger of power grid security. In this study, terahertz time domain spectroscopy (THz-TDS) and attenuated total reflection infrared spectroscopy (ATR-FTIR) were combined to reveal the quantitative [...] Read more.
Thermal oxidative aging failure of high-temperature vulcanized silicone rubber (HTV) in high-voltage insulators is the core hidden danger of power grid security. In this study, terahertz time domain spectroscopy (THz-TDS) and attenuated total reflection infrared spectroscopy (ATR-FTIR) were combined to reveal the quantitative structure–activity relationship between dielectric response and chemical group evolution of HTV during accelerated aging at 200 °C for 80 days. In this study, HTV flat samples were made in the laboratory, and the dielectric spectrum of HTV in the range of 0.1 THz to 0.4 THz was extracted by a terahertz time–domain spectrum platform. ATR-FTIR was used to analyze the functional group change trend of HTV during aging, and the three-stage evolution of the dielectric real part (0.16 THz), the dynamics of the carbonyl group, the monotonic rise of the dielectric imaginary part (0.17 THz), and the linear response of silicon-oxygen bond breaking were obtained by combining the double Debye relaxation theory. Finally, three aging stages of HTV were characterized by dielectric loss angle data. The model can warn about the critical point of early oxidation and main chain fracture and identify the risk of insulation failure in advance compared with traditional methods. This study provides a multi-scale physical basis for nondestructive life assessment in a silicon rubber insulator. Full article
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27 pages, 7814 KB  
Article
Optimal Placement of Wireless Smart Concentrators in Power Distribution Networks Using a Metaheuristic Approach
by Cristoercio André Silva, Richard Wilcamango-Salas, Joel D. Melo, Jesús M. López-Lezama and Nicolás Muñoz-Galeano
Energies 2025, 18(17), 4604; https://doi.org/10.3390/en18174604 - 30 Aug 2025
Viewed by 605
Abstract
The optimal allocation of Wireless Smart Concentrators (WSCs) in low-voltage (LV) distribution networks poses significant challenges due to signal attenuation caused by varying building densities and vegetation. This paper proposes a Variable Neighborhood Search (VNS) algorithm to optimize the placement of WSCs in [...] Read more.
The optimal allocation of Wireless Smart Concentrators (WSCs) in low-voltage (LV) distribution networks poses significant challenges due to signal attenuation caused by varying building densities and vegetation. This paper proposes a Variable Neighborhood Search (VNS) algorithm to optimize the placement of WSCs in LV distribution networks. To comprehensively assess the proposed approach, both linear and nonlinear mathematical formulations are considered, depending on whether the distance between meters and concentrators is treated as a fixed parameter or as a decision variable. The performance of the proposed VNS algorithm is benchmarked against both exact solvers and metaheuristics such as Particle Swarm Optimization (PSO), Genetic Algorithm (GA), and Tabu Search (TS). In the linear formulation, VNS achieved the exact optimal solution with execution times up to 75% faster than competing methods. For the more complex nonlinear model, VNS consistently identified superior solutions while requiring less computational effort. These results underscore the algorithm’s ability to balance solution quality and efficiency, making it particularly well-suited for large-scale, resource-constrained utility planning. Full article
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14 pages, 1557 KB  
Article
Modulating CT Attenuation of Polyvinyl Alcohol Cryogels for Individualized Training Phantoms in Interventional Radiology: A Proof-of-Concept Study
by Martin Volk, Ivan Vogt, Marilena Georgiades, Johanna Menhorn, Mathias Becker, Georg Rose, Maciej Pech and Oliver S. Grosser
Gels 2025, 11(8), 664; https://doi.org/10.3390/gels11080664 - 20 Aug 2025
Viewed by 620
Abstract
Anthropomorphic CT phantoms are essential training tools for interventional radiology. Given the high technical demands and stringent safety requirements in this field, realistic CT phantoms are vital simulation tools that support effective hands-on training, procedural planning, and risk mitigation. However, commercially available phantom [...] Read more.
Anthropomorphic CT phantoms are essential training tools for interventional radiology. Given the high technical demands and stringent safety requirements in this field, realistic CT phantoms are vital simulation tools that support effective hands-on training, procedural planning, and risk mitigation. However, commercially available phantom geometries are limited in their scope. This study investigates the use of polyvinyl alcohol (PVA) to fabricate customizable training phantoms. PVA, a non-toxic material, can be processed into PVA cryogels (PVA-C) with tissue-like mechanical properties. We modified PVA-C (10 wt.% PVA) by incorporating various additives to adjust X-ray attenuation and achieve Hounsfield units (HUs) similar to different soft tissues. HU values were measured at X-ray tube voltages of 70, 120, and 150 kV. The inclusion of barium sulfate (e.g., U = 120 kV; 0.1–2 wt.%: 33.29 ± 5.45–323.72 ± 12.64 HU) and iohexol (e.g., U = 120 kV; 0.1–2 wt.%: 26.05 ± 4.74–161.99 ± 5.69 HU) significantly increased HU values. Iohexol produced more homogeneous HU distributions than barium sulfate and cellulose derivatives, with the latter having air gaps and inconsistencies. The tested formulations encompassed a wide range of soft tissue densities, with HU values varying significantly across the energy range (p < 0.001). While cellulose derivatives showed variable HU modulation, their primary role appears to be in modifying phantom texture and morphology rather than precise attenuation control. In conclusion, PVA-C demonstrates strong potential for use in interventional radiology training phantoms. Further studies may enhance phantom realism by replicating tissue textures, for example, through the incorporation of cellulose-based substances. Full article
(This article belongs to the Special Issue Gel-Related Materials: Challenges and Opportunities (2nd Edition))
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28 pages, 5564 KB  
Article
Virtual Model Development and Control for an EV3 BallBot Robotic System
by Gerardo Escandon-Esparza and Francisco Jurado
Processes 2025, 13(8), 2616; https://doi.org/10.3390/pr13082616 - 18 Aug 2025
Viewed by 1160
Abstract
In this paper, the virtual model development and control for a BallBot Robotic System (BRS) are addressed. A virtual three-dimensional (3-D) EV3 BRS (EV3BRS) model is here developed through the Simscape Multibody environment from a BRS designed using the kit LEGO [...] Read more.
In this paper, the virtual model development and control for a BallBot Robotic System (BRS) are addressed. A virtual three-dimensional (3-D) EV3 BRS (EV3BRS) model is here developed through the Simscape Multibody environment from a BRS designed using the kit LEGO® MINDSTORMS® EV3. The mathematical model from the BRS is obtained through the Euler–Lagrange approach and used as the foundation to develop the EV3BRS Simscape model. The electrical model for the motors is derived through Kirchhoff’s laws. To verify the dynamics of the EV3BRS Simscape model, a Takagi–Sugeno Fuzzy Controller (TSFC) is designed using the Parallel Distributed Compensation (PDC) technique. Control gains are computed via Linear Matrix Inequalities (LMIs). To test the EV3BRS Simscape model under disturbances, an input voltage anomaly is considered. So, adding an H attenuation to the TSFC ensures that the EV3BRS Simscape model faces these kind of anomalies. Simulation results confirm that the TSFC with H attenuation improves the performance under anomalies at the input in contrast with the nominal TSFC, although this latter can maintain the body of the system near the upright position also. The dynamics from the EV3BRS Simscape model here developed allow us to realize how the real system will behave. Full article
(This article belongs to the Special Issue Modeling and Simulation of Robot Intelligent Control System)
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22 pages, 1654 KB  
Article
Astaxanthin Attenuates Chlorpyrifos-Induced Pulmonary Cytotoxicity by Modulating Mitochondrial Redox and Inflammatory Pathways
by Mediha Demet Okudan Altındaş and Adem Güner
Curr. Issues Mol. Biol. 2025, 47(8), 663; https://doi.org/10.3390/cimb47080663 - 17 Aug 2025
Viewed by 878
Abstract
Chlorpyrifos (CPF), an organophosphate pesticide, is known to induce pulmonary toxicity through oxidative stress, mitochondrial dysfunction, and inflammation. Astaxanthin (ASX), a xanthophyll carotenoid derived primarily from marine microalgae (Haematococcus pluvialis), possesses strong antioxidant properties and has demonstrated cellular protective effects in numerous oxidative [...] Read more.
Chlorpyrifos (CPF), an organophosphate pesticide, is known to induce pulmonary toxicity through oxidative stress, mitochondrial dysfunction, and inflammation. Astaxanthin (ASX), a xanthophyll carotenoid derived primarily from marine microalgae (Haematococcus pluvialis), possesses strong antioxidant properties and has demonstrated cellular protective effects in numerous oxidative stress studies. However, its efficacy against CPF-induced lung cell damage remains uncharacterized. This study revealed the protective role of ASX, as a pretreatment and co-treatment, against CPF-induced cytotoxicity in human A549 lung adenocarcinoma cells by assessing cell viability, intracellular reactive oxygen species (IROS), total oxidative status (TOS), total antioxidant capacity (TAC), mitochondrial membrane potential (MMP), intracellular calcium ions (Ca2+), lactate dehydrogenase (LDH) release, malondialdehyde (MDA) levels, glutathione peroxidase (GPx) activity, superoxide dismutase (SOD) activity, DNA fragmentation, and apoptosis/inflammation-associated gene expression. CPF treatment significantly decreased cell viability and TAC, while elevating IROS, TOS, MMP, intracellular Ca2+, and LDH release. CPF also increased MDA levels and suppressed GPx and SOD activities. DNA fragmentation and quantitative polymerase chain reaction (qPCR) analysis revealed upregulation of pro-apoptotic and inflammatory markers such as BCL2-associated X protein (BAX), caspase-3 (CASP3), tumor protein p53 (TP53), tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), nuclear factor kappa B (NFκB), and voltage-dependent anion-selective channel protein 1 (VDAC1) and suppression of anti-apoptotic B-cell lymphoma 2 (BCL2) and antioxidant defense genes nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1). ASX treatment, particularly when administered as a pretreatment, significantly reversed CPF-induced oxidative and inflammatory responses by restoring SOD, GPx, and TAC levels, reducing IROS, TOS, MDA, and LDH release, and downregulating apoptotic and inflammatory gene expressions. ASX pretreatment notably decreased MMP and intracellular Ca2+ levels, indicating protection against mitochondrial dysfunction and calcium dysregulation. ASX upregulated Nrf2 and HO-1 expression and restored the BCL2/BAX balance, suggesting inhibition of mitochondrial-mediated apoptosis. Additionally, ASX significantly attenuated CPF-induced anti-angiogenic effects in the in ovo Hen’s Egg Test Chorioallantoic Membrane (HET-CAM) assay. These findings demonstrate, for the first time, that ASX exerts a broad spectrum of protective effects against CPF-induced cytotoxicity in lung cells, mainly through the stabilization of mitochondrial redox status and modulation of apoptosis- and inflammation-related gene pathways, highlighting ASX as a promising candidate for further therapeutic development. Furthermore, the pronounced efficacy observed in the pretreatment regimen suggests that ASX can be evaluated as a potential nutritional preventive strategy in high-risk populations with occupational or environmental CPF exposure. Full article
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23 pages, 11587 KB  
Article
Robust Sensorless Active Damping of LCL Resonance in EV Battery Grid-Tied Converters Using μ-Synthesis Control
by Nabeel Khan, Wang Cheng, Muhammad Yasir Ali Khan and Danish Khan
World Electr. Veh. J. 2025, 16(8), 422; https://doi.org/10.3390/wevj16080422 - 27 Jul 2025
Viewed by 643
Abstract
LCL (inductor–capacitor–inductor) filters are widely used in grid-connected inverters, particularly in electric vehicle (EV) battery-to-grid systems, for harmonic suppression but introduce resonance issues that compromise stability. This study presents a novel sensorless active damping strategy based on μ-synthesis control for EV batteries connected [...] Read more.
LCL (inductor–capacitor–inductor) filters are widely used in grid-connected inverters, particularly in electric vehicle (EV) battery-to-grid systems, for harmonic suppression but introduce resonance issues that compromise stability. This study presents a novel sensorless active damping strategy based on μ-synthesis control for EV batteries connected to the grid via LCL filters, eliminating the need for additional current sensors while preserving harmonic attenuation. A comprehensive state–space and process noise model enables accurate capacitor current estimation using only grid current and point-of-common-coupling (PCC) voltage measurements. The proposed method maintains robust performance under ±60% LCL parameter variations and integrates a proportional-resonant (PR) current controller for resonance suppression. Hardware-in-the-loop (HIL) validation demonstrates enhanced stability in dynamic grid conditions, with total harmonic distortion (THD) below 5% (IEEE 1547-compliant) and current tracking error < 0.06 A. Full article
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