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18 pages, 1885 KB  
Article
Perspectives on Agency in New Kingdom Theban Tombs
by Marina Sartori
Arts 2026, 15(7), 147; https://doi.org/10.3390/arts15070147 (registering DOI) - 23 Jun 2026
Viewed by 31
Abstract
Far from being merely repetitive, the painted decoration in Theban tombs of the New Kingdom reveals a rich variety of individual artistic choices, and therefore offers a privileged point of view for the study of agency in ancient Egypt. By examining selected pictorial [...] Read more.
Far from being merely repetitive, the painted decoration in Theban tombs of the New Kingdom reveals a rich variety of individual artistic choices, and therefore offers a privileged point of view for the study of agency in ancient Egypt. By examining selected pictorial units from a number of tombs, personally investigated by the author, this paper will explore the painters’ approaches to tomb decoration through the lens of the agency theory developed by Alfred Gell. Personal intervention can be recognised in many little details which ensure that no two Theban chapels are identical, even where the same scenes are represented. These variations undoubtedly sprang from the individual choices of the artists. Preparatory ostraca show the basic layout of text and scenes, with the division into registers and columns, but these remain only preparatory sketches. All the final details in the lines, colours, and components that make up a figure or a sign offer room for modifications. By analysing how artists interacted with the single pictorial units they were tasked with painting, their patterns of action and horizons of freedom become clearer, offering us a deeper insight into the role of Theban painters in the history of the site. Full article
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26 pages, 7111 KB  
Article
Elucidating and Collating the True Scriptures: A Study of the Newly Discovered Qing-Dynasty Editions of the Nanbei dou jing chanwei
by Qinsheng Shi
Religions 2026, 17(6), 732; https://doi.org/10.3390/rel17060732 (registering DOI) - 18 Jun 2026
Viewed by 201
Abstract
The veneration of the Southern and Northern Dippers stands at the heart of the Daoist tradition of astral worship, and the compilation of the Nanbei dou jing (Scriptures of the Southern and Northern Dippers) during the Northern Song dynasty marks a defining moment [...] Read more.
The veneration of the Southern and Northern Dippers stands at the heart of the Daoist tradition of astral worship, and the compilation of the Nanbei dou jing (Scriptures of the Southern and Northern Dippers) during the Northern Song dynasty marks a defining moment in the codification of this belief system. Over the course of their transmission, however, the texts accumulated errors while their exegetical tradition fell into increasing neglect. During the Jiaqing and Daoguang reigns of the Qing dynasty, local literati in Yunnan employed the practice of spirit-writing to compose the Beidou jing chanwei and the Nandou jing chanwei in succession, with the twin aims of reconstructing the canonical texts and reviving their interpretive tradition. This article examines these two commentaries along three axes—textual character, philological value, and religious thought—and argues that they are at once liturgical handbooks of the Dongjing Association and the most significant Qing-dynasty annotations of the Nanbei dou jing known to date. Philologically, they preserve variant readings of considerable value for the reconstruction of the textual history of both scriptures. Doctrinally, the commentators fused Daoist astral worship with Buddhist karmic cosmology, Confucian ritual cultivation, and the discourse of inner alchemy, yielding a form of three-teachings syncretism distinctively shaped by its regional context. Through these rare sources, this article seeks to open new perspectives on Daoist textual production, inter-religious exchange, and ritual practice in Qing-dynasty Yunnan. Full article
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12 pages, 1045 KB  
Article
“Blue, Upon Your Grave”: The Testament of Derek Jarman in Blue (1996)
by Cían Ó Donnchadha
Arts 2026, 15(6), 142; https://doi.org/10.3390/arts15060142 - 17 Jun 2026
Viewed by 280
Abstract
This article develops an understanding of Derek Jarman’s Blue (1993) as a testament film. It considers the filmmaker’s personal philosophy and concept of history, proposing the resonance of Walter Benjamin’s angel of history, the epitome of Benjamin’s contention with the ‘continuum of [...] Read more.
This article develops an understanding of Derek Jarman’s Blue (1993) as a testament film. It considers the filmmaker’s personal philosophy and concept of history, proposing the resonance of Walter Benjamin’s angel of history, the epitome of Benjamin’s contention with the ‘continuum of history’ in his final text, Theses on the Philosophy of History. This article considers the testament of Blue as a concept of history, contextualised by Jarman’s reckoning with the HIV/AIDS pandemic, and thereby with his own mortality, as Jarman’s attestation of a model of history (both personal and national, or coinhered as ‘memory’), which answers the demand of the ‘tradition of the oppressed.’ Theories of profane illumination, second nature, and the crisis of representation are explicated for the purposes of identifying Jarman’s model of history, and of his refusal of a historicist conception. In addition, it proposes the context of the AIDS crisis, as the ‘state of emergency’, the condition which compels this concept of history. Full article
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16 pages, 1989 KB  
Article
Friar Hernando de Talavera and the Brief and Very Useful Doctrine: Literacy and Evangelisation in Granada, Castile and the Americas
by Jesús R. Folgado-García
Religions 2026, 17(6), 705; https://doi.org/10.3390/rel17060705 - 12 Jun 2026
Viewed by 242
Abstract
Friar Hernando de Talavera can be considered the main strategist of evangelisation at the end of the 15th century in the recently conquered Kingdom of Granada. To this end, he used the publication Breve y muy provechosa doctrina de lo que debe saber [...] Read more.
Friar Hernando de Talavera can be considered the main strategist of evangelisation at the end of the 15th century in the recently conquered Kingdom of Granada. To this end, he used the publication Breve y muy provechosa doctrina de lo que debe saber todo cristiano together with eight other very useful treatises [Brief and Very Useful Doctrine of What Every Christian Should Know, with Eight Other Very Useful Treatises], which he accompanied with his Instrucción a los vecinos del Albaicín [Instruction to the Residents of the Albaicín]. Successive editions of the catechism and some books included under the generic title Breve y muy provechosa doctrina [A Brief and Very Useful Doctrine] throughout the 16th century demonstrated its doctrinal soundness and pastoral effectiveness. Furthermore, they were later used not only for catechesis but also for literacy in the Kingdom of Granada and in the early days of the American conquest. The study will systematically present the different editions and their intentions from the Granada incunabulum to the present day. The texts composed by the first archbishop of Granada were the words used to unite several kingdoms and conquered territories in the faith and in the Castilian language. The aim of this study is to provide a systematic overview of the various editions published throughout history and to analyse the influence that some of them exerted on the subsequent development of evangelisation in Granada, Castile, and possibly the Americas. Full article
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17 pages, 358 KB  
Article
Jesuit Accommodation and Early Chosŏn Catholicism: Text-Mediated Reception Without Resident Missionaries
by Jae Won Chang
Religions 2026, 17(6), 688; https://doi.org/10.3390/rel17060688 - 8 Jun 2026
Viewed by 204
Abstract
Late eighteenth-century Chosŏn Korea presents a distinctive case in the history of Christian missions: a Catholic community emerged without the sustained presence of foreign missionaries. This article examines that distinctiveness through the lens of text-mediated local reception. Since the seventeenth century, the writings [...] Read more.
Late eighteenth-century Chosŏn Korea presents a distinctive case in the history of Christian missions: a Catholic community emerged without the sustained presence of foreign missionaries. This article examines that distinctiveness through the lens of text-mediated local reception. Since the seventeenth century, the writings of Matteo Ricci had rendered Christian doctrine intelligible within a Confucian framework through Jesuit accommodation. In late Chosŏn, these texts moved beyond scholarly curiosity and became a medium of criticism, moral reflection, and, for some readers, communal religious practice, particularly among politically marginalized Namin (Southern) circles and Silhak (Practical Learning)-oriented thinkers. The reception of Catholicism unfolded in stages. Sinographic texts composed by Jesuit missionaries were first understood within an existing Confucian horizon and then selectively appropriated by local readers. In some cases, this process led to baptism, early lay organization, and communal religious life. Through comparison with China, Japan, and Vietnam, this study argues that Chosŏn represents a distinctive case in which translated Christian texts, local appropriation, and community formation converged without a sustained missionary presence. It further shows that this process was shaped not by one-way transmission alone, but by the active agency of local readers and a bidirectional process of cultural translation. Full article
9 pages, 195 KB  
Article
Reproductive Trauma and Archival Reconstruction in Postwar Canada: Heather Marshall’s Looking for Jane
by Oana Celia Gheorghiu
Humanities 2026, 15(6), 76; https://doi.org/10.3390/h15060076 - 4 Jun 2026
Viewed by 395
Abstract
This article examines Heather Marshall’s Looking for Jane as a literary engagement with the history of reproductive control in postwar Canada. It contends that the novel redefines trauma as a structurally generated condition, influenced by institutional and social constraints. Through its fragmented, multi-generational [...] Read more.
This article examines Heather Marshall’s Looking for Jane as a literary engagement with the history of reproductive control in postwar Canada. It contends that the novel redefines trauma as a structurally generated condition, influenced by institutional and social constraints. Through its fragmented, multi-generational narrative, comprising letters, testimonies, and disjointed timelines, the text reconstructs a history that survives only in partial, mediated, and often unstable traces, foregrounding the difficulties of rendering reproductive trauma historically visible. By contextualising individual experiences within a broader framework of institutional oversight and referencing documented practices such as forced adoption and restricted access to abortion, the novel links literary form to historical realities. Its concluding paratext extends this dialogue into the present, engaging the reader directly and emphasising the ongoing significance of reproductive trauma in contemporary discourses on responsibility and recognition. Full article
(This article belongs to the Section Literature in the Humanities)
9 pages, 183 KB  
Article
Women’s Celibacy and the Propagation Imperative in Irish Science Fiction
by Jack Fennell
Humanities 2026, 15(6), 73; https://doi.org/10.3390/h15060073 - 29 May 2026
Viewed by 281
Abstract
This article considers the literary exploration of women’s celibacy through the prism of science fiction, beginning with an overview of the genre’s often-retrograde engagements with the subjects of marriage, reproduction and heteronormative ideology. Alongside this genre context, a 19th-century Irish historical context is [...] Read more.
This article considers the literary exploration of women’s celibacy through the prism of science fiction, beginning with an overview of the genre’s often-retrograde engagements with the subjects of marriage, reproduction and heteronormative ideology. Alongside this genre context, a 19th-century Irish historical context is outlined, juxtaposing genre history with the ‘matrimonial’ rhetoric that arose following the 1801 Act of Union, which framed the merging of Ireland into the United Kingdom as a ‘marriage’ between Ireland and Great Britain, with Ireland represented as the bride. In the overlap between these two contexts, this article identifies several future-set Irish novels that address this rhetoric directly, while also tracing its (perhaps unconscious) impact in other texts, before moving on to consider one novel in particular: Mercia, the Astronomer Royal (1895) by Amelia Garland Mears. The article concludes by arguing that science fiction’s past missteps with regard to marriage and sex can be explained by the fact that traditional, patriarchal marriage is in fact fundamentally unsuited to a genre primarily concerned with the future, resulting in reactionary overcompensation. Full article
(This article belongs to the Special Issue Celibacy in Irish Women’s Writing)
14 pages, 265 KB  
Article
Islam, Modernity, and the ‘Problem-Case’ of Religion
by Nasar Meer
Genealogy 2026, 10(2), 62; https://doi.org/10.3390/genealogy10020062 - 26 May 2026
Viewed by 410
Abstract
This article examines how social science has recurrently positioned Islam as a problem-case for European narratives of modernity, simultaneously comparable as ‘a religion’ yet cast as the religion that ‘doesn’t fit’ secularisation, differentiation, and liberal public-reason expectations. Moving beyond the view that social [...] Read more.
This article examines how social science has recurrently positioned Islam as a problem-case for European narratives of modernity, simultaneously comparable as ‘a religion’ yet cast as the religion that ‘doesn’t fit’ secularisation, differentiation, and liberal public-reason expectations. Moving beyond the view that social science merely misdescribed Islam, this article argues that Islam has often been made to carry an explanatory burden internal to Europe’s self-narration, a limit-case through which stalled secularisation, anxious liberalism, and contested universals are rendered intelligible and governable. The article returns to canonical texts that helped establish such comparative imagination, including Hegel’s philosophy of history, Weber’s typologies of religious ‘bearers,’ and Gellner’s account of Islam as a comprehensive ‘blueprint’ of social order, to show how durable contrast effects were installed and later reactivated in contemporary debates on secularism, gender, security, and belonging. Drawing on Asad’s critique of the category ‘religion’, the article theorises ‘disruption’ as a recurring genre through which Islam is made exceptional, disruptive to secularisation theory, to accounts of modern differentiation, and to liberal self-understanding. It concludes by appealing to a reflexive sociology of religion that historicises its own categories, compares entanglements rather than civilisations, and treats Muslim intellectual traditions as theory-producing interlocutors rather than merely empirical ‘data’. Full article
(This article belongs to the Special Issue Secularism and Race-Religion Entanglements)
29 pages, 11467 KB  
Article
Temporal Screening of High-Risk Food Service Inspections in New York State, 2023–2025: A Case Study Using Multimodal Evidential Learning
by Zi-Heng Cai and Wang-Chin Tsai
Foods 2026, 15(11), 1864; https://doi.org/10.3390/foods15111864 - 25 May 2026
Viewed by 349
Abstract
Food safety inspection systems generate rich historical records, yet converting these records into actionable pre-inspection risk signals remains challenging under limited regulatory resources. The objective of this study was to develop and evaluate a temporally valid, leakage-free, multimodal screening framework for identifying high-risk [...] Read more.
Food safety inspection systems generate rich historical records, yet converting these records into actionable pre-inspection risk signals remains challenging under limited regulatory resources. The objective of this study was to develop and evaluate a temporally valid, leakage-free, multimodal screening framework for identifying high-risk food service inspections before the upcoming inspection outcome is known. Existing studies have improved inspection prediction with machine learning, but many focus on contemporaneous classification rather than temporally valid high-risk screening, and few jointly model historical numeric behavior, prior narrative context, and predictive uncertainty. To address this gap, this study proposes a temporal high-risk food inspection screening framework based on multimodal evidential learning. Using New York State food service inspection data, we constructed a event-level dataset of 55,454 inspections from 20,082 establishments and predicted whether an upcoming inspection would be high-risk using only pre-inspection information. The proposed evidential deep learning multilayer perceptron integrates current metadata, longitudinal numeric history, and historical inspection comments while producing calibrated uncertainty estimates for selective prediction. On the held-out test set, the proposed model achieved the best overall performance, with an AUROC of 0.846, AUPRC of 0.424, F1 score of 0.431, Brier score of 0.063, and ECE of 0.012, outperforming strong tabular baselines including CatBoost and TabM. Under selective prediction, its retained-set F1 increased from 0.431 at full coverage to 0.542 at 80% coverage. Explainability analysis further showed that predictive gains were driven primarily by historical compliance dynamics, with historical text providing complementary contextual value. These findings support the use of temporally valid, uncertainty-aware multimodal models for risk-based food inspection prioritization. Full article
(This article belongs to the Section Food Quality and Safety)
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26 pages, 5296 KB  
Article
Effects of the Light Environment on Visual Comfort and Perceptual Preference in Static Exhibition Spaces of History Museums
by Jingyun Hu, Xiaoxing Zhang, Lili Jiang and Xuesong Guan
Buildings 2026, 16(10), 2016; https://doi.org/10.3390/buildings16102016 - 20 May 2026
Viewed by 255
Abstract
History museum exhibition spaces convey historical and cultural information through static artifacts, graphic–text narratives, and spatial atmosphere. The light environment affects not only exhibit visibility but also visitors’ visual comfort and perceptual preference. However, existing studies mainly focus on single lighting parameters, and [...] Read more.
History museum exhibition spaces convey historical and cultural information through static artifacts, graphic–text narratives, and spatial atmosphere. The light environment affects not only exhibit visibility but also visitors’ visual comfort and perceptual preference. However, existing studies mainly focus on single lighting parameters, and perceptual differences across multiple lighting conditions remain insufficiently understood. This study investigated static exhibition spaces in history museums through a comparison of 12 virtual lighting conditions generated from different combinations of ambient illuminance, exhibit illuminance, and correlated color temperature. Visitors’ visual behavior and subjective perception were evaluated through eye-tracking experiments, heatmap analysis, and Likert-scale ratings. Different lighting combinations significantly affected visual attention allocation and subjective evaluation. Total duration of fixation, number of fixations, and average pupil diameter showed significant differences across conditions, whereas average fixation time did not. Overall, moderate ambient illuminance and higher exhibit illuminance were associated with more stable visual responses and more positive perceptual evaluations, while correlated color temperature showed a regulatory effect within the tested range of 3000–4000 K. These findings provide preliminary evidence for understanding perceptual responses to lighting combinations in static exhibition spaces and may inform future field-based validation of museum lighting design. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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25 pages, 2298 KB  
Article
Reading Significance: Using AI to Study Historic Recognition
by Melissa Rovner and Emily Talen
Urban Sci. 2026, 10(5), 279; https://doi.org/10.3390/urbansci10050279 - 15 May 2026
Viewed by 425
Abstract
The National Register of Historic Places (NR) is a structured artifact of meaning-making that encodes disciplinary values linking architectural and cultural significance to wealth and stylistic distinction. In doing so, it systematically underrepresents vernacular, working-class, and the built environments of racially and ethnically [...] Read more.
The National Register of Historic Places (NR) is a structured artifact of meaning-making that encodes disciplinary values linking architectural and cultural significance to wealth and stylistic distinction. In doing so, it systematically underrepresents vernacular, working-class, and the built environments of racially and ethnically marginalized communities. This paper uses artificial intelligence (AI) to examine how that meaning is constructed. We analyze the preservation record across three scales: a national dataset of 100,117 NR listings (1966–2025), a state-level profile of Illinois’s 1997 NR listings, and a close analysis of Lake Forest, Illinois, a community whose exceptional concentration of NR-listed estate architecture makes it an ideal site for examining how preservation significance has been defined and what it excludes. Two parallel AI methods are applied to eighteen Lake Forest nomination documents and their associated photographs. Natural Language Processing (NLP) analyzes nomination text to trace how preservation professionals connect buildings to cultural value; blind AI image analysis examines the same properties to assess how a model trained on cultural imagery constructs visual meaning independently. NLP analysis reveals a corpus dominated by architectural description, with social history, landscape, and labor systematically underrepresented. The visual analysis confirms and amplifies the nomination record’s class-based assumptions while reproducing the same omissions regarding labor, diversity, and community context. These findings inform debates about AI’s potential to audit existing listings and support nominations for underrepresented property types, while showing that without deliberate corrective design and policy reform, such tools are as likely to replicate the preservation system’s inequities as to repair them. Full article
(This article belongs to the Special Issue AI-Driven Land Use Planning for Sustainable Cities)
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18 pages, 448 KB  
Review
AI-Assisted Training for Teleconsultation Competencies in Undergraduate Medical Education: A Narrative Review
by Wojciech Michał Glinkowski, Barbara Jacennik, Aldona Katarzyna Jankowska, Tomasz Cedro, Szymon Wilk and Rafał Doniec
Appl. Sci. 2026, 16(10), 4858; https://doi.org/10.3390/app16104858 - 13 May 2026
Cited by 1 | Viewed by 464
Abstract
Telemedicine has become a routine component of healthcare delivery, creating a need for dedicated undergraduate training in teleconsultation-specific competencies. Although artificial intelligence (AI)-assisted educational systems have been proposed as scalable tools to support teleconsultation training, the evidence remains fragmented, and their educational role [...] Read more.
Telemedicine has become a routine component of healthcare delivery, creating a need for dedicated undergraduate training in teleconsultation-specific competencies. Although artificial intelligence (AI)-assisted educational systems have been proposed as scalable tools to support teleconsultation training, the evidence remains fragmented, and their educational role is not yet clearly defined. Objective: To map and critically synthesize empirical evidence on AI-assisted teleconsultation training systems used in undergraduate medical education, with attention to skill domains, system capabilities, and implementation considerations. Methods: A structured narrative review with transparent search and study selection procedures was conducted. Literature published between January 2019 and December 2025 was identified through searches of major bibliographic databases and supplementary semantic and citation-based sources. Studies involving undergraduate medical students and evaluating AI-assisted interventions targeting teleconsultation-related skills were included. Results: Eight empirical full-text studies met the final eligibility criteria and were included in the structured narrative synthesis. Across the included studies, AI-assisted systems tended to show favorable patterns in structured domains such as verbal communication, history-taking, and selected aspects of early clinical reasoning during virtual consultations. Evidence regarding nonverbal communication and empathic or relational skills was more limited and methodologically heterogeneous, and human-based simulation remained important in these domains. Students generally reported favorable perceptions of usability, accessibility, and psychological safety, although satisfaction and perceived realism were not uniformly superior to human-based approaches. AI-assisted systems also appeared scalable and potentially cost-efficient, particularly as preparatory or supplementary training modalities. Conclusions: Current evidence suggests that AI-assisted teleconsultation training systems may be useful as preparatory and supportive tools in undergraduate medical education, particularly for structured and repeatable components of remote consultation practice. However, the evidence base remains limited and heterogeneous, and these systems do not replace human-led training for relational, nonverbal, and context-sensitive competencies. Their educational value appears greatest within blended training models that align platform capabilities with specific teleconsultation skills. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
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16 pages, 377 KB  
Article
An Independent Śiva Purāṇa and Śiva’s Reverence to the Man-Lion
by Benjamin J. Fleming
Religions 2026, 17(5), 560; https://doi.org/10.3390/rel17050560 - 7 May 2026
Viewed by 620
Abstract
This article traces the history of a small independent Śiva Purāṇa that has circulated across South Asia for centuries. Rather than focusing on its theological and narrative content alone, this article also focuses on the text’s material manifestation in three distinct time periods: [...] Read more.
This article traces the history of a small independent Śiva Purāṇa that has circulated across South Asia for centuries. Rather than focusing on its theological and narrative content alone, this article also focuses on the text’s material manifestation in three distinct time periods: Medieval, Mughal, and Colonial. The first section considers its material and textual history with attention to manuscripts. The second section elucidates the value of this approach by considering one episode from the text: the Śarabha-Narasiṃha story. In the process of illuminating the Śiva Purāṇa tradition, this article uses this Purāṇic example to experiment with approaches to scriptural materiality through Pierre Bourdieu’s lens of a “double existence”. Full article
(This article belongs to the Special Issue A Sociological Approach to the Study of the Sanskrit Purānas)
18 pages, 770 KB  
Article
From Esoteric Alchemical Canon to Publicly Circulating Book: A Study on Longmeizi 龍眉子 and The Textual Circulation History of the Jinye Huandan Yinzheng Tu 金液還丹印證圖
by Xuetao Liu
Religions 2026, 17(5), 538; https://doi.org/10.3390/rel17050538 - 30 Apr 2026
Viewed by 517
Abstract
Longmeizi 龍眉子 was an inheritor of the Southern Lineage of Daoism 道教南宗 under Weng Baoguang 翁葆光. By tracing the historical documentation of Longmeizi’s Daoist lineage, it becomes evident that the narrative details were continuously enriched through textual accumulation. By tracing and analyzing the [...] Read more.
Longmeizi 龍眉子 was an inheritor of the Southern Lineage of Daoism 道教南宗 under Weng Baoguang 翁葆光. By tracing the historical documentation of Longmeizi’s Daoist lineage, it becomes evident that the narrative details were continuously enriched through textual accumulation. By tracing and analyzing the formative history of documents related to Longmeizi’s Daoist lineage, it is evident that in the process of forming this Daoist lineage, lineage identity 宗派認同 was continuously solidified and even “labeled 標籤化” within these layered texts. The transmission genealogy between patriarchs across generations gradually became clear, definite, and verifiable. After Longmeizi compiled the Jinye Huandan Yinzheng Tu 金液還丹印證圖 (Illustrations of the Return of the Liquified Gold to the Cinnabar Field) from the Jiading period (1208–1224) of the Southern Song Dynasty to the beginning of the Yuan Dynasty, this book was initially transmitted within the Daoist lineage: Longmeizi → Bai Yuchan 白玉蟾 → Wang Jinchan 王金蟾. By the end of the Yuan Dynasty, a literatus named Yuanyangzi Lin Jing 元阳子林静 from Wuxing 吴兴 had also read this book. During the Ming and Qing dynasties, the mode of transmission for the Jinye Huandan Yinzheng Tu shifted from being primarily transmitted orally within Daoist circles to being primarily disseminated through the printing and circulation of books. This led to the emergence of many different versions and commentaries of the Jinye Huandan Yinzheng Tu. Through the compilation and printing of book series, the Jinye Huandan Yinzheng Tu gained broad circulation during the Ming and Qing dynasties. Its annotators, publishers, and readers spanned various identities and social classes, while its geographic reach extended to the Central Plains (Zhongyuan 中原), Southwest China, and Jiangnan regions. By examining the textual circulation history of the Jinye Huandan Yinzheng Tu, it can be observed that the development of the book printing industry during the Ming and Qing periods, particularly the flourishing of series publications, facilitated a shift in the primary mode of transmission for Daoist texts and even in the nature of the texts themselves. On the other hand, the case study of the Jinye huandan yinzheng tu is an example that illustrates the diversity and richness in the methods of Daoist cultural transmission and their development during the Ming and Qing dynasties. Full article
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24 pages, 2304 KB  
Review
The Changing Concept in the History of Schizophrenia
by Eugenio Cavalli, Giuseppe Rosario Pietro Nicoletti and Ferdinando Nicoletti
Brain Sci. 2026, 16(5), 447; https://doi.org/10.3390/brainsci16050447 - 23 Apr 2026
Viewed by 1210
Abstract
Background/Objectives: Schizophrenia is one of the most extensively studied yet conceptually unstable disorders in the history of medicine and brain sciences. Since its formalization at the turn of the twentieth century, the disorder has been repeatedly redefined, reflecting changes in clinical observation, [...] Read more.
Background/Objectives: Schizophrenia is one of the most extensively studied yet conceptually unstable disorders in the history of medicine and brain sciences. Since its formalization at the turn of the twentieth century, the disorder has been repeatedly redefined, reflecting changes in clinical observation, diagnostic philosophy, and neuroscientific models of brain function. The objective of this review is to critically examine the historical evolution of schizophrenia as a medical construct and to analyze how shifts in diagnostic systems have shaped the search for biological and molecular biomarkers. Methods: A narrative-historical review of the literature was conducted, integrating classical psychiatric texts, diagnostic manuals, and contemporary neuroscientific studies. Key milestones in the conceptualization of schizophrenia were analyzed alongside the development of biological hypotheses, including neurochemical, electrophysiological, neuroimaging, genetic, immunological, omics-based, and digital approaches. Emphasis was placed on identifying conceptual continuities, ruptures, and methodological limitations across historical periods. Results: The analysis reveals that the evolution of schizophrenia has been characterized by increasing diagnostic standardization accompanied by growing biological heterogeneity. While successive biological models have provided valuable insights into specific aspects of the disorder, none have yielded single, robust diagnostic biomarkers. Instead, findings consistently reflect partial overlaps between clinical phenotypes and biological signals, strongly influenced by historically derived diagnostic categories. Conclusions: The persistent absence of definitive diagnostic biomarkers for schizophrenia reflects not only technical limitations but also the historical construction of the disorder as a heterogeneous clinical category. Understanding this historical context is essential for interpreting current findings in brain sciences. Future research is likely to benefit from stratification-based, dimensional, and integrative frameworks that move beyond categorical diagnosis while preserving clinical relevance. Full article
(This article belongs to the Section Molecular and Cellular Neuroscience)
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