Search Results (2,259)

Background: The rising prevalence of gastric, biliary, and pancreatic surgeries has led to an increasing population of patients with surgically altered anatomy (SAA). In this setting, conventional endoscopic retrograde cholangiopancreatography (ERCP) is often limited by anatomical barriers, resulting in high rates of technical failure and complications. While device-assisted enteroscopy (DAE) has expanded therapeutic possibilities, its efficacy remains modest in complex reconstructions. Methods: This review analyzed recent literature from PubMed, Embase, and Scopus up to April 2025, focusing on diagnostic and therapeutic roles of endoscopic ultrasound (EUS) in SAA. Particular attention was given to cases where standard endoscopic, percutaneous, or surgical techniques failed and to studies comparing EUS-guided approaches with alternative modalities. Results: EUS has transitioned from a primarily diagnostic modality to a versatile therapeutic platform in SAA. Techniques such as EUS-guided rendezvous, antegrade drainage, and hepaticogastrostomy have shown technical and clinical success rates exceeding 80–90%, often comparable or superior to interventional radiology, while reducing the need for external drains. Innovative procedures, including EUS-directed transgastric ERCP (EDGE) and EUS-directed enteroenteric bypass (EDEE), have transformed the management of Roux-en-Y gastric bypass and bilioenteric anastomoses, providing durable and reusable access for repeated interventions. Despite these advances, EUS-guided interventions remain technically demanding, requiring advanced endoscopic and radiologic skills, specialized devices, and are best performed in tertiary referral centers. Conclusions: EUS has redefined the treatment paradigm of biliopancreatic diseases in patients with SAA, increasingly emerging as the preferred minimally invasive approach when conventional techniques fail. Future developments will focus on dedicated devices, standardized guidelines, and structured training programs to optimize outcomes. Multidisciplinary collaboration and centralization in high-volume centers remain essential to ensure safety, efficacy, and reproducibility. Full article

Building Information Modeling (BIM) is a transformative tool in Sustainable Design (SD), providing measurable benefits for efficiency, collaboration, and performance in architectural, engineering, and construction (AEC) practices. Despite its growing presence in academic curricula, a gap persists between students’ recognition of BIM’s sustainability potential and their confidence or ability to apply these concepts in real-world practice. This study examines students’ understanding and perceptions of BIM and Sustainable Design education, offering insights for enhancing curriculum integration and pedagogical strategies. The objectives are to: (1) assess students’ current understanding of BIM and Sustainable Design; (2) identify gaps and misconceptions in applying BIM to sustainability; (3) evaluate the effectiveness of existing teaching methods and curricula to inform future improvements; and (4) explore the alignment between students’ theoretical knowledge and practical abilities in using BIM for Sustainable Design. The research methodology includes a comprehensive literature review and a survey of 213 students from architecture and construction management programs. Results reveal that while most students recognize the value of BIM for early-stage sustainable design analysis, many lack confidence in their practical skills, highlighting a perception–practice gap. The paper examines current educational practices, identifies curriculum shortcomings, and proposes strategies, such as integrated, hands-on learning experiences, to better align academic instruction with industry needs. Distinct from previous studies that focused primarily on single-discipline or software-based training, this research provides an empirical, cross-program analysis of students’ perception–practice gaps and offers curriculum-level insights for sustainability-driven practice. These findings provide practical recommendations for enhancing BIM and sustainability education, thereby better preparing students to meet the demands of the evolving AEC sector. Full article

A region-aware federated learning framework (RAFL) is proposed to address the non-IID heterogeneity in multi-regional crop disease recognition while reducing communication and computation costs. RAFL integrates three complementary modules: a region embedding module that captures region-specific representations, a cross-region feature alignment module that aligns semantic distributions across regions on the server, and an attention-based aggregation module that dynamically weights client updates based on performance through Transformer attention. Without sharing raw images, RAFL achieves efficient and privacy-preserving collaboration among heterogeneous farmlands. Experiments on datasets from Bayan Nur, Zhungeer, and Tangshan demonstrate substantial improvements: a classification accuracy of $89.4\%$, an F1-score of $88.5\%$, an AUC of $0.948$, while the detection performance reaches $mAP@50=62.5$. Compared with FedAvg, RAFL improves accuracy and F1 by over $5\%$, and converges faster with reduced communication overhead (total 2822 MB over 95 rounds). Ablation studies verify that the three modules act synergistically—regional embeddings enhance local discriminability, feature alignment mitigates cross-domain drift, and attention-based aggregation stabilizes training—resulting in a robust and deployable solution for large-scale, privacy-preserving agricultural monitoring. Furthermore, the framework enables regional-level economic analysis by correlating disease incidence with yield reduction and estimating potential economic losses, providing a data-driven reference for agricultural policy and resource allocation. Full article

Background: Artificial intelligence (AI), the overarching field that includes machine learning (ML) and its subfield deep learning (DL), is rapidly transforming clinical research by enabling the analysis of high-dimensional data and automating the output of diagnostic and prognostic tests. As clinical trials become increasingly complex and costly, ML-based approaches (especially DL for image and signal data) offer promising solutions, although they require new approaches in clinical education. Objective: Explore current and emerging AI applications in oncology and cardiology, highlight real-world use cases, and discuss the challenges and future directions for responsible AI adoption. Methods: This narrative review summarizes various aspects of AI technology in clinical research, exploring its promise, use cases, and its limitations. The review was based on a literature search in PubMed covering publications from 2019 to 2025. Search terms included “artificial intelligence”, “machine learning”, “deep learning”, “oncology”, “cardiology”, “digital twin”. and “AI-ECG”. Preference was given to studies presenting validated or clinically applicable AI tools, while non-English articles, conference abstracts, and gray literature were excluded. Results: AI demonstrates significant potential in improving diagnostic accuracy, facilitating biomarker discovery, and detecting disease at an early stage. In clinical trials, AI improves patient stratification, site selection, and virtual simulations via digital twins. However, there are still challenges in harmonizing data, validating models, cross-disciplinary training, ensuring fairness, explainability, as well as the robustness of gold standards to which AI models are built. Conclusions: The integration of AI in clinical research can enhance efficiency, reduce costs, and facilitate clinical research as well as lead the way towards personalized medicine. Realizing this potential requires robust validation frameworks, transparent model interpretability, and collaborative efforts among clinicians, data scientists, and regulators. Interoperable data systems and cross-disciplinary education will be critical to enabling the integration of scalable, ethical, and trustworthy AI into healthcare. Full article

Amidst global climate warming and increasingly severe food security challenges, the agroforestry economy, a green ecological industry that balances ecological conservation and economic development, has attracted widespread attention. This study constructs a theoretical analytical framework based on the diamond model to systematically identify key factors influencing the development of the agroforestry economy. Using 56 practical cases from the agroforestry economy in China as samples, the study applies Necessary Condition Analysis (NCA) and fuzzy-set Qualitative Comparative Analysis (fsQCA) to further explore the multiple driving paths of agroforestry economic development and their supporting elements. The research findings show that (1) forest resources, technological innovation, market demand, enterprise forms, related industries, and government support do not constitute necessary conditions for the development of the agroforestry economy. The path to the development of the agroforestry economy exhibits complex and concurrent multi-faceted characteristics. (2) Technological innovation has always been at the core of all configurations, and strengthening technological innovation plays a universal role in enhancing the level of agroforestry economic development. The role of government support in the process of the development of the agroforestry economy is limited. (3) The system identified four driving paths, including the endogenous type, characterized by resource technology enterprises; the collaborative type, characterized by a resource technology market with light promotion by the government; the external expansion type, characterized by market technology enterprises; and the linkage type, characterized by market technology enterprises assisted by related industries. The consistency level of the overall solution reached 0.91, and the coverage was 0.54. It reveals the different driving mechanisms with different combinations of elements for the development of the agroforestry economy. Therefore, each region should strengthen scientific and technological research, innovation, and the transformation and application of research outcomes. It should promote the coordinated development of diverse factors, establish tailored regional development models, and explore suitable pathways for developing the agroforestry economy based on its unique resource endowments. Full article

Modern engineering increasingly operates within socio-technical networks, such as the interdependence of energy grids, transport systems, and building codes, where decisions must be reliable and transparent. Large language models (LLMs) such as GPT promise efficiency by interpreting domain-specific queries and generating outputs, yet their predictive nature can introduce biases or fabricated values—risks that are unacceptable in structural engineering, where safety and compliance are paramount. This work presents a dataset that embeds generative AI into validated computational workflows through the Model Context Protocol (MCP). MCP enables API-based integration between ChatGPT (GPT-4o) and numerical solvers by converting natural-language prompts into structured solver commands. This creates context-aware exchanges—for example, transforming a query on seismic drift limits into an OpenSees analysis—whose results are benchmarked against manually generated ETABS models. This architecture ensures traceability, reproducibility, and alignment with seismic design standards. The dataset contains prompts, GPT outputs, solver-based analyses, and comparative error metrics for four reinforced concrete frame models designed under Ecuadorian (NEC-15) and U.S. (ASCE 7-22) codes. The end-to-end runtime for these scenarios, including LLM prompting, MCP orchestration, and solver execution, ranged between 6 and 12 s, demonstrating feasibility for design and verification workflows. Beyond providing records, the dataset establishes a reproducible methodology for integrating LLMs into engineering practice, with three goals: enabling independent verification, fostering collaboration across AI and civil engineering, and setting benchmarks for responsible AI use in high-stakes domains. Full article

This review explores the transformative potentials of artificial intelligence (AI) in promoting healthspan and longevity. Healthspan focuses on enhancing quality of life free from chronic conditions, while longevity defines current lifespan limits within a particular species and encompasses biological aging at multiple levels. AI methodologies—including machine learning, deep learning, natural language processing, robotics, and data analytics—offer unprecedented tools to analyze complex biological data, accelerate biomarker discovery, optimize therapeutic interventions, and personalize medicine. Notably, AI has facilitated breakthroughs in identifying accurate biomarkers of biological age, developing precision medicine approaches, accelerating drug discovery, and enhancing genomic editing technologies such as CRISPR. Further, AI-based analysis of endogenous cytoprotection, especially the activity of molecules such as heme oxygenase, with particular application to hemolytic diseases. AI-driven robotics and automated monitoring systems significantly improve elderly care, lifestyle interventions, and clinical trials, demonstrating considerable potential to extend both healthspan and lifespan. However, the integration of AI into longevity research poses ethical and societal challenges, including concerns over privacy, equitable access, and broader implications of extended human lifespans. Strategic interdisciplinary collaboration, transparent AI methodologies, standardized data frameworks, and equitable policy approaches are essential to responsibly harness AI’s full potential in transforming longevity science and improving human health. Full article

Digital transformation powered by Building Information Modeling (BIM) and Artificial Intelligence (AI) is reshaping renovation practices by addressing persistent challenges such as fragmented records, scheduling disruptions, regulatory delays, and inefficiencies in stakeholder coordination. This study explores the integration of these technologies through a case study of a Catholic church renovation (2022–2023) in Hong Kong, supplemented by insights from 10 comparable projects. The research proposes a practical framework for incorporating digital tools into renovation workflows that focuses on diagnosing challenges, defining objectives, selecting appropriate BIM/AI tools, designing an integrated system, and combining implementation, monitoring, and scaling into a cohesive iterative process. Key technologies include centralized BIM repositories, machine learning-based predictive analytics, Internet of Things (IoT) sensors, and robotic process automation (RPA). The findings show that these tools significantly improve data organization, proactive planning, regulatory compliance, stakeholder collaboration, and overall project efficiency. While qualitative in nature, this study offers globally relevant insights and actionable strategies for advancing digital transformation in renovation practices, with a focus on scalability, continuous improvement, and alignment with regulatory frameworks. Full article

Federated learning (FL) enables privacy-preserving adaptation of large language models (LLMs) across distributed clients. However, deploying FL in edge environments remains challenging because of the high communication overhead of full-model updates. Recent advances in parameter-efficient fine-tuning (PEFT), particularly low-rank adaptation (LoRA), have substantially reduced update sizes by injecting lightweight trainable matrices into pretrained transformers, thereby making FL with LLMs more feasible. In this paper, we propose LoRaC-GA, a communication-aware optimization framework that dynamically determines the optimal number of clients to participate in each round under a fixed bandwidth constraint. We formulated a max-min objective to jointly maximize the model accuracy and communication efficiency and solved the resulting non-convex problem using a genetic algorithm (GA). To further reduce the overhead, we integrated a structured peer-to-peer collaboration protocol with ${log}_{2}K$ complexity, enabling scalable communication without full connectivity. The simulation results demonstrate that LoRaC-GA adaptively selects the optimal client count, achieving competitive accuracy while significantly reducing the communication cost. The proposed framework is well-suited for bandwidth-constrained edge deployments involving large-scale LLMs. Full article

The integration of nanotheranostics into cancer treatment represents a transformative shift in oncology, combining precision diagnostics with targeted therapeutic interventions. This manuscript explores the advancements in nanotechnology-driven cancer therapies, highlighting the role of engineered nanoparticles, such as liposomes, dendrimers, polymeric micelles, and virus-like particles, in enhancing drug delivery, real-time imaging, and tumor-specific targeting. Additionally, emerging therapies, including immunotherapy, gene editing, and chromophore-assisted light inactivation (CALI), are discussed in the context of personalized medicine. The convergence of these strategies is poised to redefine cancer treatment paradigms, improving therapeutic efficacy while minimizing systemic toxicity. This review outlines the key challenges, current limitations, and future directions in nanotheranostic applications, emphasizing the need for interdisciplinary collaboration to optimize their clinical translation. Full article

This study focuses on human awareness, a critical component in human–robot interaction, particularly within agricultural environments where interactions are enriched by complex contextual information. The main objective is identifying human activities occurring during collaborative harvesting tasks involving humans and robots. To achieve this, we propose a novel and lightweight deep learning model, named 1D-ResNeXt, designed explicitly for recognizing activities in agriculture-related human–robot collaboration. The model is built as an end-to-end architecture incorporating feature fusion and a multi-kernel convolutional block strategy. It utilizes residual connections and a split–transform–merge mechanism to mitigate performance degradation and reduce model complexity by limiting the number of trainable parameters. Sensor data were collected from twenty individuals with five wearable devices placed on different body parts. Each sensor was embedded with tri-axial accelerometers, gyroscopes, and magnetometers. Under real field conditions, the participants performed several sub-tasks commonly associated with agricultural labor, such as lifting and carrying loads. Before classification, the raw sensor signals were pre-processed to eliminate noise. The cleaned time-series data were then input into the proposed deep learning network for sequential pattern recognition. Experimental results showed that the chest-mounted sensor achieved the highest F1-score of 99.86%, outperforming other sensor placements and combinations. An analysis of temporal window sizes (0.5, 1.0, 1.5, and 2.0 s) demonstrated that the 0.5 s window provided the best recognition performance, indicating that key activity features in agriculture can be captured over short intervals. Moreover, a comprehensive evaluation of sensor modalities revealed that multimodal fusion of accelerometer, gyroscope, and magnetometer data yielded the best accuracy at 99.92%. The combination of accelerometer and gyroscope data offered an optimal compromise, achieving 99.49% accuracy while maintaining lower system complexity. These findings highlight the importance of strategic sensor placement and data fusion in enhancing activity recognition performance while reducing the need for extensive data and computational resources. This work contributes to developing intelligent, efficient, and adaptive collaborative systems, offering promising applications in agriculture and beyond, with improved safety, cost-efficiency, and real-time operational capability. Full article

This study identifies twelve critical factors influencing the successful implementation of Blockchain Technology (BCT) in supply chain processes, addressing the significant gap in understanding the practical and theoretical complexities of blockchain implementation. Through semi-structured interviews and grounded theory analysis, the concept of Decentralized Coordination and Sustainability was derived in addition to themes such as Strategic Alignment and Leadership Commitment, Organizational Adaptability and Resilience, Data Security and Integrity, User Preparedness and Engagement. These themes provide a novel theoretical lens to explore blockchain’s role in enhancing supply chain transparency, traceability, and collaboration. The study bridges strategic frameworks with decentralized technologies, providing actionable insights for successful implementation in the supply chain discipline. This research advances the application of grounded theory in blockchain research, encouraging qualitative methods to explore emerging technologies within complex organizational systems. This study establishes a foundation for future research to enhance our understanding of blockchain’s transformative impact in supply chain contexts. Full article

The digital transformation of Tibetan cultural tourism is hindered by high manual costs, weak semantic adaptability, and cultural security risks. To address these, this paper proposes RLT2C, a “Rule+LLM-Verify” approach to automated and culturally secure KG construction. It employs a lightweight-large model collaboration mechanism, where a fine-tuned lightweight model generates initial Cypher statements, rigorously verified by LLMs for local semantic accuracy and cultural compliance. This two-stage process, combined with a dynamic-static cultural constraint system, ensures high efficiency and preserves cultural integrity, supporting knowledge-driven naked-eye 3D immersive experiences. Experimental results on 1200 Tibetan tourism-related texts show that RLT2C outperforms baselines in construction efficiency (14.5 triples/100 words), relationship accuracy (91.5%), local semantic adaptability (87.9%), and graph redundancy rate (5.4%). RLT2C exhibits strong practicality and scalability. The constructed KG serves not only as an information repository but also as a foundational engine for immersive visualization. By acting as a “central index” for 3D assets and a “safety gatekeeper” for content generation, it enables the dynamic and secure rendering of culturally authentic naked-eye 3D experiences from natural language queries. Full article

Environmental DNA (eDNA) metabarcoding has transformed marine biodiversity monitoring by allowing non-invasive, cost-effective detection of species with high resolution across diverse marine habitats. A systematic literature search was conducted using Google Scholar, Scopus, and the Qatar University Library databases. Relevant peer-reviewed publications were screened and selected based on predefined inclusion criteria to ensure comprehensive coverage of studies. This review synthesizes advances in global and regional eDNA applications, emphasizing the Middle East and North Africa (MENA) region, which faces unique environmental extremes, high endemism, and significant data gaps. eDNA metabarcoding often outperforms traditional methods under comparable sampling effort to traditional surveys in detecting rare, cryptic, and invasive taxa, but technical challenges like incomplete reference databases, primer biases, PCR inhibitors, and inconsistent methodologies limit their effectiveness, particularly in understudied areas such as MENA. Recent developments, including multi-marker approaches, autonomous samplers, and next-generation sequencing, are enhancing detection precision and enabling broader, real-time monitoring. In the MENA region, early studies have revealed eDNA’s potential for habitat distinction, biogeographic research, pollution assessment, and the early discovery of non-indigenous species, although progress is hindered by gaps in reference libraries, infrastructure, and regulation. This review underscores the urgent need for regional collaboration, standardized protocols, and capacity-building. By integrating eDNA with traditional methods and leveraging emerging technologies, the MENA region can establish itself as a leader in marine biomonitoring under extreme environmental conditions, providing actionable insights for conservation and sustainable management of its unique marine ecosystems. Full article

In the context of the global growth of the collaborative economy, Airbnb has established itself as one of the most influential players in the transformation of the tourist accommodation market, especially in the reconfiguration of urban tourist accommodation. This article examines empirically and critically how this platform operates in Buenos Aires, the most visited city in Argentina and one of the main tourist hubs in South America. Based on a database of 17,249 active listings, the price formation of accommodations is analyzed using a comparative methodological approach between a general linear model (GLM) and a geographically weighted regression (GWR) model. While the GLM allows for capturing general patterns, the GWR reveals significant territorial differences, offering a detailed reading of the spatial behavior of prices in the city. The results show that variables such as the capacity of the accommodation, its type (full house), the host’s condition, the users’ ratings and the proximity to strategic points such as the subway or Plaza de Mayo have a significant influence on prices. In addition, it is shown that the influence of these variables varies by neighborhood, confirming that the pricing logic in Airbnb is deeply territorialized. This study not only provides novel empirical evidence for a Latin American city that has been little explored in the international literature, but also offers useful tools for hosts, urban planners and public decision makers. Its main contribution lies in showing that prices respond not only to accommodation attributes, but also to broader spatial inequalities, opening the debate on the effects of Airbnb on housing access and urban management in cities with strained real estate markets. By shedding light on these territorial asymmetries, the study offers valuable insights for public policy and urban governance and contributes directly to the achievement of Sustainable Cities and Communities (SDG 11), while also supporting Industry, Innovation and Infrastructure (SDG 9) and Reduced Inequalities (SDG 10), by providing practical knowledge that fosters more equitable and sustainable urban development. Full article